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Cat No. | Product Name | Synonyms | Targets |
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T16757 | Risdiplam | RO7034067,RG7916 | DNA/RNA Synthesis |
Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1]. | |||
T34664 | SMN2-Stablizer-27 | SMN2-Stablizer 27,SMN2 Stablizer-27 | |
SMN2-Stablizer-27 is a stablizer of survival of motor neuron 2 (SMN2), and a post-translationally stablizing SMN protein for the treatment of spinal muscular atrophy (SMA). | |||
T38656 | Nusinersen | ||
Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein. |
Cat No. | Product Name | Species | Expression System |
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TMPY-03451 | SPF30 Protein, Human, Recombinant (His) | Human | E. coli |
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been iden... | |||
TMPH-02228 | TRA2B Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne... | |||
TMPH-02229 | TRA2B Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne... |