cAMP

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. It should not be confused with 5'-AMP-activated protein kinase (AMP-activated protein kinase).

Cat. No.	Product name	CAS No.	Purity
T67965	Torbafylline	105102-21-4	98%
T67965	Torbafylline, a xanthine derivative, is a phosphodiesterase (PDE) inhibitor that attenuates burn-induced protein hydrolysis in rat skeletal muscle through activa...
T13983	0990CL	511514-03-7	98%
T13983	0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP reg...
T22466	1,3-Dipropyl-8-phenylxanthine	85872-53-3	98%
T22466	1,3-Dipropyl-8-phenylxanthine acts as an adenosine antagonist, is an oxypurine, acts as an insecticide and pest control agent, and has an inhibitory effect on el...
TMA2419	Catalponol	34168-56-4	98%
TMA2419	Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the inc...
TN4433	Licoarylcoumarin	125709-31-1	98%
TN4433	Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st...
TN4277	Isocupressic acid	1909-91-7	98%
TN4277	Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
TMA1944	Protopine hydrochloride	6164-47-2	98%
TMA1944	Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell...
TN4317	Isopedicin	4431-42-9	98%
TN4317	Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
TN3607	Catalpalactone	1585-68-8	98%
TN3607	Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264....
TN4551	Methyl orsellinate	3187-58-4	98%
TN4551	Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus...
TN1841	Kushenol A	99217-63-7	98%
TN1841	Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushe...
TN2918	3-Acetoxy-8(17),13E-labdadien-15-oic acid	63399-37-1	98%
TN2918	ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
TMA1122	N-Feruloylserotonin	68573-23-9	98%
TMA1122	Moschamine is a very potent compound that is able to inhibit COX-I by 58% and COX-II by 54%, at the concentration of 0.1 μmol L⁻1, it may suppress cAMP for...
TN4489	Manassantin A	88497-87-4	98%
TN4489	Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
TN4178	Gyrophoric acid	548-89-0	98%
TN4178	Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton...
TN3882	Dodoviscin A	1372527-25-7	98%
TN3882	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
TN2039	Panaxydol	72800-72-7	98%
TN2039	Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MA...
TN1504	Citreorosein	481-73-2	98%
TN1504	Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
TN4051	Fargesone B	116424-70-5	98%
TN4051	Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
TMA0003	Trans-caffeic acid	501-16-6	98%
TMA0003	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...