Search Result

Search Results for " platelet-aggregation "

Targets

211

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T5036	Cangrelor tetrasodium		GPR , P2Y Receptor
	Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.		GPR , P2Y Receptor
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T15031	CYM50260		Others , LPL Receptor
	CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.		Others , LPL Receptor
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T15047	Dacisteine	N,S-Diacetyl-L-cysteine	Others
	Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).		Others
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T4190	Ticlopidine	PCR 5332,Ticlid	ATPase , Adiponectin receptor
	Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.		ATPase , Adiponectin receptor
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T16164	MY-5445	N-(3-chlorophenyl)-4-phenylphthalazin-1-amine	PDE
	MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).		PDE
T0230	Prasugrel	LY640315,CS-747,PCR 4099	P2Y Receptor
	Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those...		P2Y Receptor
T2569	Chlorotrianisene	tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
T0182L	Clopidogrel hydrogen sulfate	(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel	P450 , P2Y Receptor
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.		P450 , P2Y Receptor
T6952	Prasugrel Hydrochloride	LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl	P2Y Receptor
	Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.		P2Y Receptor
T15757	Limaprost	17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206	PGE Synthase
	Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood...		PGE Synthase
T3757	NQ301		Thrombin , Platelet aggregation
	NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).		Thrombin , Platelet aggregation
T1618	Dipyridamole	Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine	PDE
	Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.		PDE
T12857	SC-52012		Others
	SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.		Others
T35161	Xemilofiban	SC-54684A,SC54684A,SC 54684A	Others
	Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina.		Others
T8575	ENFENAMIC ACID		Platelet aggregation
	Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic.		Platelet aggregation
T6182	Tirofiban	L700462,Aggrastat,MK383	Integrin
	Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.		Integrin
T13368	YLF-466D	C24	AMPK
	YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.		AMPK
T31213	Dazmegrel	UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR
	Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.		PPAR
T3608	Carbasalate calcium	Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium	Platelet aggregation
	Carbasalate calcium (Rheomin) is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor.		Platelet aggregation
T61345L	Orbofiban TFA	Orbofiban TFA(163250-90-6 Free base)	Integrin
	Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary syndromes.		Integrin
T9887	Ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate		Platelet aggregation
	ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate is a platelet aggregation inhibitor.		Platelet aggregation
T0182	Clopidogrel	(S)-Clopidogrel,SR-25990C	P2Y Receptor
	Clopidogrel (SR-25990C), a P2Y12 receptor antagonist, decreases platelet aggregation.		P2Y Receptor
T15338	Foropafant	SR27417	Others , Platelet aggregation
	Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM). Foropafant potently inhibits the PAF-induced aggregation of rabbit and human platelets.		Others , Platelet aggregation
T0362	Ticlopidine hydrochloride	Ticlodone,Ticlopidine HCl,Ticlodix	Adenosine Receptor
	Ticlopidine hydrochloride (Ticlodix) is an effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.		Adenosine Receptor
T74030	MAHMA NONOate		Endogenous Metabolite , NO Synthase
	MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.		Endogenous Metabolite , NO Synthase
T24542	NP-313	NP 313,NSC 4264,NSC-4264,NSC4264
	NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux.
T25635	Lateritin	Bassiatin	Acyltransferase
	Lateritin (Bassiatin) is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella lateritium. Bassiatin is the (3S,6R) isomer.		Acyltransferase
TP1925L	TcY-NH2 TFA(327177-34-4 free base)		Protease-activated Receptor
	tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.		Protease-activated Receptor
T24567	Octimibate	Octimibato	Prostaglandin Receptor
	Octimibate (Octimibato) is a non-prostaglandin platelet aggregation inhibitor and cyclic prostaglandin agonist.Octimibate is used in the treatment of cardiovascular disease and can be used to study atherosclerosis and th...		Prostaglandin Receptor
T12808	S-Nitroso-N-acetyl-DL-penicillamine	SNAP	NO Synthase
	S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .		NO Synthase
T10502	Benzcyclane	Benzcyclan,Bencyclane	Others , Platelet aggregation
	Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders.		Others , Platelet aggregation
T15577	Indobufen	Ibustrin	COX
	Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue fac...		COX
T29097	VAS 3947	VA-S3947,VA S3947,VAS3947	Apoptosis , NADPH-oxidase
	VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to protein aggregation and misfolding, independent of anti-NOX act...		Apoptosis , NADPH-oxidase
T37428	TRPC6-PAM-C20	TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one	TRP/TRPV Channel
	TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced p...		TRP/TRPV Channel
T15108	DG-041		Prostaglandin Receptor
	DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...		Prostaglandin Receptor
TP1447L1	Arg-Gly-Asp-Cys acetate	Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate	Others
	Arg-Gly-Asp-Cys acetate inhibits platelet aggregation and fibrinogen binding. Arg-Gly-Asp-Cys acetate is the binding motif of fibronectin to cell adhesion molecules.		Others
T1002	Etodolac	Ultradol,AY-24236,Etodolic acid,Lodine	Retinoid Receptor , COX
	Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ...		Retinoid Receptor , COX
T15130	Dilazep dihydrochloride		Others
	Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc...		Others
T4132	BPTU	BMS-646786	P2Y Receptor
	BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced...		P2Y Receptor
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin
T77442	Glenzocimab	ACT017	Others
	Glenzocimab (ACT017) is a Fab fragment of a humanized anti-GPVI monoclonal antibody. Glenzocimab demonstrated inhibition of collagen-induced platelet aggregation in an ischemic stroke model. Glenzocimab has been studied ...		Others
T17039	Terbogrel	BIBV 308SE	Prostaglandin Receptor
	Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a...		Prostaglandin Receptor
T6040	Aloxistatin	E64d,Loxistatin,E64c ethyl ester	SARS-CoV , Cysteine Protease
	Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with...		SARS-CoV , Cysteine Protease

Compounds

cangrelor tetrasodium

T5036

Synonym:

Target: GPR, P2Y Receptor

Target: Syk, Src, p97

Target: Others, LPL Receptor

Ozagrel

T6236

Synonym: OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

Dacisteine

T15047

Synonym: N,S-Diacetyl-L-cysteine

Target: Apoptosis, JAK, STAT

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

Ticlopidine

T4190

Synonym: PCR 5332,Ticlid

Target: ATPase, Adiponectin receptor

Ozagrel hydrochloride

T6625

Synonym: Ozagrel HCl,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

MY-5445

T16164

Synonym: N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

Target: PDE

Prasugrel

T0230

Synonym: LY640315,CS-747,PCR 4099

Target: P2Y Receptor

Chlorotrianisene

T2569

Synonym: tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, COX

Clopidogrel hydrogen sulfate

T0182L

Synonym: (S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel

Target: P450, P2Y Receptor

Prasugrel Hydrochloride

T6952

Synonym: LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl

Target: P2Y Receptor

Limaprost

T15757

Synonym: 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206

Target: Thrombin, Platelet aggregation

Dipyridamole

T1618

Synonym: Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine

Synonym: SC-54684A,SC54684A,SC 54684A

Target: Platelet aggregation

Tirofiban

T6182

Synonym: L700462,Aggrastat,MK383

Synonym: UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485

Target: PPAR

Carbasalate calcium

T3608

Synonym: Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium

Target: Platelet aggregation

Orbofiban TFA

T61345L

Synonym: Orbofiban TFA(163250-90-6 Free base)

Target: Integrin

ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate

T9887

Synonym:

Target: Platelet aggregation

Clopidogrel

T0182

Synonym: (S)-Clopidogrel,SR-25990C

Target: Others, Platelet aggregation

Ticlopidine hydrochloride

T0362

Synonym: Ticlodone,Ticlopidine HCl,Ticlodix

Target: Adenosine Receptor

MAHMA NONOate

T74030

Synonym:

Target: Endogenous Metabolite, NO Synthase

NP-313

T24542

Synonym: NP 313,NSC 4264,NSC-4264,NSC4264

Target: Acyltransferase

tcY-NH2 TFA(327177-34-4 free base)

TP1925L

Synonym:

Target: Protease-activated Receptor

Octimibate

T24567

Synonym: Octimibato

Target: Prostaglandin Receptor

S-Nitroso-N-acetyl-DL-penicillamine

Synonym: Benzcyclan,Bencyclane

Target: Others, Platelet aggregation

Synonym: VA-S3947,VA S3947,VAS3947

Target: Apoptosis, NADPH-oxidase

TRPC6-PAM-C20

T37428

Synonym: TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one

Target: TRP/TRPV Channel

DG-041

T15108

Synonym:

Target: Prostaglandin Receptor

Arg-Gly-Asp-Cys acetate

TP1447L1

Synonym: Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate

Target: Others

Etodolac

T1002

Synonym: Ultradol,AY-24236,Etodolic acid,Lodine

Target: Retinoid Receptor, COX

Dilazep dihydrochloride

Dabigatran Etexilate Mesylate

T5133

Synonym: BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Prostaglandin Receptor

Aloxistatin

T6040

Synonym: E64d,Loxistatin,E64c ethyl ester

Target: SARS-CoV, Cysteine Protease

Cat No.	Product Name	Synonyms	Targets
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T3781	Jujuboside B		Others
	Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.		Others
T3S1591	Notoginsenoside Fc		Others , Autophagy
	1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.		Others , Autophagy
T0853	Adenosine	D-Adenosine,Adenine riboside	Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
	Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
TN4222	Homoeriodictyol 7-O-β-D-glucoside	Homoeriodictyol 7-O-glucoside	Others , Platelet aggregation
	Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF).		Others , Platelet aggregation
TN6924	Anhydrosafflor yellow B	(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB	Others
	Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...		Others
T28551	Ro 09-0680	Ro 09 0680,Ro-09-0680
	Ro 09-0680 is an inhibitor of platelet aggregation.
T3817	Darutigenol		Others
	Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.		Others
TN2343	Pseudojervine	Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine	Platelet aggregation
	Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
T12164	N6-(4-Hydroxybenzyl)adenosine	Para-topolin riboside	P2Y Receptor
	N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) is a platelet aggregation inhibitor.		P2Y Receptor
TQ0036	Anemarrhenasaponin I		Others
	Anemarrhenasaponin I shows the remarkable inhibiting effect on platelet aggregation.		Others
TN1057	Veratrosine	Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation
	Veratrosine (Veratramine-beta-D-glucoside) is an alkaloid isolated from the herbs of Veratrum nigrum. Veratrosine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
TN1643	Ferulamide	4-Hydroxy-3-methoxycinnamide	PAFR , AChR
	Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.		PAFR , AChR
T11012	Dextran	Dextran 40	Platelet aggregation
	Dextran has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume.		Platelet aggregation
T1723	Adenosine 5'-diphosphate	Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite
	Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.		Endogenous Metabolite
T2898	Andrographolide	Andrographis	SARS-CoV , Influenza Virus , NF-κB , Autophagy
	Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.		SARS-CoV , Influenza Virus , NF-κB , Autophagy
TN6710	Methyl acetylsalicylate	ACETYLSALICYLIC ACID METHYL ESTER	Others
	Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation		Others
T3734	3',4'-Dihydroxyacetophenone	Qingxintong,4-Acetylpyrocatechol	Tyrosinase , Platelet aggregation
	3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.		Tyrosinase , Platelet aggregation
T3429	Protopine	Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species , Platelet aggregation , Histamine Receptor
	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
TN2315	Xanthopurpurin		Platelet aggregation , Antifection
	Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-ind...		Platelet aggregation , Antifection
T3408	Syringin	Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine	NOS , Autophagy
	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.		NOS , Autophagy
T4S1658	Benzoyloxypaeoniflorin	Benzoyloxypeoniflorin	NF-κB , Tyrosinase
	Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.		NF-κB , Tyrosinase
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
T2S1749	Protogracillin		Others
	Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.		Others
TN1873	Lirinidine		Others
	(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...		Others
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
TN1254	3'-Methoxydaidzein		Sodium Channel
	3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla...		Sodium Channel
TN1170	1-Cinnamoylpyrrolidine		Platelet aggregation
	1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolid...		Platelet aggregation
TN6975	Cirsiumaldehyde	5,5’-oxydimethylenebis(2-furfural)	Platelet aggregation
	Cirsiumaldehyde is a compound isolated from the mature fruits of Lobelia chinensis, Cornus officinalis, and the fruits of Hippophae rhamnoides.Cirsiumaldehyde in the presence of collagen inhibited U46619-induced (1~5 uM)...		Platelet aggregation
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
TN1622	Ermanin		NOS , Influenza Virus , COX , HIV Protease , Antibacterial , Antibiotic
	Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.Ermanin has anti-inflammatory activity by inhibiting the exp...
T3427	Polydatin	Piceid,Polydotin Peceid	Apoptosis , Mitophagy , NF-κB , Autophagy
	Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In th...		Apoptosis , Mitophagy , NF-κB , Autophagy
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T7052	Gnetol		Tyrosinase , COX , HDAC , AChR
	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...		Tyrosinase , COX , HDAC , AChR
TN5045	Spiradine F		PAFR
	Spiradine F can significantly inhibit platelet-activating factor(PAF)-induced platelet aggregation in a concentration-dependent manner.		PAFR
TN3443	Aristolactam AII		PAFR
	Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity.		PAFR
TN4181	Hancinone C		PAFR
	Hancinone C shows inhibitory activity against the platelet aggregation caused by PAF.		PAFR
TN3964	Epiaschantin		Others
	(+)-Epiaschantin shows marginal cancer cell line inhibitory activities. It also has anti-platelet aggregation activity.		Others
TN6536	Decuroside I
	Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet.
TN1310	6-Hydroxykaempferol 3,6-diglucoside		Others
	6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- ind...		Others
TN1388	Angelol K		Others
	Angelol K shows significant activity on human platelet aggregation.		Others
TN1309	6-Hydroxykaempferol-3,6,7-triglucoside		Others
	6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- ind...		Others
TN1980	Neocryptotanshinone		Others
	Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid.		Others
TN6472	Columbianetin beta-D-glucopyranoside
	Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties, it also shows strong inhibiting activity against platelet aggregation.
TN1095	Ginsenoside Rk2		VEGFR
	Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.		VEGFR
------------------------ More ------------------------

Natural Products

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Target: Others, Autophagy

Adenosine

T0853

Synonym: D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

Sulfuretin

TN2244

Synonym:

Target: NF-κB, Autophagy

Prostaglandin E1

T1626

Synonym: PGE1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Homoeriodictyol 7-O-β-D-glucoside

TN4222

Synonym: Homoeriodictyol 7-O-glucoside

Target: Others, Platelet aggregation

Anhydrosafflor yellow B

TN6924

Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB

Target: Others

Ro 09-0680

T28551

Synonym: Ro 09 0680,Ro-09-0680

Synonym: Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine

Target: Platelet aggregation

N6-(4-Hydroxybenzyl)adenosine

T12164

Synonym: Para-topolin riboside

Synonym: Veratramine 3-glycoside,Veratramine-beta-D-glucoside

Target: Platelet aggregation

Ferulamide

TN1643

Synonym: 4-Hydroxy-3-methoxycinnamide

Target: Platelet aggregation

Adenosine 5'-diphosphate

T1723

Synonym: Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Andrographolide

T2898

Synonym: Andrographis

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Methyl acetylsalicylate

TN6710

Synonym: ACETYLSALICYLIC ACID METHYL ESTER

Target: Others

3',4'-Dihydroxyacetophenone

T3734

Synonym: Qingxintong,4-Acetylpyrocatechol

Target: Tyrosinase, Platelet aggregation

Protopine

T3429

Synonym: Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor

Xanthopurpurin

TN2315

Synonym:

Target: Platelet aggregation, Antifection

Syringin

T3408

Synonym: Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine

Target: NOS, Autophagy

Benzoyloxypaeoniflorin

T4S1658

Synonym: Benzoyloxypeoniflorin

Target: NF-κB, Tyrosinase

Cepharanthine

T0131

Synonym: NSC-623442

Target: Apoptosis, TNF, HIV Protease, Autophagy

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

dencichine

TL0001

Synonym: L-Dencichin,ODAP,Dencichin

Target: Others, HIF/HIF Prolyl-Hydroxylase

3'-Methoxydaidzein

TN1254

Synonym:

Target: Sodium Channel

1-Cinnamoylpyrrolidine

TN1170

Synonym:

Target: Platelet aggregation

Cirsiumaldehyde

TN6975

Synonym: 5,5’-oxydimethylenebis(2-furfural)

Target: Platelet aggregation

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Ermanin

TN1622

Synonym:

Target: NOS, Influenza Virus, COX, HIV Protease, Antibacterial, Antibiotic

Polydatin

T3427

Synonym: Piceid,Polydotin Peceid

Target: Apoptosis, Mitophagy, NF-κB, Autophagy

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Gnetol

T7052

Synonym:

Target: Tyrosinase, COX, HDAC, AChR

6-Hydroxykaempferol 3,6-diglucoside

6-Hydroxykaempferol-3,6,7-triglucoside

Columbianetin beta-D-glucopyranoside

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation r...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPY-00939	Thrombopoietin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc)	Human	HEK293
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-02808	CD39 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-05151	CD39 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	Baculovirus-Insect Cells
	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-01126	CD39 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-02778	ENPP2 Protein, Human, Recombinant (His)	Human	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-00463	ENPP2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-00882	Mer Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04330	Mer Protein, Human, Recombinant	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-02521	HIST3H2A Protein, Human, Recombinant	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident ...
TMPH-00322	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	Yeast
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00321	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00323	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00320	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	Yeast
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-01822	P2Y1 Protein, Human, Recombinant (His)	Human	E. coli
	Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately p...
TMPH-00216	SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)	Bothrops jararaca	E. coli
	Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation.
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPH-03283	CD39 Protein, Rat, Recombinant (His)	Rat	Baculovirus
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPH-00215	SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)	Bothrops jararaca	E. coli
	Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet aggregation through its interaction with GPIb (GP1BA/GP1BB), and ac...
TMPH-03121	CXCL4 Protein, Pig, Recombinant (His & Myc)	Sus scrofa (Pig)	E. coli
	Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophil...
TMPH-00217	SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)	Bothrops leucurus	E. coli
	Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also obser...
TMPH-02571	CD9 Protein, Mouse, Recombinant (His)	Mouse	in vitro E. coli expression system
	Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays...
TMPJ-01124	PDIA6 Protein, Human, Recombinant (His)	Human	Human Cells
	Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPY-04201	Thrombopoietin Protein, Human, Recombinant (hFc)	Human	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-01609	Thrombopoietin Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPH-03163	SVTLE Protein, Protobothrops flavoviridis, Recombinant (His & Myc)	Protobothrops flavoviridis	E. coli
	Thrombin-like snake venom serine protease that clots fibrinogen (FGA) by releasing fibrinopeptide A. According to PubMed:8585090, only cleaves rabbit fibrinogen, whereas no specificity is described in PubMed:3910643 (tes...
TMPH-00214	SVMP Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Snake venom zinc metalloproteinase that acts on fibrinogen, fibrin, fibronectin (FN1), type I collagen, type IV collagen, integrin alpha-7/beta-1 (ITGA7/ITGB1) and integrin alpha-1/beta-1 (ITGA1/ITGB1). Binds to fibronec...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPY-03161	JAM-A Protein, Rat, Recombinant (His)	Rat	HEK293
	Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as...
TMPY-01035	JAM-A Protein, Human, Recombinant (His)	Human	HEK293
	Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as...
TMPY-03000	JAM-A Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as...
TMPY-01788	JAM-A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as...
TMPY-00865	JAM-A Protein, Human, Recombinant (hFc)	Human	HEK293
	Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as...
TMPH-00026	Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His)	Actinia equina	E. coli
	Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphin...
TMPY-00121	Vitronectin Protein, Human, Recombinant (His)	Human	HEK293
	Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis...
TMPY-01861	Vitronectin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis...
TMPY-00741	CXCL4 Protein, Human, Recombinant	Human	E. coli
	Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w...
TMPY-02975	CANT1 Protein, Human, Recombinant (hFc)	Human	HEK293
	CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yie...
TMPY-02710	CANT1 Protein, Human, Recombinant (His)	Human	HEK293
	CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yie...
TMPH-01333	Fibrinogen beta chain Protein, Human, Recombinant (His)	Human	E. coli
	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one o...
TMPJ-00045	Podoplanin Protein, Human, Recombinant (hFc)	Human	Human Cells
	Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weak...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ...
TMPJ-00055	Podoplanin Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmem...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His)	Human	Baculovirus-Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub...
TMPH-01857	PIK3CG Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-contai...
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)	Human	Human Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPY-02055	ENPP2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
------------------------ More ------------------------

PEAR1 Protein, Rat, Recombinant (His)

TMPY-00624

Species: Rat

Expression System: Baculovirus-Insect Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

Thrombopoietin Protein, Mouse, Recombinant (His)

TMPY-00939

Species: Mouse

Expression System: HEK293

Dermcidin Protein, Human, Recombinant (hFc)

TMPY-00545

Species: Human

Expression System: HEK293

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293

CD39 Protein, Mouse, Recombinant (His)

TMPY-02808

Species: Mouse

Expression System: Baculovirus-Insect Cells

CD39 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-05151

Species: Cynomolgus,Rhesus

Expression System: Baculovirus-Insect Cells

CD39 Protein, Human, Recombinant (His)

TMPY-01126

Species: Human

Expression System: Baculovirus-Insect Cells

ENPP2 Protein, Human, Recombinant (His)

TMPY-02778

Species: Human

Expression System: HEK293

ENPP2 Protein, Cynomolgus, Recombinant (His)

TMPY-00463

Species: Cynomolgus

Expression System: HEK293

Mer Protein, Human, Recombinant (His & hFc)

TMPY-00882

Species: Human

Expression System: HEK293

Mer Protein, Human, Recombinant

TMPY-04330

Species: Human

Expression System: HEK293

HIST3H2A Protein, Human, Recombinant

TMPY-02521

Species: Human

Expression System: E. coli

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)

TMPH-00322

Species: Calloselasma rhodostoma

Expression System: Yeast

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)

TMPH-00321

Species: Calloselasma rhodostoma

Expression System: E. coli

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)

TMPH-00323

Species: Calloselasma rhodostoma

Expression System: E. coli

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

TMPH-00320

Species: Calloselasma rhodostoma

Expression System: Yeast

P2Y1 Protein, Human, Recombinant (His)

TMPH-01822

Species: Human

Expression System: E. coli

SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)

TMPH-00216

Species: Bothrops jararaca

Expression System: E. coli

CD39 Protein, Rat, Recombinant (E. coli, His)

TMPH-03284

Species: Rat

Expression System: E. coli

CD39 Protein, Rat, Recombinant (His)

TMPH-03283

Species: Rat

Expression System: Baculovirus

SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)

TMPH-00215

Species: Bothrops jararaca

Expression System: E. coli

CXCL4 Protein, Pig, Recombinant (His & Myc)

TMPH-03121

Species: Sus scrofa (Pig)

Expression System: E. coli

SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)

TMPH-00217

Species: Bothrops leucurus

Expression System: E. coli

CD9 Protein, Mouse, Recombinant (His)

TMPH-02571

Species: Mouse

Expression System: in vitro E. coli expression system

PDIA6 Protein, Human, Recombinant (His)

TMPJ-01124

Species: Human

Expression System: Human Cells

Thrombopoietin Protein, Human, Recombinant (hFc)

TMPY-04201

Species: Human

Expression System: HEK293

Thrombopoietin Protein, Cynomolgus, Recombinant (His)

TMPY-01609

Species: Cynomolgus

Expression System: HEK293

SVTLE Protein, Protobothrops flavoviridis, Recombinant (His & Myc)

TMPH-03163

Species: Protobothrops flavoviridis

Expression System: E. coli

SVMP Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00214

Species: Bothrops atrox

Expression System: E. coli

GPVI Protein, Mouse, Recombinant (His)

TMPJ-00605

Species: Mouse

Expression System: Human Cells

JAM-A Protein, Rat, Recombinant (His)

TMPY-03161

Species: Rat

Expression System: HEK293

JAM-A Protein, Human, Recombinant (His)

TMPY-01035

Species: Human

Expression System: HEK293

JAM-A Protein, Rat, Recombinant (hFc)

TMPY-03000

Species: Rat

Expression System: HEK293

JAM-A Protein, Mouse, Recombinant (hFc)

TMPY-01788

Species: Mouse

Expression System: HEK293

JAM-A Protein, Human, Recombinant (hFc)

TMPY-00865

Species: Human

Expression System: HEK293

Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His)

TMPH-00026

Species: Actinia equina

Expression System: E. coli

Vitronectin Protein, Human, Recombinant (His)

TMPY-00121

Species: Human

Expression System: HEK293

Vitronectin Protein, Mouse, Recombinant (His)

TMPY-01861

Species: Mouse

Expression System: HEK293

CXCL4 Protein, Human, Recombinant

TMPY-00741

Species: Human

Expression System: E. coli

CANT1 Protein, Human, Recombinant (hFc)

TMPY-02975

Species: Human

Expression System: HEK293

CANT1 Protein, Human, Recombinant (His)

TMPY-02710

Species: Human

Expression System: HEK293

Fibrinogen beta chain Protein, Human, Recombinant (His)

TMPH-01333

Species: Human

Expression System: E. coli

Podoplanin Protein, Human, Recombinant (hFc)

TMPJ-00045

Species: Human

Expression System: Human Cells

PDE1C Protein, Human, Recombinant (His & GST)

TMPY-02977

Species: Human

Expression System: Baculovirus-Insect Cells

Podoplanin Protein, Mouse, Recombinant (hFc)

TMPJ-00055

Species: Mouse

Expression System: Human Cells

PDE2A Protein, Human, Recombinant (aa 215-900, His)

TMPY-02081

Species: Human

Expression System: Baculovirus-Insect Cells

PIK3CG Protein, Human, Recombinant (His & Myc)

TMPH-01857

Species: Human

Expression System: E. coli

MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

TMPJ-01143

Species: Human

Expression System: Human Cells

ENPP2 Protein, Mouse, Recombinant (His)

TMPY-02055

Species: Mouse

Expression System: HEK293

--------- More ---------

Cat No.	Product Name
L5400	Anti-Cardiovascular Disease Compound Library		1428 compounds
	A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1428