TN2039 |
Panaxydol
|
72800-72-7
|
98%
|
|
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MA...
|
TN1841 |
Kushenol A
|
99217-63-7
|
98%
|
|
Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushe...
|
TN4433 |
Licoarylcoumarin
|
125709-31-1
|
98%
|
|
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st...
|
TN2092 |
Polygalasaponin XXXI
|
79103-90-5
|
98%
|
|
Onjisaponin F(Polygalasaponin XXXI) acts non-competitively against cyclic AMP phosphodiesterase, like papaverine; it also exhibits a prolongation effect on hexob...
|
TN4051 |
Fargesone B
|
116424-70-5
|
98%
|
|
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
|
TN1504 |
Citreorosein
|
481-73-2
|
98%
|
|
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
|
TN4277 |
Isocupressic acid
|
1909-91-7
|
98%
|
|
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
|
TMA2419 |
Catalponol
|
34168-56-4
|
98%
|
|
Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the inc...
|
TN4317 |
Isopedicin
|
4431-42-9
|
98%
|
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
|
TN3013 |
4,5-Dimethoxycanthin-6-one
|
18110-87-7
|
98%
|
|
4,5-Dimethoxycanthin-6-one has antibacterial actiyity, it exhibits inhibition against Staphylococcus aureus and its drug-resistant strains. 4,5-Dimethoxycanthin-...
|
TN4178 |
Gyrophoric acid
|
548-89-0
|
98%
|
|
Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton...
|
T13983 |
0990CL
|
511514-03-7
|
98%
|
|
0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP reg...
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
TN3882 |
Dodoviscin A
|
1372527-25-7
|
98%
|
|
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
|
TN4551 |
Methyl orsellinate
|
3187-58-4
|
98%
|
|
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus...
|
T64355 |
TDI-10229
|
2810887-45-5
|
98%
|
|
TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemica...
|
TN3379 |
Allocryptopine
|
24240-04-8
|
98%
|
|
Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cyto...
|
TMA0003 |
Trans-caffeic acid
|
501-16-6
|
98%
|
|
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
|
TN2918 |
3-Acetoxy-8(17),13E-labdadien-15-oic acid
|
63399-37-1
|
98%
|
|
ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
|
TMA1944 |
Protopine hydrochloride
|
6164-47-2
|
98%
|
|
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell...
|