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Cat No. | Product Name | Synonyms | Targets |
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T7356 | PTP1B-IN-1 | PTP1B inhibitor | Phosphatase |
PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM) | |||
T12577 | PTP1B-IN-3 | Phosphatase | |
PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes. | |||
T67893 | PTP1B-IN-22 | Phosphatase | |
PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes. | |||
T4256 | PTP1B-IN-2 | Phosphatase | |
PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM). | |||
T12579 | RAMB4 | PTP1B-IN-9 | Proteasome |
RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity. | |||
T40745 | PTP1B-IN-13 | PTP1B-IN-13 | |
PTP1B-IN-13, a potent and selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), effectively targets the allosteric site, exhibiting an IC50 value of 1.59 μM. | |||
T24073 | PTP1B-IN-4 | NUN 17724,PTP1B-inhibitor-2,PTP1B IN 2,PTP1B-IN-2,PTP1B-inhibitor-4,FRJ,PTP1B inhibitor 4,NUN17724,PTP1B inhibitor 2,PTP1BIN2,NUN-17724 | Phosphatase |
PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes. | |||
T40835 | PTP1B-IN-14 | PTP1B-IN-14 | |
PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50) value of 0.72 μM. | |||
T12578 | (E,E)-RAMB4 | PTP1B-IN-8 | Phosphatase |
PTP1B-IN-8 is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B). | |||
T63435 | PTP1B-IN-16 | ||
PTP1B-IN-16 is a promising and selective benzimidazole derivative and an inhibitor of protein tyrosine phosphatase 1B (PTP1B) (Ki: 12.6 μM).PTP1B-IN-16 can be used to study type 2 diabetes. | |||
T63023 | PTP1B-IN-19 | ||
PTP1B-IN-19 (Compound 43) is a promising selective benzimidazole derivative as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 23.3 μM).PTP1B-IN-17 can be used to study type 2 diabetes. | |||
T63022 | PTP1B-IN-18 | ||
PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes. | |||
T63021 | PTP1B-IN-17 | ||
PTP1B-IN-17 (Compound 45) is a selective benzimidazole derivative with potential as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 30.2 μM).PTP1B-IN-17 can be used in the study of type 2 diabetes. | |||
T63739 | PTP1B-IN-15 | ||
PTP1B-IN-15 is a potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor that has shown research potential in type II diabetes and obesity. | |||
T61851 | PTP1B-IN-3 diammonium | ||
PTP1B-IN-3 diammonium is a highly effective and orally bioavailable inhibitor of the protein tyrosine phosphatase 1B (PTP1B) enzyme, with an IC50 value of 120 nM for both PTP1B and TCPTP. This compound exhibits potent an... | |||
T78702 | PTP1B/AKR1B1-IN-1 | Phosphatase | |
PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of 0.06 μM for PTP1B and 4.3 μM for AKR1B1. Additionally, it... | |||
T78703 | PTP1B/AKR1B1-IN-2 | Phosphatase | |
PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0 and 0.9 μM. This compound acts as an insulin mimetic and enhan... | |||
T4340 | SPI-112 | Phosphatase | |
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. | |||
T23133 | Pentamidine | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal | |
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. | |||
T9921 | Infliximab | TNF | |
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis. | |||
T7704 | KY-226 | Phosphatase | |
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,) | |||
T28410 | PHPS1 | PHPS-1,PHPS 1 | Phosphatase |
PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines. | |||
T1654 | Pentamidine isethionate | Pentamidine isethionate salt,Pentamidine diisethionate | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent. | |||
T23132 | Pentamidine dihydrochloride | MP-601205 dihydrochloride | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi... | |||
T22276 | Bis(maltolato)oxovanadium(IV) | BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) | Phosphatase , Others |
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i... | |||
T7381 | TCS 401 | Phosphatase | |
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 µM) | |||
T7084 | 2-Bromo-4'-hydroxyacetophenone | SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide | Phosphatase |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH... | |||
T9938 | RA371 | EX-A4742 | Others |
RA371 (EX-A4742) is a derivative of PTP1B-IN-8, an inhibitor of PTP1B. | |||
T4627 | SPI--112Me | Others | |
SPI--112Me, a prodrug of SPI-112, preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by more than 20-fold in cell-free assays. | |||
T22137 | PTP Inhibitor IV | Others | |
PTP Inhibitor IV is an effective protein tyrosine phosphatase (PTP) inhibitor, which can selectively inhibit DUSP14 phosphatase activity (IC50.5.21μm). PTP Inhibitor IV inhibited SHP-2, PTP1B, PTp-ε, PTP Meg-2, PTP-σ, PT... | |||
T13013 | Sodium stibogluconate | Stibogluconate trisodium nonahydrate | Phosphatase |
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent protein tyrosine phosphatase inhibitor. | |||
T16724 | Razuprotafib | AKB-9778 | Phosphatase , Others |
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury. | |||
T15166 | DPM-1001 | Phosphatase | |
DPM-1001 is an orally bioavailable and non-competitive protein-tyrosine phosphatase (PTP1B) inhibitor (IC50: 100 nM) with the anti-diabetic property. | |||
T11730 | JTT 551 | Others | |
JTT 551 can be used in the research of type 2 diabetes mellitus. JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosp... | |||
T15243 | Ertiprotafib | PTP 112 | Phosphatase , PPAR |
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ). | |||
T39167 | GS-493 | ||
GS-493, a highly specific protein tyrosine phosphatase SHP2 (PTPN11) inhibitor, exhibits remarkable potency with an IC50 of 71 nM. It displays 29- and 45-fold greater affinity towards SHP2 compared to its related counter... | |||
T25953 | PHPS1 Sodium | PHPS1 Na,PHPS1 Sodium salt | |
PHPS1 sodium is a potent and selective inhibitor of Shp2, with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively [1]. | |||
T35877 | MurA-IN-1 | ||
MurA-IN-1 (compound 1a), a PTPRR inhibitor, exhibits IC50 values of 0.09 μM for PTPRR, 0.23 μM for PTP1B, 0.75 μM for PTPN7, and 0.8 μM for PTPN5, respectively, targeting a family of human MAPK-specific protein tyrosine ... | |||
T69633 | TCS-401 | ||
TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B). | |||
T72216 | DPM-1001 trihydrochloride | ||
DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting an... | |||
T79845 | Anticancer agent 144 | Phosphatase | |
Compound 144 (also known as Anticancer Agent 144) is a potent inhibitor of both PTPN2 and PTP1B, exhibiting IC50 values of less than 2.5 nM, making it suitable for cancer research applications [1]. | |||
T41018 | CPT-157633 | ||
CPT-157633 is a difluoro-phosphonomethyl phenylalanine derivative that acts as a potent inhibitor of the enzyme PTP1B. It effectively prevents the development of glucose intolerance induced by binge drinking. | |||
TP1613 | [pTyr5] EGFR (988-993) | [pTyr5] EGFR 988-993 | |
[pTyr5] EGFR (988-993) is a compound obtained from the auto-phosphorylation site, Tyr992, located within the sequence of the epidermal growth factor receptor (EGFR 988-993). This compound is frequently found bound with t... | |||
T79844 | Anticancer agent 143 | Phosphatase | |
Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM. It is employed in cancer research [1]. | |||
T76019 | [pTyr5] EGFR (988-993) (TFA) | ||
[pTyr5] EGFR (988-993) TFA, originating from the Tyr992 autophosphorylation site of the epidermal growth factor receptor (EGFR 988-993), frequently forms a complex with catalytically inactive protein-tyrosine phosphate 1... | |||
T79479 | MptpB-IN-2 | Antibiotic | |
MptpB-IN-2 (compound 20), a selective inhibitor for mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB), exhibits half maximal inhibitory concentrations (IC50) of 0.64 μM for MptpB, 4.06 μM for MptpA, and 4... | |||
T71811 | Lobaric acid | ||
Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-f... | |||
T39677 | MY33-3 | MY33-3 | |
MY33-3 is a powerful and specific inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, demonstrating an IC50 value of approximately 0.1 μM. Moreover, MY33-3 exhibits inhibitory activity against PTP-1B with an IC... | |||
T10594 | BpV(phen) | PTEN | |
bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73072 | PTP1B-IN-20 | ||
PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor, exhibiting an IC50 of 1.05 μM, and demonstrates selectivity over TCPTP (T-cell protein tyrosine phosphatase), which has an IC50 of 78.0 μM. Th... | |||
T73073 | PTP1B-IN-21 | ||
PTP1B-IN-21 is a compound that functions as a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 μM), demonstrating a marked preference over the structurally similar T-cell protein tyrosine phosphat... | |||
T5708 | LUPENONE | Phosphatase , Parasite | |
Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhibitors with IC50 values of 15.11±1.23μM. | |||
TCS1372 | Atraric acid | Phosphatase , Androgen Receptor | |
Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of prostatic diseases. It inhibits PTP1B activity in a dose-depen... | |||
TN1990 | Norathyriol | 芒果 | Akt , DNA/RNA Synthesis , AMPK , PPAR |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
TN1470 | Cassiaside B2 | Phosphatase , MAO , 5-HT Receptor | |
Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the a... | |||
TN1956 | Mulberrofuran G | Phosphatase , HBV , Glucosidase | |
Mulberrofuran G is a small molecule compound from Morus alba L. It has anti-hepatitis B virus activity and protects against ischemic injury-induced cell death.Mulberrofuran G is a dual inhibitor of PTP1B and α-glucosidas... | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
TN1691 | Glabrol | P450 , NF-κB , NO Synthase , Acyltransferase | |
Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM. | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
T7028 | Licochalcone C | LICOCHALCONEC | Phosphatase , Antioxidant , Glucosidase |
Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit... | |||
TN1053 | Aloe-emodin-8-O-β-D-glucopyranoside | Aloe-emodin-8-O-beta-D-glucopyranoside | Phosphatase |
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |||
TN1859 | Licoflavone A | Phosphatase | |
Licoflavone A is a natural product isolated from the roots of Glycyrrhiza uralensis. | |||
T13740 | Isotanshinone IIA | Others | |
Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite. | |||
TN1775 | Isocryptotanshinone | ERK , JNK , STAT | |
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of ... | |||
TN3505 | Beta-Peltoboykinolic acid | Phosphatase | |
Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cytotoxic activity. | |||
T38587 | Chrysophanol triglucoside | ||
Chrysophanol triglucoside, an anthraquinone derivative obtained from Cassia obtusifolia, demonstrates inhibitory activity against protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase, with half-maximal inhibitory c... | |||
TN5400 | Aerugidiol | ||
Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B). | |||
T75603 | Cis-Ferulic acid 4-O-β-D-glucopyranoside | ||
Cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7), a phenolic glycoside derived from Nitraria sibirica, demonstrates antioxidant properties and a potent inhibitory effect on Phosphatase PTP1B [1]. | |||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid | Phosphatase | |
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | |||
TN2913 | 3-Acetoxy-11-ursen-28,13-olide | Phosphatase | |
3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A278... | |||
TN3335 | Abyssinone V | Phosphatase | |
Abyssinone V is a natural compound isolated from the stem bark of Erythrina melanacantha and an inhibitor of protein tyrosine phosphatase-1B (PTP1B). | |||
TN2288 | Uralenol | Others , Estrogen/progestogen Receptor , Tyrosinase | |
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate( IC50 =49.5 μM). Uralenol shows potent anti-prolif... | |||
T75495 | Rubrofusarin 6-O-β-D-glucopyranoside | ||
Rubrofusarin 6-O-β-D-glucopyranoside, a glycosidic derivative of Rubrofusarin, functions as an inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 87.36 μM. It is utilized in research investigating... | |||
TN3525 | Boehmenan | ERK , Phosphatase , EGFR , PARP , MEK , Wnt/beta-catenin , Akt , Caspase , STAT , p53 | |
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotox... | |||
TN1832 | Kanzonol C | Others , NF-κB , Tyrosinase | |
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it shows the inhibition of matrix metalloproteinase (MMP)-2 secre... | |||
TN4839 | Psidial A | Others | |
Psidial A shows activity to enzyme PTP1B; it also reduces tumor growth and stimulate uterus proliferation. | |||
TN4551 | Methyl orsellinate | Phosphatase , cAMP , Antifection | |
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain cal... | |||
T80008 | Stevisaliosides D | Phosphatase | |
Stevisaliosides D (Compound 5), extracted from the roots of Stevia serrata, exhibits inhibition of PTP1B with an IC50 of 31.8 μM and has applications in antidiabetic research [1]. | |||
TN4279 | Isoderrone | Tyrosinase | |
Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabe... | |||
T79985 | Cryptosporioptide A | Phosphatase | |
Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides. This compound effectively inhibits several enzymes including PTP1B, SHP2, CD... | |||
T3930 | Taraxerol acetate | Taraxeryl acetate | Phosphatase , HSV |
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activ... | |||
T80007 | Stevisalioside A | Phosphatase | |
Stevisalioside A (Compound 2), isolated from the roots of Stevia serrata, is an orally active antidiabetic agent that inhibits Protein Tyrosine Phosphatase 1B (PTP1B) with an IC50 value of 526.8 μM. It effectively lowers... | |||
TN4064 | Flavoglaucin | Phosphatase , IL Receptor , TNF , NOS , NF-κB , COX , Nrf2 , Prostaglandin Receptor , Autophagy | |
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor pr... | |||
TN2928 | Pygenic acid A | 3-Epicorosolic acid | |
3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid show... | |||
T38069 | Aquastatin A | ||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC... | |||
T3827 | Rhein-8-glucoside calcium | Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt | Phosphatase , Antibacterial |
Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... |