Search Result

Search Results for " virus protease "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by ...
T6327	Tubacin		Virus Protease , HDAC
	Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.		Virus Protease , HDAC
T13397	ZINC03129319		Virus Protease
	ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease.		Virus Protease
T14044	4E2RCat		PERK
	4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM).		PERK
T1848	Dynasore	Dynamin Inhibitor I	Dynamin , Virus Protease , Autophagy , HSV
	Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, ...		Dynamin , Virus Protease , Autophagy , HSV
T2244	ESI-09		cAMP , Virus Protease
	ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.		cAMP , Virus Protease
T25268	Coblopasvir		Others
	Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.		Others
T1307	Carmofur	HCFU	Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
T1883	Des(benzylpyridyl) Atazanavi		HIV Protease
	The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.		HIV Protease
T8936	Proteinase K	proteinase K for tritirachium album,Protease K	Others
	Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...		Others
T6309	AZ960	AZ 960	Apoptosis , Virus Protease , JAK , Parasite
	AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).		Apoptosis , Virus Protease , JAK , Parasite
T7779	Nelfinavir	AG1341	HIV Protease
	Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.		HIV Protease
T1954	SRPIN340	SRPK inhibitor	Virus Protease , Serine/threonin kinase
	SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).		Virus Protease , Serine/threonin kinase
T6605	NH125		CaMK , Virus Protease , PKA , Antibacterial , PKC , Autophagy , Antifungal
	NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
T4197	HZ-1157	HZ1157,DHFR-inhibitor	HCV Protease
	HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.		HCV Protease
T8371	ML188		Virus Protease , SARS-CoV
	ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.		Virus Protease , SARS-CoV
T7366	NGI-1	ML414	Virus Protease
	NGI-1 (ML414) is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.		Virus Protease
T4547	Grazoprevir	MK-5172	HCV Protease , SARS-CoV
	Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ...		HCV Protease , SARS-CoV
T2616	PIK-93	PIK 93	ATM/ATR , DNA-PK , Virus Protease , PI3K , Carbonic Anhydrase , PI4K , mTOR , HSV
	PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T1822	Clemizole		HCV Protease , Histamine Receptor
	Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.		HCV Protease , Histamine Receptor
T5126	Glecaprevir	ABT-493	HCV Protease , SARS-CoV
	Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).		HCV Protease , SARS-CoV
T12711	Retro-2 cycl	RN 1-001	Virus Protease
	Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 160 μM, respectively),with antiviral agent.		Virus Protease
T25268L	Coblopasvir dihydrochloride	Coblopasvir dihydrochloride(1312608-46-0 Free base)	HCV Protease
	Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.		HCV Protease
T7903	Saquinavir	Ro 31-8959	SARS-CoV , HIV Protease
	Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.		SARS-CoV , HIV Protease
T9716	Ensitrelvir	S-217622	SARS-CoV
	Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM.		SARS-CoV
T12437	PF429242 dihydrochloride		S1P Receptor
	PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM).		S1P Receptor
T4474	Asunaprevir	BMS-650032	HCV Protease , SARS-CoV
	Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.		HCV Protease , SARS-CoV
T6370	AEBSF hydrochloride	AEBSF HCl,Pefabloc SC	Thrombin , Serine Protease , Influenza Virus
	AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.		Thrombin , Serine Protease , Influenza Virus
T0495	Aminothiazole	2-Aminothiazole,2-Thiazolylamine	Virus Protease , Antibacterial , Antibiotic , Antifungal
	Aminothiazole (2-Aminothiazole), a thyroid inhibitor, displays antibacterial activity.
T1822L	Clemizole hydrochloride		HCV Protease , Histamine Receptor
	Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding.		HCV Protease , Histamine Receptor
T0939	Phenytoin	Diphenylhydantoin,5,5-Diphenylhydantoin	Virus Protease , Sodium Channel
	Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...		Virus Protease , Sodium Channel
T0220	Foscarnet sodium	Phosphonoformate	Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
	Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T6001	Nelfinavir Mesylate	Viracept,Nelfin,AG1343,AG 1343 Mesylate	HIV Protease
	Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).		HIV Protease
T5886	4-Phenylbutyric acid	Benzenebutyric acid	Virus Protease , HDAC
	4-Phenylbutyric acid (Benzenebutyric acid) is an inhibitor of HDAC,and is an antineoplastic agent.		Virus Protease , HDAC
T5158	N-Desmethylclozapine	Desmethylclozapine,Normethylclozapine,Norclozapine	Virus Protease , Dopamine Receptor , 5-HT Receptor , Opioid Receptor , AChR , Drug Metabolite
	N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
T2324	Darunavir	TMC114	HIV Protease
	Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other AN...		HIV Protease
T8328	STING agonist-1	G10	Virus Protease , STING
	STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.		Virus Protease , STING
T21900	ML-336		Others
	ML-336 is an inhibitor of of the Venezuelan equine encephalitis virus (VEEV) strain TC-83.		Others
T1623	Lopinavir	ABT-378	SARS-CoV , HIV Protease
	Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr...		SARS-CoV , HIV Protease
T23004	ML-SA1	Mucolipin synthetic agonist 1	Others , TRP/TRPV Channel
	ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV...		Others , TRP/TRPV Channel
T4686	Simeprevir	TMC435,TMC-435350,Olysio	HCV Protease , SARS-CoV
	Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.		HCV Protease , SARS-CoV
T3359	Aprotinin	Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others , Serine Protease , Influenza Virus , Proteasome
	Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...		Others , Serine Protease , Influenza Virus , Proteasome
T9567	Samatasvir	ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.		HCV Protease
T4988	Boceprevir	SCH 503034,EBP 520	HCV Protease , SARS-CoV
	Boceprevir (SCH 503034) is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay.		HCV Protease , SARS-CoV
T22394	Paritaprevir	ABT450,ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.		HCV Protease
T6388	Amprenavir	141W94,Prozei,KVX-478,VX-478	SARS-CoV , HIV Protease
	Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.		SARS-CoV , HIV Protease
T5013	Brequinar	Bipenquinate,NSC 368390,DUP785	Virus Protease , Dehydrogenase , DNA/RNA Synthesis
	Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.		Virus Protease , Dehydrogenase , DNA/RNA Synthesis
T1525	Ritonavir	RTV,Abbott 84538,A 84538,ABT 538	Apoptosis , SARS-CoV , HIV Protease
	Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cy...		Apoptosis , SARS-CoV , HIV Protease
T0825	Ebselen	SPI-1005,PZ-51,CCG-39161	Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
	Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T6190	Telaprevir	VX-950,LY-570310,Incivek,MP-424	HCV Protease , SARS-CoV
	Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).		HCV Protease , SARS-CoV

Compounds

Hepatitis Virus C NS3 Protease Inhibitor 2

Target: Virus Protease, HDAC

ZINC03129319

T13397

Synonym:

Target: Virus Protease

Synonym: Dynamin Inhibitor I

Target: Dynamin, Virus Protease, Autophagy, HSV

ESI-09

T2244

Synonym:

Target: cAMP, Virus Protease

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

Des(benzylpyridyl) Atazanavi

T1883

Synonym:

Target: HIV Protease

Proteinase K

T8936

Synonym: proteinase K for tritirachium album,Protease K

Target: Apoptosis, Virus Protease, JAK, Parasite

Nelfinavir

T7779

Synonym: AG1341

Target: HIV Protease

SRPIN340

T1954

Synonym: SRPK inhibitor

Target: Virus Protease, Serine/threonin kinase

NH125

T6605

Synonym:

Target: CaMK, Virus Protease, PKA, Antibacterial, PKC, Autophagy, Antifungal

HZ-1157

T4197

Synonym: HZ1157,DHFR-inhibitor

Target: HCV Protease

ML188

T8371

Synonym:

Target: Virus Protease, SARS-CoV

NGI-1

T7366

Synonym: ML414

Target: Virus Protease

Grazoprevir

T4547

Synonym: MK-5172

Target: HCV Protease, SARS-CoV

PIK-93

T2616

Synonym: PIK 93

Target: ATM/ATR, DNA-PK, Virus Protease, PI3K, Carbonic Anhydrase, PI4K, mTOR, HSV

Clemizole

T1822

Synonym:

Target: HCV Protease, Histamine Receptor

Glecaprevir

T5126

Synonym: ABT-493

Target: HCV Protease, SARS-CoV

Retro-2 cycl

T12711

Synonym: RN 1-001

Target: Virus Protease

Coblopasvir dihydrochloride

T25268L

Synonym: Coblopasvir dihydrochloride(1312608-46-0 Free base)

Target: HCV Protease

Saquinavir

T7903

Synonym: Ro 31-8959

Target: SARS-CoV, HIV Protease

PF429242 dihydrochloride

Target: HCV Protease, SARS-CoV

AEBSF hydrochloride

T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

Aminothiazole

T0495

Synonym: 2-Aminothiazole,2-Thiazolylamine

Target: Virus Protease, Antibacterial, Antibiotic, Antifungal

Clemizole hydrochloride

T1822L

Synonym:

Target: HCV Protease, Histamine Receptor

Phenytoin

T0939

Synonym: Diphenylhydantoin,5,5-Diphenylhydantoin

Target: Virus Protease, Sodium Channel

Foscarnet sodium

T0220

Synonym: Phosphonoformate

Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis

Nelfinavir Mesylate

T6001

Synonym: Viracept,Nelfin,AG1343,AG 1343 Mesylate

Target: HIV Protease

4-Phenylbutyric acid

T5886

Synonym: Benzenebutyric acid

Target: Virus Protease, HDAC

N-Desmethylclozapine

T5158

Synonym: Desmethylclozapine,Normethylclozapine,Norclozapine

Target: Virus Protease, Dopamine Receptor, 5-HT Receptor, Opioid Receptor, AChR, Drug Metabolite

Darunavir

T2324

Synonym: TMC114

Target: HIV Protease

STING agonist-1

T8328

Synonym: G10

Target: Virus Protease, STING

Target: SARS-CoV, HIV Protease

ML-SA1

T23004

Synonym: Mucolipin synthetic agonist 1

Target: Others, TRP/TRPV Channel

Simeprevir

T4686

Synonym: TMC435,TMC-435350,Olysio

Target: HCV Protease, SARS-CoV

Aprotinin

T3359

Synonym: Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Samatasvir

T9567

Synonym: ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719

Target: HCV Protease

Boceprevir

T4988

Synonym: SCH 503034,EBP 520

Target: HCV Protease, SARS-CoV

Paritaprevir

T22394

Synonym: ABT450,ABT-450,Veruprevir

Target: HCV Protease

Amprenavir

T6388

Synonym: 141W94,Prozei,KVX-478,VX-478

Target: SARS-CoV, HIV Protease

Brequinar

T5013

Synonym: Bipenquinate,NSC 368390,DUP785

Target: Virus Protease, Dehydrogenase, DNA/RNA Synthesis

Ritonavir

T1525

Synonym: RTV,Abbott 84538,A 84538,ABT 538

Target: Apoptosis, SARS-CoV, HIV Protease

Ebselen

T0825

Synonym: SPI-1005,PZ-51,CCG-39161

Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease

Telaprevir

T6190

Synonym: VX-950,LY-570310,Incivek,MP-424

Target: HCV Protease, SARS-CoV

Cat No.	Product Name	Synonyms	Targets
TMO2787	Anthraquinone	dioxoanthracene,Anthradione,anthracenedione	Virus Protease
	Anthraquinone (Anthradione)s are the main active constituents in herbs often used to relieve constipation.		Virus Protease
T5666	Dipotassium glycyrrhizinate		Virus Protease
	Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.		Virus Protease
T2875	Angelicin	Isopsoralen	Apoptosis , Virus Protease , Antiviral
	Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.		Apoptosis , Virus Protease , Antiviral
T2741	Glycyrrhizic acid	Glycyrrhizin	Virus Protease , Dehydrogenase , MAO
	Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.		Virus Protease , Dehydrogenase , MAO
T2926	Schizandrin A		P450 , Virus Protease , Autophagy
	Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μM and a Ki of 5.83 μM.		P450 , Virus Protease , Autophagy
T0122	Bergenin	Cuscutin,Bengenin	Apoptosis , IL Receptor , Virus Protease , TNF , NF-κB , Antibacterial , NOD , Autophagy , Antifungal
	Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T0254	Probucol	DH-581	Virus Protease , ABC , Lipid
	Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.		Virus Protease , ABC , Lipid
T0433	Artesunate	WR-256283	Virus Protease , Ferroptosis , STAT , Parasite
	Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Heal...		Virus Protease , Ferroptosis , STAT , Parasite
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T4850	PCL 016	2-Picolinic acid	Virus Protease , Endogenous Metabolite
	PCL 016 (2-Picolinic acid) is a topical antiviral agent, which inhibits adenovirus replication in rabbit.		Virus Protease , Endogenous Metabolite
T6S0095	Genkwanin	7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether	Virus Protease
	1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance pr...		Virus Protease
T1717	Alpha-Mangostin	α-Mangostin,Mangostin	Apoptosis , Virus Protease , Dehydrogenase , Reactive Oxygen Species , Antibacterial , Antifungal
	alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
T2A2498	L-Lysine	Aminutrin,Lysine Acid,lysine	Virus Protease , Endogenous Metabolite , Antifection
	L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active again...		Virus Protease , Endogenous Metabolite , Antifection
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T3717	Hinokitiol	4-Isopropyltropolone,β-thujaplicin	DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
	Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T5S1923	Schisandrin C	Schizandrin-C,Wuweizisu-C	Apoptosis , Others , Virus Protease
	Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.		Apoptosis , Others , Virus Protease
T8071	L-Lysine hydrochloride	Lysine hydrochloride	Virus Protease
	L-Lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, reducing diabetes-related illnesses, increasing calcium absorption and improving gut health.		Virus Protease
T0800	Danthron	Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol	Virus Protease , Antibacterial , AMPK , Autophagy
	Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.		Virus Protease , Antibacterial , AMPK , Autophagy
TN1202	(-)-α-Pinene	(1S)-(-)-Alpha-Pinene	Virus Protease , GABA Receptor , Endogenous Metabolite , Antibacterial
	(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directl...
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T0011	2-Phenylethanol	Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol	Others , Virus Protease , Antibacterial , Antibiotic
	2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.		Others , Virus Protease , Antibacterial , Antibiotic
T2774	Lycorine hydrochloride	Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride	Virus Protease , HCV Protease , Antibacterial , Autophagy
	Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
T3759	3,4-Dimethoxycinnamic acid	Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid	Apoptosis , Virus Protease , Reactive Oxygen Species
	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated...		Apoptosis , Virus Protease , Reactive Oxygen Species
T2732	(-)-Epicatechin gallate	(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG	Virus Protease , COX , Autophagy
	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin...		Virus Protease , COX , Autophagy
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
TN1059	Ganoderic acid B		IL Receptor , HIV Protease , JAK , STAT
	Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an...		IL Receptor , HIV Protease , JAK , STAT
TN4109	Ganolucidic acid A		HIV Protease
	Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of...		HIV Protease
TMA1012	Ganoderiol F		Androgen Receptor , HIV Protease , Autophagy
	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced...		Androgen Receptor , HIV Protease , Autophagy
T72508	Palmatine hydroxide
	Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhib...

Natural Products

Anthraquinone

TMO2787

Synonym: dioxoanthracene,Anthradione,anthracenedione

Target: Virus Protease

Dipotassium glycyrrhizinate

T5666

Synonym:

Target: Virus Protease

Angelicin

T2875

Synonym: Isopsoralen

Target: Apoptosis, Virus Protease, Antiviral

Glycyrrhizic acid

T2741

Synonym: Glycyrrhizin

Target: Virus Protease, Dehydrogenase, MAO

Schizandrin A

T2926

Synonym:

Target: P450, Virus Protease, Autophagy

Bergenin

T0122

Synonym: Cuscutin,Bengenin

Target: Apoptosis, IL Receptor, Virus Protease, TNF, NF-κB, Antibacterial, NOD, Autophagy, Antifungal

Probucol

T0254

Synonym: DH-581

Target: Virus Protease, ABC, Lipid

Artesunate

T0433

Synonym: WR-256283

Target: Virus Protease, Ferroptosis, STAT, Parasite

Palmatine chloride

T2718

Synonym:

Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase

Palmatine

T5S0802

Synonym: Berbericinine,Burasaine

Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase

PCL 016

T4850

Synonym: 2-Picolinic acid

Target: Virus Protease, Endogenous Metabolite

Genkwanin

T6S0095

Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether

Target: Virus Protease

alpha-Mangostin

T1717

Synonym: α-Mangostin,Mangostin

Target: Apoptosis, Virus Protease, Dehydrogenase, Reactive Oxygen Species, Antibacterial, Antifungal

L-Lysine

T2A2498

Synonym: Aminutrin,Lysine Acid,lysine

Target: Virus Protease, Endogenous Metabolite, Antifection

Theaflavin 3,3'-digallate

T5429

Synonym: 8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Hinokitiol

T3717

Synonym: 4-Isopropyltropolone,β-thujaplicin

Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2

Schisandrin C

T5S1923

Synonym: Schizandrin-C,Wuweizisu-C

Target: Apoptosis, Others, Virus Protease

L-Lysine hydrochloride

T8071

Synonym: Lysine hydrochloride

Target: Virus Protease

Danthron

T0800

Synonym: Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol

Target: Virus Protease, Antibacterial, AMPK, Autophagy

(-)-α-Pinene

TN1202

Synonym: (1S)-(-)-Alpha-Pinene

Target: Virus Protease, GABA Receptor, Endogenous Metabolite, Antibacterial

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

2-Phenylethanol

T0011

Synonym: Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol

Target: Others, Virus Protease, Antibacterial, Antibiotic

Lycorine hydrochloride

T2774

Synonym: Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride

Target: Virus Protease, HCV Protease, Antibacterial, Autophagy

3,4-Dimethoxycinnamic acid

T3759

Synonym: Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid

Target: Apoptosis, Virus Protease, Reactive Oxygen Species

(-)-Epicatechin gallate

T2732

Synonym: (−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG

Target: Virus Protease, COX, Autophagy

Lycorine

T3324

Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Ganoderic acid B

TN1059

Synonym:

Target: IL Receptor, HIV Protease, JAK, STAT

Ganolucidic acid A

TN4109

Synonym:

Target: HIV Protease

Ganoderiol F

TMA1012

Synonym:

Target: Androgen Receptor, HIV Protease, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B...
TMPH-00060	ApNPV Viral cathepsin Protein (His & Myc)	ApNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system.
TMPH-00310	Bovine viral diarrhea virus (strain SD-1) Genome polyprotein (E. coli, His)	BVDV	E. coli
	Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. Once released, plays a role in the inhibition of host innate immune response by interacting with host IR...
TMPH-00309	Bovine viral diarrhea virus (strain SD-1) Genome polyprotein (His)	BVDV	Baculovirus
	Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. Once released, plays a role in the inhibition of host innate immune response by interacting with host IR...
TMPH-02238	TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc)	Human	HEK293
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPH-02235	TMPRSS2 Protein, Human, Recombinant (Cell-Free, His)	Human	in vitro E. coli expression system
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPY-01463	USP7 Protein, Human, Recombinant (aa 208-560, His & GST)	Human	Baculovirus-Insect Cells
	Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPY-01464	USP7 Protein, Human, Recombinant (aa 208-560)	Human	Baculovirus-Insect Cells
	Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPY-01465	USP7 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPH-01055	Caspase-1 Protein, Human, Recombinant (HA)	Human	E. coli
	Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well ...
TMPY-00818	Granzyme H/GZMH Protein, Human, Recombinant (His)	Human	HEK293
	Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPH-00385	Chikungunya virus (strain S27-African prototype) Non-structural protein 4 (His)	CHIKV	E. coli
	Inactive precursor of the viral replicase, which is activated by cleavages carried out by the viral protease nsP2.; The early replication complex formed by the polyprotein P123 and nsP4 synthesizes minus-strand RNAs. As ...