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Metabolism Serine/threonin kinase

Serine/threonin kinase

A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains). At least 125 of the 500+ human protein kinases are serine/threonine kinases (STK).Serine/Threonine Kinase receptors play a role in the regulation of cell proliferation, programmed cell death (apoptosis), cell differentiation, and embryonic development.
Cat No. product name
T0610 Piceatannol Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activ...
T1606 Fasudil Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T1808 kb-NB77-78 kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
T1863 CID2011756 CID-2011756 is an ATP-competitive and specific PKD1 inhibitor.
T2062 kb NB 142-70 kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).
T2458 CID755673 CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, ...
T3050 ML-7 hydrochloride ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-mus...
T3060 Fasudil hydrochloride Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T4291 (+)-Isocorydine hydrochloride (+)-Isocorydine is a eukaryote protein kinases Inhibitor.
T5194 SPHINX31 SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
TQ0104 CRT0066101 dihydrochloride CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).
T2153 1 nM-PP1 1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T16931 SRPKIN-1 SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
T1954 SRPIN340 SRPIN340, a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
T7444 6-(Dimethylamino)purine 6-(Dimethylamino)purine is a serine threonine protein kinase and CDK  inhibitor
T1858 CID 797718 CID797718 is a protein kinase D1 (PKD1) inhibitor.
T8957 CRT0066101 CRT0066101 is an inhibitor of PKD.
TP1890L1 MLCK inhibitor peptide 18 acetate(224579-74-2 free base) MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kina...
T8957L CRT0066101 dihydrochloride(956121-30-5 free base) CRT0066101 dihydrochloride is an inhibitor of PKD.
Piceatannol
T0610CAS 10083-24-6
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activ...
Fasudil
T1606CAS 103745-39-7
Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
kb-NB77-78
T1808CAS 1350622-33-1
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
CID2011756
T1863CAS 638156-11-3
CID-2011756 is an ATP-competitive and specific PKD1 inhibitor.
kb NB 142-70
T2062CAS 1233533-04-4
kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).
CID755673
T2458CAS 521937-07-5
CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, ...
ML-7 hydrochloride
T3050CAS 110448-33-4
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-mus...
Fasudil hydrochloride
T3060CAS 105628-07-7
Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
(+)-Isocorydine hydrochloride
T4291CAS 13552-72-2
(+)-Isocorydine is a eukaryote protein kinases Inhibitor.
SPHINX31
T5194CAS 1818389-84-2
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
CRT0066101 dihydrochloride
TQ0104CAS 1883545-60-5
CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).
1 nM-PP1
T2153CAS 221244-14-0
1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
SRPKIN-1
T16931CAS 2089226-94-6
SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
SRPIN340
T1954CAS 218156-96-8
SRPIN340, a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
6-(Dimethylamino)purine
T7444CAS 938-55-6
6-(Dimethylamino)purine is a serine threonine protein kinase and CDK  inhibitor
CID 797718
T1858CAS 370586-05-3
CID797718 is a protein kinase D1 (PKD1) inhibitor.
CRT0066101
T8957CAS 956121-30-5
CRT0066101 is an inhibitor of PKD.
MLCK inhibitor peptide 18 acetate(224579-74-2 free base)
TP1890L1CAS TP1890L1
MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kina...
CRT0066101 dihydrochloride(956121-30-5 free base)
T8957LCAS 2308510-39-4
CRT0066101 dihydrochloride is an inhibitor of PKD.