Search Result

Search Results for " vero "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T60014	SHEN26		Antiviral
	SHEN26 has antiviral activity and can be used in research on the treatment of viral infections.		Antiviral
T0711	Niclosamide	BAY2353,Niclocide	Antibiotic , STAT , Parasite
	Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.		Antibiotic , STAT , Parasite
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T1784	Everolimus	RAD001,SDZ-RAD	Apoptosis , Others , mTOR , Autophagy
	Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.		Apoptosis , Others , mTOR , Autophagy
T35048	Verofylline	CK 0383,Verofilina,CK-0383,Verofyllinum,CK0383	PDE
	Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the treatment of asthma disease research obesity.		PDE
T60924	Verosudil	AR-12286	ROCK
	Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular ...		ROCK
T35051	Vetiverol	Lignolia,Vetivenol
	Vetiverol is a fragrance ingredient.
T125858	Priverosaponin B 22-acetate
	Priverosaponin B 22-acetate is a useful organic compound for research related to life sciences. The catalog number is T125858 and the CAS number is 144379-37-3.
T125411	Acetovanillone primeveroside
	Acetovanillone primeveroside is a useful organic compound for research related to life sciences. The catalog number is T125411 and the CAS number is 20226-67-9.
T126071	Benzyl b-primeveroside
	Benzyl b-primeveroside is a useful organic compound for research related to life sciences. The catalog number is T126071 and the CAS number is 130622-31-0.
T38044	Reveromycin B
	Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against...
T37423	Reveromycin D
	Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μ...
T124741	Veronicoside
	Veronicoside is a useful organic compound for research related to life sciences. The catalog number is T124741 and the CAS number is 50981-09-4.
T130388	4-(2-Nitroethyl)phenyl primeveroside
	4-(2-Nitroethyl)phenyl primeveroside is a useful organic compound for research related to life sciences and the catalog number is T130388.
T70735	Verosudil hydrochloride
	Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfolia...
T33175	Mandelonitrile primeveroside
	Mandelonitrile primeveroside is isolated from the Australian rainforest tree Clerodendrum grayi.
T8498	EIDD-1931	Beta-d-N4-hydroxycytidine	Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...		Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
T8501	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide		Influenza Virus
	3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into hos...		Influenza Virus
T7055	Bz-RS-ISer(3-Ph)-Ome	Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate	Others , HIV Protease
	Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...		Others , HIV Protease
T1307	Carmofur	HCFU	Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
T12837	SARS-CoV-IN-1		Others
	SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor(EC50 of 4.9 μM in Vero cells).		Others
T40207	SARS-CoV-2-IN-7
	SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 value of 844 nM.
T79329	SARS-CoV-2-IN-56		SARS-CoV
	SARS-CoV-2-IN-56 (Compound 63) is a SARS-CoV-2 inhibitor with antiviral activity, demonstrating inhibition of the virus in Vero E6 cells with an IC50 of 0.7 μM [1].		SARS-CoV
T79328	SARS-CoV-2-IN-54		SARS-CoV
	SARS-CoV-2-IN-54 (Compound 2), a SARS-CoV-2 inhibitor, exhibits antiviral activity by impeding the virus in Vero E6 cells with an inhibitory concentration (IC50) of 21.4 μM [1].		SARS-CoV
T79462	SARS-CoV-2 3CLpro-IN-14		SARS-CoV
	SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active inhibitor of SARS-CoV-2 3CLpro, demonstrating potent anti-SARS-CoV-2 properties with an EC50 of 0.18 μM and exhibits minimal cytotoxicity, having a CC50 greater ...		SARS-CoV
T62066	Antitubercular agent-29
	Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor. Antitubercular agent-29 exhibits MIC of 0.03 μg/mL against drug-susceptible (DS)-Mtb strains, MIC of 0.03...
T72718	SARS-CoV-2-IN-36
	SARS-CoV-2-IN-36 is a potent inhibitor of SARS-CoV-2 Mpro (SARS-CoV), demonstrating an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. This compound exhibits antiviral activity against SARS-CoV-2 variants UC-107...
T81209	SARS-CoV-2-IN-62		SARS-CoV
	SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1].		SARS-CoV
T61170	Antibacterial agent 96
	Antibacterial Agent 96 (Compound 4k) is a potent antibacterial and antitubercular compound effective against both drug-susceptible and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. However, it...
T78675	Neuraminidase-IN-13		Influenza Virus
	Neuraminidase-IN-13 (Compound 10), a neuraminidase inhibitor exhibiting antiviral activity, demonstrates significant inhibition of NDV infection in Vero cells with minimal cytotoxicity by impeding the release of viral pa...		Influenza Virus
T61853	Antimycobacterial agent-1
	Antimycobacterial agent-1 (compound 33) demonstrates potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimal inhibitory concentration (MIC) value of 1 μg/ml. Notably, antimycobacterial ...
T72519	Niclosamide sodium	BAY2353 sodium
	Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compoun...
T63598	DENV-IN-4
	DENV-IN-4 is a potent inhibitor of DENV (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). The antiviral effect was demonstrated by the concentration-dependent reduction of DENV2 expression and the inhibition of RNA-depende...
T36435	SP 10
	Peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). Inhibit...
T78963	Antileishmanial agent-16		Parasite
	Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) and amastigotes (IC50 = 0.81 µM), while maintaining a favorable safety p...		Parasite
T60906	Miaosporone A
	Miaosporone A is an angucyclic quinone which shows cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells. Miaosporone A has antibacterial activity against Mycobacterium tuberculos...
T81208	SARS-CoV-2-IN-63		SARS-CoV
	SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal e...		SARS-CoV
T78964	Antileishmanial agent-17		Parasite
	Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells. It specifically interacts with the folate pathway enzymes pteridine redu...		Parasite
T74766	Neuraminidase-IN-12
	NDV-IN-1 is an antiviral agent with high neuraminidase inhibitory activity. NDV-IN-1 exhibits in vitro inhibitory activity against Newcastle disease virus ( NDV ). NDV-IN-1 significantly inhibits NDV infection of Vero ce...
T79661	SARS-CoV-2 3CLpro-IN-18		SARS-CoV
	SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxic...		SARS-CoV
T37537	Carbazomycin D
	Carbazomycin D is a bacterial metabolite that has been found inStreptomycesand has diverse biological activities.1,2It is active against the fungiT. asteroidesandT. mentagrophytes(MIC = 100 μg/ml for both) and the bacter...
T61783	Antimicrobial agent-1
	Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 μg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria....
T71761	Carbazomycin B
	Carbazomycin B is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It is active against a panel of seven fungi and a panel of seven bacteria, as well as P. falciparum a...
T79455	SARS-CoV-2 Mpro-IN-9		SARS-CoV
	SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharma...		SARS-CoV
T60877	Mtb ATP synthase-IN-1
	Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability....
T37173	MPro Inhibitor 11a
	MProinhibitor 11a is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.053 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-i...
T37174	SARS-CoV MPro-IN-1
	MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-in...
T38011	C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
	C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin bindin...
T83881	4-(3,4-Difluorobenzo)curcumin	CDF
	4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigot...
T38297	Ribavirin-13C5	Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a...

Compounds

Synonym: BAY2353,Niclocide

Target: Antibiotic, STAT, Parasite

Amantadine hydrochloride

T1406

Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Everolimus

T1784

Synonym: RAD001,SDZ-RAD

Target: Apoptosis, Others, mTOR, Autophagy

Verofylline

T35048

Synonym: CK 0383,Verofilina,CK-0383,Verofyllinum,CK0383

Synonym: Lignolia,Vetivenol

Target:

Priverosaponin B 22-acetate

T125858

Synonym:

Target:

Acetovanillone primeveroside

T125411

Synonym:

Target:

Benzyl b-primeveroside

4-(2-Nitroethyl)phenyl primeveroside

T130388

Synonym:

Target:

Verosudil hydrochloride

T70735

Synonym:

Target:

Mandelonitrile primeveroside

Synonym: Beta-d-N4-hydroxycytidine

Target: Virus Protease, HCV Protease, SARS-CoV, Topoisomerase

3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide

T8501

Synonym:

Target: Influenza Virus

Bz-RS-ISer(3-Ph)-Ome

T7055

Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

Target: Others, HIV Protease

Carmofur

T1307

Synonym: HCFU

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

SARS-CoV-2 3CLpro-IN-14

T79462

Synonym:

Target: SARS-CoV

Antitubercular agent-29

Antibacterial agent 96

Target: Influenza Virus

Antimycobacterial agent-1

Synonym: BAY2353 sodium

Antileishmanial agent-16

Antileishmanial agent-17

SARS-CoV-2 3CLpro-IN-18

Antimicrobial agent-1

Mtb ATP synthase-IN-1

C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)

T38011

Synonym:

Target:

4-(3,4-Difluorobenzo)curcumin

Synonym: Ribavirin-13C5

Target:

Cat No.	Product Name	Synonyms	Targets
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
T83375	2-Phenethyl β-primeveroside
	2-Phenethyl β-primeveroside, a phenolic glycoside, can be isolated from Callianthemum taipaicum [1].
T74198	Beauverolide Ja
	Beauverolide Ja, a cyclotetradepsipeptide and secondary metabolite of Isaria fumosorosea [1], functions as a potent inhibitor of calmodulin (CaM), exhibiting a dissociation constant (Kd) of 0.078 μM and an inhibition con...
T74199	Beauverolide Ka
	Beauverolide Ka, a cyclotetradepsipeptide derived from the Beauveria bassiana fungus, enhances glucose absorption in rat L6 myoblasts cultured at a concentration of 50 μM and exhibits protective effects on HEI-OC1 cells ...
TN5826	Primeverose
	Primeverose is a natural product for research related to life sciences. The catalog number is TN5826 and the CAS number is 26531-85-1.
T79960	Aloveroside A
	Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstrating approximately 18.68% inhibition at a concentration of 100 μg/mL [...
T37008	Reveromycin A
	Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...
T83284	5-O-Primeverosylapigenin
	5-O-Primeverosylapigenin, a member of the primeverosylapigenin class, can be isolated from species within the Gentianaceae family [1].
TN1886	Lucidin primeveroside	Lucidin 3-O-primeveroside	Topoisomerase
	Lucidin primeveroside (Lucidin 3-O-primeveroside) is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent and a food pigment. Lucidin primeveroside can be metabolical...		Topoisomerase
T83239	7-O-Primverosylpseudobaptigenin
	7-O-Primverosylpseudobaptigenin, a natural product, can be isolated from the alcoholic extract of Amur maackia roots [1].
T36585	Isodeoxycholic Acid	isoDCA	Chloride channel , Antibacterial
	Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less...		Chloride channel , Antibacterial
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
T2S1865	Octyl gallate	Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8	Antioxidant , Influenza Virus , Reactive Oxygen Species , Antibacterial , Antifungal , HSV
	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, ...
T40988	(+)-Norlirioferine
	(+)-Norlirioferine is an alkaloid compound that exhibits cell growth inhibitory effects on macrophages and VERO cells.
TN6427	Salviolone
	Salviolone exhibits cytotoxic activity against Vero cells.
T75633	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid
	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) serves as an antitubercular agent, displaying a minimum inhibitory concentration (MIC) of 12.5 μg/mL against Mycobacterium tuberculosis H37Ra. A...
T69368	GKK1032B
	GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. su...
T75490	27-O-(tert-Butyldimethylsilyl)withaferin A
	27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide known for inducing apoptosis, exhibits antiproliferative effects on HeLa, A-549, and MCF-7 human cancer cell lines, as well as on normal Ver...
T82859	Blepharotriol
	Blepharotriol, a phenolic triterpene isolated from Maytenus blepharodes, exhibits antimicrobial activity, with a minimum inhibitory concentration (MIC) of 8-4 µg/ml against Bacillus subtilis. It also demonstrates cytotox...
T35483	19,20-Epoxycytochalasin D
	19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for...
T83693	Magainin 2 TFA	MG2
	Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne...

Natural Products

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Target: Others

2-Phenethyl β-primeveroside

5-O-Primeverosylapigenin

T83284

Synonym:

Target:

Lucidin primeveroside

TN1886

Synonym: Lucidin 3-O-primeveroside

Target: Topoisomerase

7-O-Primverosylpseudobaptigenin

Target: Chloride channel, Antibacterial

Corilagin

T3795

Synonym:

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Octyl gallate

T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid

27-O-(tert-Butyldimethylsilyl)withaferin A

19,20-Epoxycytochalasin D

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02380	RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)	Kluyveromyces marxianus	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precurs...
TMPK-01298	BST2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res...

RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)

TMPH-02380

Species: Kluyveromyces marxianus

Expression System: E. coli

BST2 Protein, Cynomolgus, Recombinant (His)

TMPK-01298

Species: Cynomolgus

Expression System: HEK293