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Search Results for " ox-receptor "

Targets

17

Compounds

1

Natural Products

35

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4965 TCS-OX2-29 OX Receptor
TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays >250-fold selectivity for OX2 over OX1.
T5503 IPSU OX Receptor
IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.
T11186 EMPA OX Receptor
EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively)
T3177 Orexin 2 Receptor Agonist OX2R OX Receptor
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.
T1913 MK-3697 OX Receptor
MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
T16096 Filorexant MK-6096 OX Receptor
Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).
T5498 SB-649868 GSK649868 OX Receptor
SB-649868 (GSK649868) is a potent and selective orally active antagonist of orexin(pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).
T12877L Seltorexant JNJ-42847922 OX Receptor
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human a...
T2710 TCS 1102 OX Receptor
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
T3722 MK-1064 Urokinase inhibitor 1,MK 1064 OX Receptor
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
T6658 SB-408124 OX Receptor
SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.
T2613 Almorexant ACT 078573 OX Receptor
Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T6140 SB-334867 free base SB334867A free base,SB-334867,SB 334867,SB334867 OX Receptor
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.
T6155 Almorexant hydrochloride ACT-078573 hydrochloride,Almorexant HCl OX Receptor
Almorexant hydrochloride (ACT-078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T37112 YNT-185 dihydrochloride
Potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 μM at human OX1 expressed in CHO cells). Depo...
T77181 Revdofilimab
Revdofilimab (ABBV-368) is a human IgG1 monoclonal antibody that functions as an agonist against OX40, a member of the TNF receptor superfamily. OX40 is expressed on activated and memory T cell subsets as well as T regul...
T35463 (±)14(15)-EET (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
Cat No. Product Name Synonyms Targets
T2836 Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin MEK , PI3K , Endogenous Metabolite
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01423 OX40/TNFRSF4 Protein, Human, Recombinant (His) Human HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPJ-01458 OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ an...
TMPJ-00422 OX40/TNFRSF4 Protein, Mouse, Recombinant (His) Mouse Human Cells
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ an...
TMPK-01168 LOX-1 Protein, Mouse, Recombinant (His) Mouse HEK293
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
TMPK-00464 OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPY-06906 OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPY-05339 OX40/TNFRSF4 Protein, Human, Recombinant (hFc) Human HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPY-06875 OX40/TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPK-00169 OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00168 OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00167 OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi) Human HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00463 OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPY-04832 OX40L/TNFSF4 Protein, Human, Recombinant (hFc) Human HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-01302 CD200R Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05446 CD200 Protein, Human, Recombinant (hFc) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-04980 OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc) Mouse HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-04354 OX40L/TNFSF4 Protein, Human, Recombinant (mFc) Human HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-03875 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc) Cynomolgus HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-06018 OX40L/TNFSF4 Protein, Mouse, Recombinant (His) Mouse HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-04981 OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc) Mouse HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His) Human Human Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
TMPY-04066 LOX-1 Protein, Rat, Recombinant (His) Rat HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-02490 LOX-1 Protein, Human, Recombinant (His) Human HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-03351 LOX-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-03371 LOX-1 Protein, Rat, Recombinant (hFc) Rat HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-01261 CD200R Protein, Human, Recombinant (His & hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01092 CD200R Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01665 CD200R Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01353 CD200R Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01071 CD200 Protein, Human, Recombinant (His) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-06791 CD200 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03595 CD200 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-01160 CD200 Protein, Mouse, Recombinant (His) Mouse HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-05638 CD200 Protein, Human, Recombinant (hFc & Avi) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03380 CD200 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
OX40/TNFRSF4 Protein, Human, Recombinant (His)
TMPY-01423
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
TMPJ-01458
Species: Cynomolgus
Expression System: Human Cells
OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
TMPJ-00422
Species: Mouse
Expression System: Human Cells
LOX-1 Protein, Mouse, Recombinant (His)
TMPK-01168
Species: Mouse
Expression System: HEK293
OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00464
Species: Mouse
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06906
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (hFc)
TMPY-05339
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06875
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00169
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated
TMPK-00168
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi)
TMPK-00167
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)
TMPK-00463
Species: Mouse
Expression System: HEK293
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
TMPY-04832
Species: Human
Expression System: HEK293
CD200R Protein, Human, Recombinant (His)
TMPY-01302
Species: Human
Expression System: HEK293
CD200 Protein, Human, Recombinant (hFc)
TMPY-05446
Species: Human
Expression System: HEK293
OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc)
TMPY-04980
Species: Mouse
Expression System: HEK293
OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
TMPY-04354
Species: Human
Expression System: HEK293
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
TMPY-03875
Species: Cynomolgus
Expression System: HEK293
OX40L/TNFSF4 Protein, Mouse, Recombinant (His)
TMPY-06018
Species: Mouse
Expression System: HEK293
OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc)
TMPY-04981
Species: Mouse
Expression System: HEK293
CD200R1/CRTR2 Protein, Human, Recombinant (His)
TMPJ-00233
Species: Human
Expression System: Human Cells
LOX-1 Protein, Rat, Recombinant (His)
TMPY-04066
Species: Rat
Expression System: HEK293
LOX-1 Protein, Human, Recombinant (His)
TMPY-02490
Species: Human
Expression System: HEK293
LOX-1 Protein, Cynomolgus, Recombinant (His)
TMPY-03351
Species: Cynomolgus
Expression System: HEK293
LOX-1 Protein, Rat, Recombinant (hFc)
TMPY-03371
Species: Rat
Expression System: HEK293
CD200R Protein, Human, Recombinant (His & hFc)
TMPY-01261
Species: Human
Expression System: HEK293
CD200R Protein, Mouse, Recombinant (His & hFc)
TMPY-01092
Species: Mouse
Expression System: HEK293
CD200R Protein, Mouse, Recombinant (His)
TMPY-01665
Species: Mouse
Expression System: HEK293
CD200R Protein, Cynomolgus, Recombinant (His)
TMPY-01353
Species: Cynomolgus
Expression System: HEK293
CD200 Protein, Human, Recombinant (His)
TMPY-01071
Species: Human
Expression System: HEK293
CD200 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06791
Species: Human
Expression System: HEK293
CD200 Protein, Rhesus, Recombinant (His)
TMPY-03595
Species: Rhesus
Expression System: HEK293
CD200 Protein, Mouse, Recombinant (His)
TMPY-01160
Species: Mouse
Expression System: HEK293
CD200 Protein, Human, Recombinant (hFc & Avi)
TMPY-05638
Species: Human
Expression System: HEK293
CD200 Protein, Rhesus, Recombinant (hFc)
TMPY-03380
Species: Rhesus
Expression System: HEK293
TargetMol