Celastrus

Tripterin (Celastrol) is a natural product, a proteasome inhibitor that inhibits the pancreatic rennet-like activity of the 20S proteasome (IC50=2.5 μM). Tripterin has anti-inflammatory, anti-infectious, and immunomodulatory properties.

Gallocatechin gallate is a flavonoid compound isolated from South American snake plant, with antiviral activity by inhibiting the entry and release stages of pseudorabies virus replication.

(-)-Epiafzelechin is a COX inhibitor with antioxidant and anti-inflammatory activity, osteoprotective effects in a mature ovariectomized mouse model, ability to stimulate osteoblast activity and inhibit osteoclast activity.

trans-Nerolidol is a sesquiterpene alcohol isolated from the above-ground parts of the Saharan Valerian plant with antifungal activity. trans-Nerolidol inhibits cell proliferation in a dose-dependent manner, and induces cell cycle arrest in the G1 phase.

(+)-Afzelechin (Afzelechin) is isolated from Eysenhardtia subcoriacea. It is an α-glucosidase activity inhibitor, offering neuroprotective effects against glutamate-induced neurotoxicity in HT22 cells and improving reduced glutathione levels in rat pancreas homogenates.

3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal is a natural product for research related to life sciences. The catalog number is TN6641 and the CAS number is 60026-28-0.

Mupinensisone is a natural product of Celastrus, Celastraceae. The catalog number is TN5951 and the CAS number is 152253-67-3. Mupinensisone can be used as a reference standard.

Lupeol caffeate has anti-malarial activity.

12-Oleanene-3,6-diol has antitumor activity, it can induce apoptosis and has inhibition effect on the proliferation in RKO cell line.

28-Hydroxy-3-oxoolean-12-en-29-oic acid is a natural product for research related to life sciences. The catalog number is TMA1182 and the CAS number is 381691-22-1.

Olean-12-ene-3,11-diol is a natural product for research related to life sciences. The catalog number is TN4701 and the CAS number is 5282-14-4.

Celaphanol A shows moderate inhibition in both NF-κB activation and nitric oxide production, suggests that it is a possible inhibitor of the NF-kappaB pathway and has antiinflammatory activity.