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Achariaceae

Achariaceae is a family of flowering plants within the order Malpighiales, primarily distributed in tropical regions. Members produce diverse secondary metabolites including glucosinolates, flavonoids, alkaloids, and cyanogenic glycosides, which serve as chemical defenses against herbivores. In biomedical research, Achariaceae is studied for its antimicrobial, anti-inflammatory, and cytotoxic properties, although many species remain poorly characterized. Its chemical defense diversity makes it relevant for studying plant–insect interactions and natural product evolution in tropical ecosystems.

  • Nigracin
    TN465618463-25-7
    Nigracin is a natural product for research related to life sciences. The catalog number is TN4656 and the CAS number is 18463-25-7.
    • $798
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  • (Rac)-Hydnocarpin
    Hydnocarpin
    TN233451419-48-8
    (Rac)-Hydnocarpin is a natural flavonolignan derived from the flowers of Pueraria lobata that demonstrates strong cytotoxic effects against multiple ovarian cancer cell lines while maintaining minimal toxicity toward normal ovarian surface epithelial cells. (Rac)-Hydnocarpin triggers intrinsic apoptotic signaling through activation of caspase-9 and caspase-3 with limited involvement of caspase-8, driven by reactive oxygen species generation as a dominant mediator of apoptosis. (Rac)-Hydnocarpin additionally reprograms tumor-associated immune cells by reducing M2 macrophage markers and pro-tumoral mediators including matrix metalloproteinase-2/9, C–C motif chemokine ligand 5, transforming growth factor-β, and vascular endothelial growth factor, while enhancing macrophage phagocytosis, reinforcing its role as a multifunctional anticancer agent.
    • $44
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  • Homaloside D
    TN4218149155-19-1
    Homaloside D has antiplasmodial activity.
    • $2,278
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