Hypoxidaceae

1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidative injury induced by H2O2, suggesting that this compound may constitute a promising intervention against cardiovascular disorders.

Orcinol glucoside (Sakakin) (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effects.

orcinol (5-Methylresorcin) is anxiolytic agent without sedative effect.

Orcinol gentiobioside is a natural product extracted from C. breviscapa rhizome tubers with anti-OP activity.

2,6-Dimethoxybenzoic acid is an o-methoxybenzoic acid and its derivatives that inhibit fungi and bacteria.

Nyasicol is a natural product found in the methanol extract of fresh leaves of Molineria latifolia.

Curculigoside B is a naturally occurring phenolic compound traditionally used in Asian to protect against osteoporosis and maintaining skeletal integrity. Curculigoside B exerts antioxidant, anti-aging, immunomodulatory, and anti-inflammatory functions, while effectively preventing pathological bone loss, establishing this compound as a validated osteoprotective therapeutic candidate of increasing interest in research.

Nyasicoside may have promising and beneficial thrombolytic activity.

Nyasicol 1,2-acetonide is a natural product for research related to life sciences. The catalog number is TN4680 and the CAS number is 1432057-64-1.

Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.

Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside has antioxidative activity.

Curculigoside C is a natural product of Curculigo, Amaryllidaceae. The catalog number is TN3732 and the CAS number is 851713-74-1. Curculigoside C can be used as a reference standard.

Cimilactone A shows significant anticomplement activity (IC(50)= 28.6 microm).