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Search Results for " survival motor neuron protein "

Targets

3

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16757 Risdiplam RO7034067,RG7916 DNA/RNA Synthesis
Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1].
T34664 SMN2-Stablizer-27 SMN2-Stablizer 27,SMN2 Stablizer-27
SMN2-Stablizer-27 is a stablizer of survival of motor neuron 2 (SMN2), and a post-translationally stablizing SMN protein for the treatment of spinal muscular atrophy (SMA).
T38656 Nusinersen
Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03451 SPF30 Protein, Human, Recombinant (His) Human E. coli
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been iden...
TMPH-02228 TRA2B Protein, Human, Recombinant (His & Myc) Human Baculovirus
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-02229 TRA2B Protein, Human, Recombinant (His & SUMO) Human E. coli
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TargetMol