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Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
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Search Result

Search Results for " serine-protease "

Targets

Proteasome

71

Compounds

10

Natural Products

211

Recombinant Proteins

1

Reagents

Cat No. Product Name Synonyms Targets
T8350 TPCK Proteasome
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
T13408 ZK824190 Others , Serine Protease
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).
TP1277 Bradykinin Endogenous Metabolite , Bradykinin Receptor
Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol...
T11666 IPR-803 Serine/threonin kinase
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.
T11885 LSP-249 Others
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.
T4058 R-IMPP Others , Serine/threonin kinase
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
T10547 BioE-1115 Serine/threonin kinase , Casein Kinase
BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
T13257 Upamostat PAI-1 , Serine/threonin kinase , Serine Protease
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
T7017 WNK463 Serine/threonin kinase
WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
T8936 Proteinase K proteinase K for tritirachium album,Protease K Others
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...
T4524 SBC-110736 SBC110736 Others , Serine/threonin kinase
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor
T9920 Evolocumab Others
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
T14358 Avoralstat BCX4161 Others
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
T9276 SBC-115337 Others , Serine/threonin kinase
SBC-115337 is a PCSK9 inhibitor.
T8645 PF-06446846 Others
PF 06446846 is a potent and selective PCSK9 inhibitor
T2626 SBC-115076 SBC115076 Others , Serine/threonin kinase
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T5456 WNK-IN-11 Allosteric WNK Kinase Inhibitor Serine/threonin kinase
WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)
T6370 AEBSF hydrochloride AEBSF HCl,Pefabloc SC Thrombin , Serine Protease , Influenza Virus
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.
T8676 FOY 251 Others , Serine/threonin kinase , SARS-CoV
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T8362 Benzamidine hydrochloride Benzamidine HCl Serine/threonin kinase , Serine Protease
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
T1954 SRPIN340 SRPK inhibitor Virus Protease , Serine/threonin kinase
SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
T31206 Darexaban YM 150,Darexaban, Tanexaban,YM150 Factor Xa
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...
T3359 Aprotinin Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin Others , Serine Protease , Influenza Virus , Proteasome
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...
T2392 Nafamostat mesylate FUT-175 Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
T19763 Cetraxate hydrochloride DV-1006,DV 1006,Cetraxate HCl,DV1006 Serine/threonin kinase
Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.
T2391 Camostat mesylate FOY-S980,FOY305,Camostat mesilate Serine/threonin kinase , SARS-CoV , Sodium Channel
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T6190 Telaprevir VX-950,LY-570310,Incivek,MP-424 HCV Protease , SARS-CoV
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
T0372 Gabexate mesylate FOY Factor Xa , Serine Protease , Proteasome
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh...
T9268 Ulinastatin Others
Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
T73594 Chymotrypsin Chymotrypsin A Serine/threonin kinase
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas that cleaves protein chains on the carboxyl side of aromatic amino acids.
T78409L Boc-Val-Pro-Arg-MCA TFA
Boc-Val-Pro-Arg-MCA TFA is a sensitive fluorescent substrate that is a thrombin substrate for the determination of trypsin-like serine protease activity.
T40495 Elastase from porcine pancreas EC 3.2.1.35 Others
Porcine pancreatic elastase is a serine protease composed of a single polypeptide chain with 240 amino acid residues. It has the ability to hydrolyze polypeptides and proteins, and can induce emphysema in hamsters.
T4317 PF 429242 NPC1L1 , Lipid
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat...
T13568L BCX 1470 hydrochloride BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl Serine Protease , Complement System
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.
TP1792L KKI-5 acetate(97145-43-2 free base) Serine Protease
KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T60085 MM3122 GTPL11533,MM-3122,Ac-GQFR-kbt SARS-CoV
MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.
T76870 Narsoplimab OMS 721 SARS-CoV
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac...
T3226 Paritaprevir ABT-450,Veruprevir HCV Protease
Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...
T22619 Butabindide oxalate Others
CCK-inactivating serine protease (tripeptidyl peptidase II) inhibitor
T23052 Nafamostat Others
Nafamostat is a synthetic serine protease inhibitor and is an anticoagulant.
T23051 Nafamostat hydrochloride Others
Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.
T70110 CVS-1578
CVS-1578 is a potent serine protease inhibitor, targeting the S2S3 thrombin and FXa subsites.
T10082 DPP-IV-IN-1 Others
DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).
T76157 Chymotrypsinogen
Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .
T28241 Ono 3403 Ono3403,Ono-3403
Ono 3403 is a synthetic serine protease inhibitor. Ono 3403 inhibits lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production. ONO-3403 also has an antitumor effect on malignant tumors.
TP1628 Activated Protein C (390-404), human
Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1].
T19580 Thrombin (MW 37kDa) Thrombin Thrombin
Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.
T6564L Leupeptin Leupeptin Ac-LL,NK-381
Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), ...
TP2234 Coagulation factor II (thrombin) B chain fragment [Homo sapiens] Others
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser...
T74576 Manusiran
Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer [1] .

Compounds

TPCK
T8350
Synonym:
Target: Proteasome
ZK824190
T13408
Synonym:
Target: Others, Serine Protease
Bradykinin
TP1277
Synonym:
Target: Endogenous Metabolite, Bradykinin Receptor
IPR-803
T11666
Synonym:
Target: Serine/threonin kinase
LSP-249
T11885
Synonym:
Target: Others
R-IMPP
T4058
Synonym:
Target: Others, Serine/threonin kinase
BioE-1115
T10547
Synonym:
Target: Serine/threonin kinase, Casein Kinase
Upamostat
T13257
Synonym:
Target: PAI-1, Serine/threonin kinase, Serine Protease
WNK463
T7017
Synonym:
Target: Serine/threonin kinase
Proteinase K
T8936
Synonym: proteinase K for tritirachium album,Protease K
Target: Others
SBC-110736
T4524
Synonym: SBC110736
Target: Others, Serine/threonin kinase
Evolocumab
T9920
Synonym:
Target: Others
Avoralstat
T14358
Synonym: BCX4161
Target: Others
SBC-115337
T9276
Synonym:
Target: Others, Serine/threonin kinase
PF-06446846
T8645
Synonym:
Target: Others
SBC-115076
T2626
Synonym: SBC115076
Target: Others, Serine/threonin kinase
WNK-IN-11
T5456
Synonym: Allosteric WNK Kinase Inhibitor
Target: Serine/threonin kinase
AEBSF hydrochloride
T6370
Synonym: AEBSF HCl,Pefabloc SC
Target: Thrombin, Serine Protease, Influenza Virus
FOY 251
T8676
Synonym:
Target: Others, Serine/threonin kinase, SARS-CoV
Benzamidine hydrochloride
T8362
Synonym: Benzamidine HCl
Target: Serine/threonin kinase, Serine Protease
SRPIN340
T1954
Synonym: SRPK inhibitor
Target: Virus Protease, Serine/threonin kinase
Darexaban
T31206
Synonym: YM 150,Darexaban, Tanexaban,YM150
Target: Factor Xa
Aprotinin
T3359
Synonym: Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin
Target: Others, Serine Protease, Influenza Virus, Proteasome
Nafamostat mesylate
T2392
Synonym: FUT-175
Target: Apoptosis, Serine/threonin kinase, SARS-CoV, Serine Protease
Cetraxate hydrochloride
T19763
Synonym: DV-1006,DV 1006,Cetraxate HCl,DV1006
Target: Serine/threonin kinase
Camostat mesylate
T2391
Synonym: FOY-S980,FOY305,Camostat mesilate
Target: Serine/threonin kinase, SARS-CoV, Sodium Channel
Telaprevir
T6190
Synonym: VX-950,LY-570310,Incivek,MP-424
Target: HCV Protease, SARS-CoV
Gabexate mesylate
T0372
Synonym: FOY
Target: Factor Xa, Serine Protease, Proteasome
Ulinastatin
T9268
Synonym:
Target: Others
Chymotrypsin
T73594
Synonym: Chymotrypsin A
Target: Serine/threonin kinase
Boc-Val-Pro-Arg-MCA TFA
T78409L
Synonym:
Target:
Elastase from porcine pancreas
T40495
Synonym: EC 3.2.1.35
Target: Others
PF 429242
T4317
Synonym:
Target: NPC1L1, Lipid
BCX 1470 hydrochloride
T13568L
Synonym: BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl
Target: Serine Protease, Complement System
KKI-5 acetate(97145-43-2 free base)
TP1792L
Synonym:
Target: Serine Protease
MM3122
T60085
Synonym: GTPL11533,MM-3122,Ac-GQFR-kbt
Target: SARS-CoV
Narsoplimab
T76870
Synonym: OMS 721
Target: SARS-CoV
Paritaprevir
T3226
Synonym: ABT-450,Veruprevir
Target: HCV Protease
Butabindide oxalate
T22619
Synonym:
Target: Others
Nafamostat
T23052
Synonym:
Target: Others
Nafamostat hydrochloride
T23051
Synonym:
Target: Others
CVS-1578
T70110
Synonym:
Target:
DPP-IV-IN-1
T10082
Synonym:
Target: Others
Chymotrypsinogen
T76157
Synonym:
Target:
Ono 3403
T28241
Synonym: Ono3403,Ono-3403
Target:
Activated Protein C (390-404), human
TP1628
Synonym:
Target:
Thrombin (MW 37kDa)
T19580
Synonym: Thrombin
Target: Thrombin
Leupeptin
T6564L
Synonym: Leupeptin Ac-LL,NK-381
Target:
coagulation factor II (thrombin) B chain fragment [Homo sapiens]
TP2234
Synonym:
Target: Others
Manusiran
T74576
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
TN2082 Pinostrobin Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...
T5S0689 Demethylwedelolactone Serine Protease
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.
T2O2730 L-Serine (S)-Serine,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid Endogenous Metabolite
L-Serine (serine) is a non-essential amino acid in humans, L-Serine is present and functionally important in many proteins.L-Serine is also found at the active site of the serine protease enzyme class that includes tryps...
T4915 β-Glycerophosphate disodium salt hydrate Phosphatase , Endogenous Metabolite
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func...
TN6872 Trypsin Protease-activated Receptor
Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...
T75648 Rivulariapeptolides 1155
Rivulariapeptolides 1155 is a potent serine protease inhibitor, exhibiting inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1].
T75649 Rivulariapeptolides 1185
Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1].
T75652 Molassamide B
Molassamide B, a serine protease inhibitor, exhibits potent inhibitory activity, as evidenced by its IC50 values of 24.65 nM against chymotrypsin, 11.69 nM against elastase, and 5.42 nM against proteinase K [1].
T75651 Rivulariapeptolides 988
Rivulariapeptolides 988 demonstrates significant potency and selectivity as a serine protease inhibitor, exhibiting IC50 values of 95.46 nM for chymotrypsin, 15.29 nM for elastase, and 85.50 nM for proteinase K [1].
T75650 Rivulariapeptolides 1121
Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1].

Natural Products

Pinostrobin
TN2082
Synonym:
Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF
Demethylwedelolactone
T5S0689
Synonym:
Target: Serine Protease
L-Serine
T2O2730
Synonym: (S)-Serine,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid
Target: Endogenous Metabolite
β-Glycerophosphate disodium salt hydrate
T4915
Synonym:
Target: Phosphatase, Endogenous Metabolite
Trypsin
TN6872
Synonym:
Target: Protease-activated Receptor
Rivulariapeptolides 1155
T75648
Synonym:
Target:
Rivulariapeptolides 1185
T75649
Synonym:
Target:
Molassamide B
T75652
Synonym:
Target:
Rivulariapeptolides 988
T75651
Synonym:
Target:
Rivulariapeptolides 1121
T75650
Synonym:
Target:

Recombinant Proteins

Species：
Human (101)
Mouse (62)
Rat (15)
Cynomolgus (9)
Staphylococcus aureus (4)
BVDV (2)
Bovine (2)
Canine (2)
Agkistrodon contortrix (1)
Bothrops jararaca (1)
Expression System：
HEK293 (115)
E. coli (44)
Human Cells (28)
Baculovirus-Insect Cells (11)
Yeast (7)
Baculovirus (3)
CHO (1)
P. pastoris (1)
in vitro E. coli expression system (1)
Tag：
His (92)
C-6His (26)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (17)
N-terminal 6xHis-tagged (15)
C-His (11)
Tag Free (7)
hFc (7)
C-His-Avi (5)
N-terminal 6xHis-SUMO-tagged (5)
N-terminal 10xHis-tagged (4)
Cat No. Product Name Species Expression System
TMPY-01897 PRSS3 Protein, Human, Recombinant (His) Human HEK293
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-04997 Prostasin/PRSS8 Protein, Rat, Recombinant (His) Rat HEK293
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu...
TMPY-04928 TMPRSS11B Protein, Human, Recombinant (His) Human HEK293
TMPRSS11B Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 44.3 kDa. Accession number: CAD91168.1
TMPY-00274 Enterokinase Protein, Bovine, Recombinant (His) Bovine Yeast
Enterokinase Protein, Bovine, Recombinant (His) is expressed in Yeast with His tag. The predicted molecular weight is 27.1 kDa. Accession number: P98072-1
TMPY-04985 TMPRSS11D Protein, Human, Recombinant (His) Human HEK293
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ...
TMPH-02643 Enteropeptidase Protein, Mouse, Recombinant (His & Myc) Mouse HEK293
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
TMPJ-01320 BSSP-4 Protein, Human, Recombinant (His) Human Human Cells
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...
TMPH-02553 BSSP-4 Protein, Mouse, Recombinant (His) Mouse E. coli
BSSP-4 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPY-00905 Prostasin/PRSS8 Protein, Human, Recombinant (His) Human HEK293
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu...
TMPJ-01253 Serpin A3N Protein, Mouse, Recombinant (His) Mouse Human Cells
Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, an...
TMPH-02644 Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
TMPJ-01203 HATL5 Protein, Human, Recombinant (His) Human Human Cells
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease tha...
TMPJ-01282 Serpin B12 Protein, Human, Recombinant (His) Human Human Cells
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPY-02117 Marapsin Protein, Human, Recombinant (His) Human HEK293
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasi...
TMPY-01580 PRSS2 Protein, Mouse, Recombinant (His) Mouse HEK293
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists...
TMPJ-00452 Serpin A1a Protein, Mouse, Recombinant (His) Mouse Human Cells
Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elast...
TMPJ-01069 Serpin A1e Protein, Mouse, Recombinant (His) Mouse Human Cells
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His) Human Human Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPJ-00557 Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) Human Human Cells
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di...
TMPY-04626 Enterokinase/EK Protein, Bovine, Recombinant Bovine P. pastoris
Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the ...
TMPY-02783 Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His) Mouse Baculovirus-Insect Cells
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu...
TMPJ-00980 Complement Factor MASP3 Protein, Human, Recombinant (His) Human Human Cells
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro...
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPH-00708 DegP Protein, E. coli, Recombinant (His) E. coli Yeast
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo...
TMPJ-00544 Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His) Human Human Cells
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is...
TMPH-00986 CORIN Protein, Human, Recombinant (His) Human E. coli
CORIN Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00468 KLK10 Protein, Human, Recombinant (His) Human Human Cells
Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di...
TMPH-03244 Anionic trypsin-2 Protein, Rat, Recombinant (His) Rat Yeast
Anionic trypsin-2 Protein, Rat, Recombinant (His) is expressed in Yeast.
TMPJ-00733 SPINK1 Protein, Human, Recombinant (His) Human Human Cells
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise...
TMPH-03243 Anionic trypsin-1 Protein, Rat, Recombinant (His) Rat Yeast
Anionic trypsin-1 Protein, Rat, Recombinant (His) is expressed in Yeast.
TMPJ-01032 SPINK7 Protein, Human, Recombinant (His) Human Human Cells
Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI...
TMPH-01773 ELANE Protein, Human, Recombinant (GST) Human E. coli
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane pro...
TMPH-03242 Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) Rat E. coli
Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00484 Cationic trypsin Protein, Canine, Recombinant (His & SUMO) Canine E. coli
Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00262 Serpin A12 Protein, Human, Recombinant (GST) Human E. coli
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of ...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPK-00782 PLAU/uPA Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-00686 Complement C2 Protein, Human, Recombinant (His) Human HEK293
Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in ext...
TMPY-02731 SPINK4 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine...
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-00672 Azurocidin/CAP37 Protein, Human, Recombinant (His) Human HEK293
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil...
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His) Human HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPY-02530 Tissue Factor Protein, Human, Recombinant (His) Human HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPY-05094 Tissue Factor Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPY-00904 Urokinase/uPA Protein, Human, Recombinant (His) Human HEK293
Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in compl...
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His) Human Human Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-02258 Kallikrein 3/KLK3 Protein, Human, Recombinant (His) Human HEK293
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i...
TMPY-04962 FAP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04922 FAP Protein, Human, Recombinant (His), Biotinylated Human HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-02154 FAP Protein, Human, Recombinant (His) Human HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
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PRSS3 Protein, Human, Recombinant (His)
TMPY-01897
Species: Human
Expression System: HEK293
Prostasin/PRSS8 Protein, Rat, Recombinant (His)
TMPY-04997
Species: Rat
Expression System: HEK293
TMPRSS11B Protein, Human, Recombinant (His)
TMPY-04928
Species: Human
Expression System: HEK293
Enterokinase Protein, Bovine, Recombinant (His)
TMPY-00274
Species: Bovine
Expression System: Yeast
TMPRSS11D Protein, Human, Recombinant (His)
TMPY-04985
Species: Human
Expression System: HEK293
Enteropeptidase Protein, Mouse, Recombinant (His & Myc)
TMPH-02643
Species: Mouse
Expression System: HEK293
BSSP-4 Protein, Human, Recombinant (His)
TMPJ-01320
Species: Human
Expression System: Human Cells
BSSP-4 Protein, Mouse, Recombinant (His)
TMPH-02553
Species: Mouse
Expression System: E. coli
Prostasin/PRSS8 Protein, Human, Recombinant (His)
TMPY-00905
Species: Human
Expression System: HEK293
Serpin A3N Protein, Mouse, Recombinant (His)
TMPJ-01253
Species: Mouse
Expression System: Human Cells
Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)
TMPH-02644
Species: Mouse
Expression System: E. coli
HATL5 Protein, Human, Recombinant (His)
TMPJ-01203
Species: Human
Expression System: Human Cells
Serpin B12 Protein, Human, Recombinant (His)
TMPJ-01282
Species: Human
Expression System: Human Cells
Marapsin Protein, Human, Recombinant (His)
TMPY-02117
Species: Human
Expression System: HEK293
PRSS2 Protein, Mouse, Recombinant (His)
TMPY-01580
Species: Mouse
Expression System: HEK293
Serpin A1a Protein, Mouse, Recombinant (His)
TMPJ-00452
Species: Mouse
Expression System: Human Cells
Serpin A1e Protein, Mouse, Recombinant (His)
TMPJ-01069
Species: Mouse
Expression System: Human Cells
Serpin A5 Protein, Human, Recombinant (His)
TMPJ-00490
Species: Human
Expression System: Human Cells
Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)
TMPJ-00557
Species: Human
Expression System: Human Cells
Enterokinase/EK Protein, Bovine, Recombinant
TMPY-04626
Species: Bovine
Expression System: P. pastoris
Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His)
TMPY-02783
Species: Mouse
Expression System: Baculovirus-Insect Cells
Complement Factor MASP3 Protein, Human, Recombinant (His)
TMPJ-00980
Species: Human
Expression System: Human Cells
Serpin E2 Protein, Mouse, Recombinant (His)
TMPJ-01083
Species: Mouse
Expression System: Human Cells
DegP Protein, E. coli, Recombinant (His)
TMPH-00708
Species: E. coli
Expression System: Yeast
Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)
TMPJ-00544
Species: Human
Expression System: Human Cells
CORIN Protein, Human, Recombinant (His)
TMPH-00986
Species: Human
Expression System: E. coli
KLK10 Protein, Human, Recombinant (His)
TMPJ-00468
Species: Human
Expression System: Human Cells
Anionic trypsin-2 Protein, Rat, Recombinant (His)
TMPH-03244
Species: Rat
Expression System: Yeast
SPINK1 Protein, Human, Recombinant (His)
TMPJ-00733
Species: Human
Expression System: Human Cells
Anionic trypsin-1 Protein, Rat, Recombinant (His)
TMPH-03243
Species: Rat
Expression System: Yeast
SPINK7 Protein, Human, Recombinant (His)
TMPJ-01032
Species: Human
Expression System: Human Cells
ELANE Protein, Human, Recombinant (GST)
TMPH-01773
Species: Human
Expression System: E. coli
Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His)
TMPH-03242
Species: Rat
Expression System: E. coli
Cationic trypsin Protein, Canine, Recombinant (His & SUMO)
TMPH-00484
Species: Canine
Expression System: E. coli
Serpin A12 Protein, Human, Recombinant (GST)
TMPJ-00262
Species: Human
Expression System: E. coli
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
PLAU/uPA Protein, Mouse, Recombinant (His & Avi)
TMPK-00782
Species: Mouse
Expression System: HEK293
Complement C2 Protein, Human, Recombinant (His)
TMPY-00686
Species: Human
Expression System: HEK293
SPINK4 Protein, Mouse, Recombinant (hFc)
TMPY-02731
Species: Mouse
Expression System: HEK293
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
TMPY-01104
Species: Human
Expression System: HEK293
Azurocidin/CAP37 Protein, Human, Recombinant (His)
TMPY-00672
Species: Human
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (His)
TMPY-00915
Species: Human
Expression System: HEK293
Tissue Factor Protein, Human, Recombinant (His)
TMPY-02530
Species: Human
Expression System: HEK293
Tissue Factor Protein, Cynomolgus, Recombinant (His)
TMPY-05094
Species: Cynomolgus
Expression System: HEK293
Urokinase/uPA Protein, Human, Recombinant (His)
TMPY-00904
Species: Human
Expression System: HEK293
TPSAB1 Protein, Human, Recombinant (His)
TMPJ-01204
Species: Human
Expression System: Human Cells
Kallikrein 3/KLK3 Protein, Human, Recombinant (His)
TMPY-02258
Species: Human
Expression System: HEK293
FAP Protein, Cynomolgus, Recombinant (His)
TMPY-04962
Species: Cynomolgus
Expression System: HEK293
FAP Protein, Human, Recombinant (His), Biotinylated
TMPY-04922
Species: Human
Expression System: HEK293
FAP Protein, Human, Recombinant (His)
TMPY-02154
Species: Human
Expression System: HEK293
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Reagents


Protease Inhibitor Cocktail
(EDTA-Free, 100× in DMSO)
Catalog No. C0001
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