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Cat No. | Product Name | Synonyms | Targets |
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T7740 | Protease-Activated Receptor-4 diTFA | Protease-Activated Receptor-4 diTFA(245443-52-1(free base)) | Protease-activated Receptor |
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist | |||
T38836L | Protease-Activated Receptor-1, PAR-1 Agonist acetate | Protease-activated Receptor | |
Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi... | |||
T7513 | Protease-Activated Receptor-2, amide | SLIGKV-NH2 | Protease-activated Receptor |
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M) | |||
T38836 | Protease-Activated Receptor-1, PAR-1 Agonist | ||
Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio... | |||
T36288 | Protease-Activated Receptor-1, PAR-1 Agonist TFA | ||
Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac... | |||
T7380 | Protease-Activated Receptor-4 | Protease-activated Receptor | |
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy | |||
T36289 | Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA | ||
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1]. | |||
TP1046 | SLIGRL-NH2 | Protease-Activated Receptor-2 Activating Peptide | Protease-activated Receptor |
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. | |||
T36286 | Protease-Activated Receptor-3 (PAR-3) (1-6), human | ||
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells. | |||
T1986L | Atopaxar Hydrobromide | Protease-activated Receptor | |
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T1986 | Atopaxar | E5555,ER-172594-00 | Protease-activated Receptor |
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T64285 | Protease-Activated Receptor-1 antagonist 2 | ||
Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ... | |||
T1893 | Parmodulin 2 | ML 161 | Protease-activated Receptor |
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... | |||
TQ0012 | AZ3451 | Protease-activated Receptor | |
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). | |||
T7137 | I-191 | Protease-activated Receptor | |
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. | |||
T62507 | Protease-Activated Receptor-1 antagonist 1 | ||
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc... | |||
T63382 | Protease-Activated Receptor-1 antagonist 3 | ||
Protease-Activated Receptor-1 antagonist 3 is a potent antagonist (IC50: 7 nM) of Protease-Activated Receptor 1protease-activated receptor-1. antagonist 3 exhibits binding affinity to hERG K+ channels (IC50: 9 μM). | |||
T74266 | Protease-Activated Receptor-1 antagonist 2 | ||
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character... | |||
TP1046L | PAR-2 Activating Peptide acetate | SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate | Protease-activated Receptor |
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2). | |||
T2370 | AC-55541 | AOB2796 | Proteasome , Protease-activated Receptor |
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. | |||
T7625 | TRAP-6 | PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) | Protease-activated Receptor |
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1). | |||
T7013 | Vorapaxar | SCH 530348,MK-5348 | Protease-activated Receptor |
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). | |||
T75902 | SLIGRL-NH2 TFA | Protease-Activated Receptor-2 Activating Peptide TFA | |
SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1]. | |||
T12870 | SCH79797 dihydrochloride | Apoptosis , Others , Protease-activated Receptor | |
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects. | |||
T8917 | PAR-2-IN-1 | IUN76750 | Protease-activated Receptor |
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. | |||
T3098 | Vorapaxar sulfate | SCH 530348 sulfate,Zontivity,vorapaxar monosulfate | Protease-activated Receptor |
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. | |||
TP1065 | PAR-4 Agonist Peptide, amide TFA | PAR-4-AP (TFA),AY-NH2 (TFA) | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b... | |||
T7623 | PAR-4 Agonist Peptide, amide | AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4). | |||
T4186 | AC-264613 | AC264613 | Protease-activated Receptor |
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha... | |||
T7573 | TFLLR-NH2 | TFLLR-NH2(2TFA) | Protease-activated Receptor |
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM). | |||
T7496 | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | Thrombin Receptor Activator for Peptide | Protease-activated Receptor |
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research. | |||
T63966 | BMS-986141 | UDM-003183 | Protease-activated Receptor |
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibits significant antithrombotic effects. | |||
TP1378 | 2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) | 2-Furoyl-LIGRLO-amide | Protease-activated Receptor |
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist. | |||
T21699L | VKGILS-NH2 Acetate | VKGILS-NH2 Acetate (942413-05-0 Free base) | Protease-activated Receptor |
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. | |||
TP1904L | FSLLRY-NH2 TFA(245329-02-6 free base) | Protease-activated Receptor | |
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in iso... | |||
T22792 | FR-171113 | Others | |
Protease-activated receptor 1 antagonist | |||
T23282 | RWJ-56110 | Others | |
protease-activated receptor-1 (PAR1) antagonist | |||
T27406 | GB83 | GB-83,GB 83 | |
GB83 is a selective human protease activated receptor 2 (PAR2) antagonist. | |||
T75871 | FSLLRY-NH2 TFA | ||
FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor [1] . | |||
T11369 | GB-110 | Others | |
GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. | |||
T17200 | UDM-001651 | Others | |
UDM-001651 is an effective and orally bioavailable protease-activated receptor 4 antagonists (IC50=4 nM; Kd=1.4 nM). UDM-001651 displays antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggr... | |||
T80111 | TRAP-5 amide | ||
TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1]. | |||
T22933 | LRGILS-NH2 | Others | |
LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo. | |||
T14684 | BMS-986120 | Others | |
BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist. With IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatele... | |||
T73854 | GB-110 hydrochloride | ||
GB-110 hydrochloride, a potent and orally active nonpeptidic agonist of the protease-activated receptor 2 (PAR2), selectively triggers PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM [1]. | |||
T11369L | GB-110 hydrochloride (1252806-70-4 free base) | GB-110 hydrochloride | Others |
GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR... | |||
TP1965 | Parstatin(human) | Parstatin (human) | |
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation... | |||
TP1966 | Parstatin(mouse) | Parstatin (mouse) | |
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activatio... | |||
T75903 | VKGILS-NH2 TFA | ||
VKGILS-NH2 TFA is a reversed-sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. It demonstrates no impact on cellular DNA synthesis [1] [2]. | |||
T75904 | PAR 4 (1-6) (TFA) | ||
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4. This fragment of PAR 4 [1] exhibits targeted activation properties. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02530 | Tissue Factor Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-05094 | Tissue Factor Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-03347 | EPCR Protein, Rat, Recombinant (His) | Rat | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-02487 | EPCR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-02715 | EPCR Protein, Human, Recombinant (His) | Human | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-03192 | EPCR Protein, Human, Recombinant (hFc) | Human | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-03832 | EPCR Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-02489 | EPCR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-03594 | EPCR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other a... | |||
TMPY-01325 | Tissue Factor Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02318 | Tissue Factor Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-03209 | Tissue Factor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-05083 | Tissue Factor Protein, Human, Recombinant (aa 1-295, His) | Human | Baculovirus-Insect Cells |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02537 | Tissue Factor Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-06957 | Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02238 | TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02235 | TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) | Human | in vitro E. coli expression system |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPY-02027 | BID Protein, Human, Recombinant | Human | E. coli |
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro... | |||
TMPY-02065 | BID Protein, Mouse, Recombinant (His & GST) | Mouse | E. coli |
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro... | |||
TMPY-01112 | PEDF Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco... | |||
TMPY-01328 | PEDF Protein, Human, Recombinant (His) | Human | HEK293 |
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco... | |||
TMPY-00266 | PEDF Protein, Rat, Recombinant (His) | Rat | HEK293 |
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco... | |||
TMPY-02014 | Coagulation factor VII/F7 Protein, Human, Recombinant (His) | Human | HEK293 |
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is... | |||
TMPY-06195 | IGF1R/CD221 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-06905 | IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-04360 | IGF1R/CD221 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... |