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Search Results for " salt-inducible kinase "

Targets

9

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T17271 YKL-05-099 SIK
YKL-05-099 is an inhibitor of the salt-inducible kinase(SIK1 and SIK3 ; IC50s: 10 and 30 nM, respectively). It has a slightly less potent SIK2-inhibitory (IC50:40 nM).
T5576 YKL-06-061 AMPK , SIK
YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.
T9219 WH-4-025 AMPK , SIK
WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.
T5993 ARN-3236 AMPK , SIK
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectively). ARN-3236 Has anti-cancer activity.
T4599 HG-9-91-01 SIK inhibitor 1 SIK
HG-9-91-01 (SIK inhibitor 1) is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3respectively.
T17272 YKL-06-062 SIK
YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor that inhibits SIK1, SIK2 and SIK3 with IC50s of 2.12 nM, 1.40 nM and 2.86 nM.
T0097 MRT67307 MRT67307 HCl IκB/IKK , Autophagy
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...
T75984 AMARA peptide TFA
AMARA peptide (TFA) serves as a substrate for both salt-inducible kinase (SIK) and adenosine monophosphate-activated protein kinase (AMPK).
T23028 MRT67307 HCl (1190378-57-4 free base) MRT67307 HCl Others
MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i...
Cat No. Product Name Synonyms Targets
T12576 Pterosin B Others
Pterosin B is an salt-inducible kinase 3 (Sik3) signaling inhibitor. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis by inhibiting Sik3.
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