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Euphorbia

Phorbol 12-myristate 13-acetate
PMA
TQ019816561-29-8
Phorbol 12-myristate 13-acetate (PMA) is a natural phorbol ester that acts as an activator of PKC, SphK, and NF-κB, and is commonly used to induce differentiation of THP-1 cells and establish dermatitis models.
  • $44
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Ingenol-3,4,5,20-diacetonide
Ingenol-3,4:5,20-diacetonide
TN176577573-44-5
Ingenol-3,4,5,20-diacetonide, a natural product isolated from the sap of the Euphorbia plant, exhibits a wide range of biological activities, including anti-tumor, anti-inflammatory, and immunomodulatory effects.
  • $123
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Kaempferol 3-O-β-D-glucuronide
Kaempferol-3-O-glucuronide, Kaempferol-3-glucuronide, Kaempferol-3-beta-O-glucuronide
TN181822688-78-4
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) exhibits antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells.
  • $93
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Ingenol mebutate
PEP005, Ingenol 3-Angelate
TN104775567-37-2
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.
  • $64
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euphol
T5737514-47-6
Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
  • $84
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Ingenol
(-)-Ingenol
T5S201730220-46-3
1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. 3. Ingenol is a weak PKC activator and possesses important anticancer activity.
  • $44
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Epitaraxerol
Isotaraxerol, 3α-Taraxerol
TN397820460-33-7
Epitaraxerol (Isotaraxerol) is an antifungal natural product with moderate antibacterial activity against Candida albicans.
  • $338
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Kansuinine A
TN437957701-86-7
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
  • $167
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(E)-Ferulic acid
trans-Ferulic acid, (E)-Coniferic acid
T5679537-98-4
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.t(E)-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • $29
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Euphorbia Factor L2
euphorbiafactor L2
T5798218916-51-9
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
  • $68
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17-Hydroxyisolathyrol
TN119693551-00-9
γ-L-Glutamyl-L-alanine consists of γ-glutamate and alanine, and is a substrate for CRF21 (γ-glutamyl cyclotransferase, GGCT), a proteolytic breakdown product of larger proteins.γ-L-Glutamyl-L-alanine is a positive regulator of calcium-sensitive receptor (CaR) function.
  • $42
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Ingenol-5,20-acetonide-3-O-angelate
Ingenol 5,20-acetonide 3-angelate, Ingenol 3-angelate 5,20-acetonide
TQ031687980-68-5
Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide 3-angelate) is a natural product.
  • $79
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Tirucallol
TN1006514-46-5
Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.
  • $89
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Euphorbia factor L8
TN1635218916-53-1
Euphorbia factor L8 is a diterpene from Morinda citrifolia seeds.
  • $64
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20-O-Acetylingenol-3-angelate
Euphorbia factor Pe1
TQ009982425-35-2
20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, antifungal and antioxidant effects.
  • $172
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Lathyrol
T3S201934420-19-4
1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.
  • $42
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Euphorbia factor L1
Euphorbiasteroid
T2S041076376-43-7
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, anti-osteoclastogenic, and multidrug-resistant regulatory effects.
  • $33
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5,15-Diacetyl-3-benzoyllathyrol
Euphorbia factor L3
T4S2014218916-52-0
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability.
  • $33
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Euphorbia factor L7a
TN163393550-94-8
Euphorbia factor L7a is a diterpene found in the seeds of Morinda citrifolia.
  • $84
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Euphorbia factor L7b
TN163493550-95-9
Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.
  • $64
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5-hydroxythalidomide
5,8,9,14-Tetraacetoxy-3-benzoyloxy-10,15-dihydroxypepluane
TN3098219916-77-5
5-hydroxythalidomide is a natural product for research related to life sciences. The catalog number is TN3098 and the CAS number is 219916-77-5.
  • $660
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Simiarenone
TN50252318-78-7
Simiarenone is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN5025 and the CAS number is 2318-78-7. Simiarenone can be used as a reference standard.
  • $550
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Phorbol 13-acetate
TN476832752-29-7
Phorbol 13-acetate is a natural product for research related to life sciences. The catalog number is TN4768 and the CAS number is 32752-29-7.
  • $590
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Euphohelioscopin A
TN559387064-61-7
Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity
  • $660
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