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Metabolism Mitochondrial Metabolism

Mitochondrial Metabolism

Cat No. product name
T9235 GW604714X GW604714X were found to be potent inhibitors of mitochondrial respiration supported by pyruvate
TN1586 Dihydrorotenone Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
T2930 α-Lipoic Acid α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.α-L...
T2A2532 Histidine Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintena...
T5337 IACS10759 IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
T7629 Olesoxime Olesoxime (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
T7486 Imeglimin hydrochloride Imeglimin hydrochloride prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
T8308 NL-1 NL-1 is a mitoNEET inhibitor with antileukemic effect.
T19428 Mito-TEMPO Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.
T9232 Mitochondrial fusion promoter M1 Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellula...
T10706 CCI-006 CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochon...
T13748 L-2-Hydroxyglutaric acid disodium L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine...
T8366 Mitochonic acid 5 Mitochonic acid 5 is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocy...
T8433 HQNO HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mit...
T8831 Elamipretide 2TFA Elamipretide is a novel mitochondrion-targeted antioxidant.
T22235 Lipoic acid Lipoic acid is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
T2498 Adjudin Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
GW604714X
T9235CAS 853953-65-8
GW604714X were found to be potent inhibitors of mitochondrial respiration supported by pyruvate
Dihydrorotenone
TN1586CAS 6659-45-6
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
α-Lipoic Acid
T2930CAS 62-46-4
α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.α-L...
histidine
T2A2532CAS 71-00-1
Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintena...
IACS10759
T5337CAS 1570496-34-2
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
Olesoxime
T7629CAS 22033-87-0
Olesoxime (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
Imeglimin hydrochloride
T7486CAS 775351-61-6
Imeglimin hydrochloride prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
NL-1
T8308CAS 188532-26-5
NL-1 is a mitoNEET inhibitor with antileukemic effect.
Mito-TEMPO
T19428CAS 1334850-99-5
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.
Mitochondrial fusion promoter M1
T9232CAS 219315-22-7
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellula...
CCI-006
T10706CAS 292053-42-0
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochon...
L-2-Hydroxyglutaric acid disodium
T13748CAS 63512-50-5
L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine...
Mitochonic acid 5
T8366CAS 1354707-41-7
Mitochonic acid 5 is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocy...
HQNO
T8433CAS 341-88-8
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mit...
Elamipretide 2TFA
T8831CAS 1334953-96-6
Elamipretide is a novel mitochondrion-targeted antioxidant.
Lipoic acid
T22235CAS 1200-22-2
Lipoic acid is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
Adjudin
T2498CAS 252025-52-8
Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.