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Search Result

Search Results for " monoamine oxidase b "

Targets

MAO

65

Compounds

14

Natural Products

1

Libraries

Cat No. Product Name Synonyms Targets
T8849 PF-9601N MAO
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
T22605 Bifemelane hydrochloride MAO , Monoamine Oxidase
Bifemelane hydrochloride is a MAO inhibitor
T7626 Budipine Others
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T18918 Azure B Azure B chloride MAO , Monoamine Oxidase
Azure B (Azure B chloride) is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombinant human MAO-A and MAO-B).
T1993 J-147 J147 Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T6073 OG-L002 Histone Demethylase , Monoamine Oxidase , HSV
OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.
T60806 Monoamine Oxidase B inhibitor 2
Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective inhibitor of monoamine oxidase B (MAO-B) (IC50 = 1.33 nM) which can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor...
T60656 Monoamine Oxidase B inhibitor 1
Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) that can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor 1 s...
T0300 Pargyline Pargylamine,Paragyline MAO , Monoamine Oxidase
Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.
T1578 Pargyline hydrochloride Pargylamine hydrochloride MAO , Monoamine Oxidase
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T67850 FCE 28073 MAO
FCE 28073 is a Monoamine oxidase B inibitor with IC50 of 0.45 uM.
T80799 WAY-620147 Monoamine Oxidase
WAY-620147 (compound 6), an N-(2-morpholinoethyl)nicotinamide derivative, acts as an inhibitor of monoamine oxidase (Monoamine Oxidase), demonstrating inhibitory activity against MAO-A and MAO-B with IC50 values of 26 μM...
T10079 MAO-IN-1 MAO
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
T77564 Coumarin102 Exciton 480
Coumarin102 (Exciton 480) is a fluorescent dye.Coumarin102 has weak inhibitory activity against Monoamine oxidase B, MAO-B and MAO-A and can be used to study neurological disorders.
T67789 Bazinaprine MAO
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong inhibitory effect on type A monoamine oxidase and weak inh...
T60932 MAO-B-IN-8 MAO
MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neuroinflammatory mediators. This compound is specifically des...
T24679 PSB-1434 PSB 1434,PSB1434 MAO
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
T24680 PSB-1491 MAO
PSB-1491 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 0.386 nM, >25000-fold selective versus MAO-A.
T60712 MAO-B-IN-17 MAO
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.
T67764 HMAO-B-IN-4 MAO
hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
T71934 Atibeprone
Atibeprone, also known as Lu 53439, is MAO-B inhibitor. The anticonvulsant activity of inhibitors of monoamine oxidase (MAO) was reported early after the development of irreversible MAO inhibitors such as tranylcypromine...
T60671 MAO-B-IN-9 Beta Amyloid , Serotonin Transporter , Monoamine Oxidase
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-9 has neuroprotective effects against Aβ1-42-induced neuron...
T67879 HMAO-B-IN-5 MAO , Monoamine Oxidase
hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be used in the study of Parkinson's disease. It is a promisin...
T38034 MAO-IN-M30 dihydrochloride M 30 dihydrochloride Monoamine Oxidase
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant...
T32535 Ladostigil TV-3326,Ladostigil,TV 3326,TV3326,Ladostigil free base Antioxidant , MAO , AChE
Ladostigil (Ladostigil free base) is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 values of 37.1 and 31.8 μM, respecti...
T6651L Safinamide EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743 MAO
Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. S...
T26562 Adarigiline
Adarigiline is a monoamine oxidase B inhibitor.
T24430 MAO-B Inhibitor 58 MAO-B Inhibitor-58
MAO-B inhibitor 58 is an effective, selective, and reversible inhibitor of monoamine oxidase B.
T24678 PSB-1410
PSB-1410 is a selective and competitive monoamine oxidase B inhibitor.
T68784 MD 780236
MD 780236 is a monoamine oxidase-B inhibitor.
T24565 NW-1772 NW 1772
NW-1772 is a highly potent and orally active inhibitor of monoamine oxidase B.
T71728 NW-1772 free base
NW-1772 free base is a monoamine oxidase B inhibitor.
T10154 MAO-B-IN-1 Others
MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.
T28798 SL-25.1188 SL25.1188
SL-25.1188 is a monoamine oxidase B (MAO-B) inhibitor. SL-25.1188 is characterized by reversible binding, high brain uptake, and very slow plasma metabolism in vivo.
T69680 Deprenyl
Deprenyl is a selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease.
T79229 ETAP Monoamine Oxidase
ETAP, a dual inhibitor of both monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B), exhibits antidepressant-like effects and is utilized in the research of major depressive disorder [1].
T72892 AChE/MAO-IN-1
AChE/MAO-IN-1 is a potent inhibitor of human acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), and monoamine oxidase B (MAO-B), demonstrating inhibitory concentrations (IC50) of 0.0248 μM, 0.0409 μM, and 0.1108 μ...
T61463 Monoamine oxidase/Aromatase-IN-1
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia...
T61131 MAO-B-IN-11
MAO-B-IN-11, also known as Compound 8c, is a highly potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-11 exhibits neuroprotective properties [1].
T61321 MAO-B-IN-12
MAO-B-IN-12 (Compound 16c) is a highly effective inhibitor of monoamine oxidase B (MAO-B), displaying significant potency with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-12 exhibits notable neuroprotective activity ...
T7626L Budipine Hydrochloride BY-701,BY 701,BY701,Parkinsan
Budipine is a non-dopaminergic antiparkinsonian drug. The primary action of budipine is an indirect dopaminergic effect as shown by facilitation of dopamine (DA) release, inhibition of monoamine oxidase type B (MAO-B) an...
T79761 MAO-B-IN-25 Monoamine Oxidase
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM for MAO-B and 0.5 nM for MAO-A [1].
T78859 MAO-B-IN-23 Monoamine Oxidase
MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM [1].
T5470 LAZABEMIDE Ro 19-6327 MAO , Monoamine Oxidase
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T60660 MAO-B-IN-14
MAO-B-IN-14 (Compound 9) is a potent and selective inhibitor of monoamine oxidase-B (MAO-B) with an IC 50 of 0.95 μM and a Ki of 0.55 μM for human MAO-B.
T60651 MAO-B-IN-16
MAO-B-IN-16 is a selective inhibitor of monoamine oxidase B (MAO-B ) (IC 50 = 1.55 μM) that can be used in the central nervous disorders study, for example, parkinson's disease [1].
T61830 MAO-B-IN-10
MAO-B-IN-10 (compound 4f) is a highly potent and selective inhibitor of MAO-B (monoamine oxidase-B). It effectively penetrates the blood-brain barrier and exhibits an IC50 of 5.3 μM. This compound demonstrates the abilit...
T78821 IHC3 Monoamine Oxidase
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site. It is utilized in the study of neurological diseases [1].
T81866 MAO-B-IN-27 Monoamine Oxidase
MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM, and is utilized in Parkinson's disease (PD) research [1].
T78648 MAO-B-IN-3 Monoamine Oxidase
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease resear...

Compounds

PF-9601N
T8849
Synonym:
Target: MAO
Bifemelane hydrochloride
T22605
Synonym:
Target: MAO, Monoamine Oxidase
Budipine
T7626
Synonym:
Target: Others
Azure B
T18918
Synonym: Azure B chloride
Target: MAO, Monoamine Oxidase
J-147
T1993
Synonym: J147
Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase
OG-L002
T6073
Synonym:
Target: Histone Demethylase, Monoamine Oxidase, HSV
Monoamine Oxidase B inhibitor 2
T60806
Synonym:
Target:
Monoamine Oxidase B inhibitor 1
T60656
Synonym:
Target:
Pargyline
T0300
Synonym: Pargylamine,Paragyline
Target: MAO, Monoamine Oxidase
Pargyline hydrochloride
T1578
Synonym: Pargylamine hydrochloride
Target: MAO, Monoamine Oxidase
FCE 28073
T67850
Synonym:
Target: MAO
WAY-620147
T80799
Synonym:
Target: Monoamine Oxidase
MAO-IN-1
T10079
Synonym:
Target: MAO
Coumarin102
T77564
Synonym: Exciton 480
Target:
Bazinaprine
T67789
Synonym:
Target: MAO
MAO-B-IN-8
T60932
Synonym:
Target: MAO
PSB-1434
T24679
Synonym: PSB 1434,PSB1434
Target: MAO
PSB-1491
T24680
Synonym:
Target: MAO
MAO-B-IN-17
T60712
Synonym:
Target: MAO
hMAO-B-IN-4
T67764
Synonym:
Target: MAO
Atibeprone
T71934
Synonym:
Target:
MAO-B-IN-9
T60671
Synonym:
Target: Beta Amyloid, Serotonin Transporter, Monoamine Oxidase
hMAO-B-IN-5
T67879
Synonym:
Target: MAO, Monoamine Oxidase
MAO-IN-M30 dihydrochloride
T38034
Synonym: M 30 dihydrochloride
Target: Monoamine Oxidase
Ladostigil
T32535
Synonym: TV-3326,Ladostigil,TV 3326,TV3326,Ladostigil free base
Target: Antioxidant, MAO, AChE
Safinamide
T6651L
Synonym: EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743
Target: MAO
Adarigiline
T26562
Synonym:
Target:
MAO-B Inhibitor 58
T24430
Synonym: MAO-B Inhibitor-58
Target:
PSB-1410
T24678
Synonym:
Target:
MD 780236
T68784
Synonym:
Target:
NW-1772
T24565
Synonym: NW 1772
Target:
NW-1772 free base
T71728
Synonym:
Target:
MAO-B-IN-1
T10154
Synonym:
Target: Others
SL-25.1188
T28798
Synonym: SL25.1188
Target:
Deprenyl
T69680
Synonym:
Target:
ETAP
T79229
Synonym:
Target: Monoamine Oxidase
AChE/MAO-IN-1
T72892
Synonym:
Target:
Monoamine oxidase/Aromatase-IN-1
T61463
Synonym:
Target:
MAO-B-IN-11
T61131
Synonym:
Target:
MAO-B-IN-12
T61321
Synonym:
Target:
Budipine Hydrochloride
T7626L
Synonym: BY-701,BY 701,BY701,Parkinsan
Target:
MAO-B-IN-25
T79761
Synonym:
Target: Monoamine Oxidase
MAO-B-IN-23
T78859
Synonym:
Target: Monoamine Oxidase
LAZABEMIDE
T5470
Synonym: Ro 19-6327
Target: MAO, Monoamine Oxidase
MAO-B-IN-14
T60660
Synonym:
Target:
MAO-B-IN-16
T60651
Synonym:
Target:
MAO-B-IN-10
T61830
Synonym:
Target:
IHC3
T78821
Synonym:
Target: Monoamine Oxidase
MAO-B-IN-27
T81866
Synonym:
Target: Monoamine Oxidase
MAO-B-IN-3
T78648
Synonym:
Target: Monoamine Oxidase
1 2
Cat No. Product Name Synonyms Targets
T4024 Norharmane 2-Azacarbazole,2,9-Diazafluorene,β-Carboline DNA , Endogenous Metabolite , Monoamine Oxidase
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
T3885 ROSIRIDIN 6'-O-Deacetylrosiridoside C,(-)-Rosiridin Others , Monoamine Oxidase
Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.
T13475 β-Aminopropionitrile 3-Aminopropionitrile,BAPN Others , Endogenous Metabolite
β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase.
T3158 Harmane Loturine,Harman,Aribine Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T3933 Jatrorrhizine Yatrorizine,neprotin MAO , 5-HT Receptor , Antibacterial , AChE
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...
TN1120 Osthenol MAO , Monoamine Oxidase
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ...
T40244 Methyl citrate
Methyl citrate, obtained from Opuntia ficus-indica var. saboten Makino fruits, serves as a potent Monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.23 mM.
TN3693 Confluentic acid Others
Confluentic acid shows selective inhibition of Monoamine oxidase B with IC50 value of 0.22 microM.
TN2790 2'-O-Methylperlatolic acid MAO
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN3116 5-Hydroxy-1-methoxyxanthone MAO , Antifection
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.
TN3726 Cudraflavone B IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b...
TC0022 Desoxypeganine Deoxypeganine AChE
Desoxypeganine (Deoxypeganine) is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.Desoxypeganine is being...
T79979 Methyl piperate Monoamine Oxidase
Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition of MAO-A (IC 50 27.1 μM) compared to MAO-B (IC 50 1.6 μM), ...
T37911 Cis-Resveratrol (Z)-Resveratrol
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, ...

Natural Products

Norharmane
T4024
Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline
Target: DNA, Endogenous Metabolite, Monoamine Oxidase
ROSIRIDIN
T3885
Synonym: 6'-O-Deacetylrosiridoside C,(-)-Rosiridin
Target: Others, Monoamine Oxidase
β-Aminopropionitrile
T13475
Synonym: 3-Aminopropionitrile,BAPN
Target: Others, Endogenous Metabolite
Harmane
T3158
Synonym: Loturine,Harman,Aribine
Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor
Jatrorrhizine
T3933
Synonym: Yatrorizine,neprotin
Target: MAO, 5-HT Receptor, Antibacterial, AChE
Osthenol
TN1120
Synonym:
Target: MAO, Monoamine Oxidase
Methyl citrate
T40244
Synonym:
Target:
Confluentic acid
TN3693
Synonym:
Target: Others
2'-O-Methylperlatolic acid
TN2790
Synonym:
Target: MAO
5-Hydroxy-1-methoxyxanthone
TN3116
Synonym:
Target: MAO, Antifection
Cudraflavone B
TN3726
Synonym:
Target: IκB/IKK, MAO, ROS, Akt, COX, PI3K, Nrf2, Autophagy
Desoxypeganine
TC0022
Synonym: Deoxypeganine
Target: AChE
Methyl piperate
T79979
Synonym:
Target: Monoamine Oxidase
cis-Resveratrol
T37911
Synonym: (Z)-Resveratrol
Target:
Cat No. Product Name
L9830 Anti-Parkinson's Disease Compound Library

908 compounds
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.

Libraries

Anti-Parkinson's Disease Compound Library
L9830
Compounds: 908
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