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TargetMol | Tags Natural Product Categories

Tacca

TargetMol offers a curated selection of compounds derived from the Tacca genus and maintains a collection of over 25,000 high-purity natural products and natural product monomer reference standards (sourced from plants, microorganisms, marine organisms, and animals). Utilizing a refined classification system that covers multi-dimensional information such as genus, family, biological activity, and structural types, our products feature clear source information and standardized data, making them suitable for reference standard research, high-throughput screening, virtual screening, and drug discovery studies.

  • Taccalonolide A
    TN2254108885-68-3
    Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells.
    • $48
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  • Taccalonolide B
    TN2256108885-69-4
    Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
    • $48
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  • Taccafurostanoside A
    TN8256290809-76-6
    Taccafurostanoside A is a pentacyclic steroidal compound used in life science research.
    • $460
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  • Taccalonolide AJ
    TN22551349904-82-0
    Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that the lack of antitumor efficacy seen with systemic administration of AJ is likely due to its sh
    • $290
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