( ) pinoresinol

(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.

Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1 Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1).

(±)-Pinoresinol is a natural product for research related to life sciences. The catalog number is TN5415 and the CAS number is 4263-88-1.

(+)-pinoresinol-β-D-glucoside; (+)-pinor is the major active furanoid lignan in Lianxian. It shows antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory activities.

Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.

1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.

Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic agent.

(-)-Pinoresinol 4-O-glucoside, a natural product, is derived from Lonicera japonica THUNB.

(+)-Pinoresinol monomethyl ether 4-O-β-D-glucoside is a natural product.