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T0830	Bithionol	Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause seri...
T2244	ESI-09	ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is3.2 and 1.4 μM, respectively.
T6536	HJC0350	HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.
TN1266	3-O-Methylquercetin	3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phos...
TN1334	7-O-Methylrosmanol	7-O-methylrosmanol can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute...
TN1504	Citreorosein	Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of bot...
TN1841	Kushenol A	Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kush...
TN2092	Polygalasaponin XXXI	Onjisaponin F(Polygalasaponin XXXI) acts non-competitively against cyclic AMP phosphodiesterase, like papaverine; it also exhibits a prolongation effect on hexo...
TN2230	Soyasaponin Ba	Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher an...
TN1620	Eriocalyxin B	Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a can...
TN1027	beta-Amyrin	beta-Amyrin has antiviral, hepatoprotective, antinociceptive, anti-inflammatory, it retard acute inflammation in rat model of periodontitis.
TN1121	Evocarpine	Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
TN1420	Bacopaside I	Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/P...
TN2039	Panaxydol	Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 M...

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