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Search Results for " na+ ca2+ exchanger "

Targets

13

Compounds

Cat No. Product Name Synonyms Targets
T5850 Benzamil Benzamil (hydrochloride) Na+/Ca2+ Exchanger , Sodium Channel
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
T5457 SN 6 SN6 Calcium Channel , Na+/Ca2+ Exchanger
SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)
T1266 Terfenadine (±)-Terfenadine,MDL-991 Apoptosis , Potassium Channel , 5-HT Receptor , Caspase , Na+/Ca2+ Exchanger , HER , AChR , Histamine Receptor
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.
T14941 CGP37157 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one Na+/Ca2+ Exchanger
CGP37157 (7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one) is a Na+/Ca2+ exchanger inhibitor, inhibits Na+-induced Ca2+ release from mitochondria in guinea pig heart with IC50 of 0.8 μM.
T3508 SEA0400 SEA 0400,SEA-0400 Calcium Channel , Na+/Ca2+ Exchanger
SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger.
T6144 KB-R7943 mesylate KB-R7943 Na+/Ca2+ Exchanger , Autophagy
KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
T39195 YM-244769 dihydrochloride Calcium Channel
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys.
T9888 YM-244769 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- Calcium Channel
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec...
T11319 FR183998 free base Na+/Ca2+ Exchanger
FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger.
T12321 ORM-10103 Calcium Channel
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nM at -80 and 20 mV, respectively, and reduced early and delaye...
T68320 L594881 HCl
L594881, also known as 3',4'-Dichlorobenzamil or DCB, is an inhibitor of Na+/Ca2+ exchanger, Na+ transport and sarcoplasmic reticulum Ca2+ release channels. L594881 can inhibit Na+/Ca2+ exchanger, Na+ transport and sar...
T26383 3',4'-Dichlorobenzamil HCl
3',4'-Dichlorobenzamil HCl is an inhibitor of Na+ transport, Na+/Ca2+ exchanger, sarcoplasmic reticulum Ca2+ release channels.
T14857 Caldaret MCC-135 Others
Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.
TargetMol