3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats.

Hydrocinchonine is reported to have multidrug resistance reversal activity, which can weaken drug resistance by inhibiting the function of P-gp and possibly affecting its expression. In MES-SA/DX5 cells, the combination of Hydrocinchonine and Paclitaxel can enhance the apoptosis.