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Search Results for " shiga toxin "

7

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T26579 AHU1
AHU1 is a blocker of Shiga Toxin expression in Escherichia coli O157:H7.
T81401 Pritoxaximab
Pritoxaximab is an IgG1κ monoclonal antibody that selectively targets Shiga toxin type 1 [Stx1].
T81174 Setoxaximab
Setoxaximab is a chimeric humanized antibody of the IgG1-κ isotype that specifically targets Shiga toxin type 1 (Stx1).
T80888 Urtoxazumab HuVTm1.1,TMA-15
Urtoxazumab (TMA-15) is a humanized monoclonal antibody targeting Shiga toxin 2 (Stx2) [1].
T61265 Exo2
Exo2 is a secretion inhibitor that hinders the trafficking of Shiga toxin from endosomes to the trans-Golgi network. It inhibits the exit of secretory cargo from the endoplasmic reticulum (ER) and disrupts the Golgi appa...
T36859 C16 Globotriaosylceramide (d18:1/16:0) C16 Globotriaosylceramide (d18:1/16:0)
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj...
T37439 C18 Globotriaosylceramide (d18:1/18:0)
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetat...
Cat No. Product Name Synonyms Targets
T37291 Lyso-Globotriaosylceramide (d18:1) Lyso-Globotriaosylceramide (d18:1)
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02447 Shiga toxin II subunit B Protein, E. coli, Recombinant (His) E. coli E. coli
E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic grou...
TMPY-01659 SDPR Protein, Mouse, Recombinant (aa 2-180, His) Mouse E. coli
Serum deprivation-response protein, also known as Phosphatidylserine-binding protein, Cavin-2 and SDPR, is a member of the PTRF / SDPR family. SDPR is highly expressed in heart and lung, and expressed at lower levels in ...
TargetMol