Toddalosin is a natural product of Toddalia, Rutaceae. The catalog number is TN5150 and the CAS number is 137182-37-7. Toddalosin can be used as a reference standard.
Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB. Braylin is also a phosphodiesterase-4 inhibitor, it could represent an ideal prototype of glucocorticoid receptor ligand, able to induce synergic immunomodulatory effects.
7-Geranyloxy-5-methoxycoumarin is a naturally occurring compound found in many plants, including the bark of the red maple tree. It has been shown to have anti-inflammatory, antioxidant and anti-tumor properties.
8-Geranyloxy-5,7-dimethoxycoumarin is a natural product of Toddalia, Rutaceae. The catalog number is TN3277 and the CAS number is 1228175-65-2. 8-Geranyloxy-5,7-dimethoxycoumarin can be used as a reference standard.
3-(1,1-Dimethylallyl)-8-hydroxy-7-methoxycoumarin is a natural product for research related to life sciences. The catalog number is TN2847 and the CAS number is 61899-42-1.
Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negative pathogen and yeast with MICs of 256 to ≥1024 ug/ml.
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1 2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis inducer in U-937 cells.