Search Result

Search Results for " human immunodeficiency virus 1 "

Targets

Compounds

Natural Products

1732

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1809	TAT		HIV Protease
	TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept...		HIV Protease
T12715	Reverse transcriptase-IN-1		HIV Protease
	Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.		HIV Protease
T9063	Clathrin-IN-1		HIV Protease
	Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.		HIV Protease
T9039	HIV-1 Nef-IN-1		HIV Protease
	HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).		HIV Protease
T16276	NBD-556		HIV Protease
	NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.		HIV Protease
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T9212	IMB-301		Others , HIV Protease
	IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.		Others , HIV Protease
T15371	Gardiquimod		TLR , HIV Protease
	Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells...		TLR , HIV Protease
T11465	Lenacapavir	GS-6207	Others , HIV Protease
	Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.		Others , HIV Protease
T1883	Des(benzylpyridyl) Atazanavi		HIV Protease
	The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.		HIV Protease
T6255	Bromosporine		Epigenetic Reader Domain , CDK
	Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.		Epigenetic Reader Domain , CDK
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease
	FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective ...
T8233	BRD3308		Apoptosis , HIV Protease , HDAC
	BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.		Apoptosis , HIV Protease , HDAC
TP1149	HIV-1 Rev (34-50)	HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)	HIV Protease
	HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1.		HIV Protease
T20062	Thiamine disulfide	TDS,Daiomin,Algoneurina	HIV Protease , Endogenous Metabolite
	Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing...		HIV Protease , Endogenous Metabolite
T6246	Cobicistat	Tybost,GS-9350	P450 , HIV Protease
	Cobicistat (GS-9350) is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of ...		P450 , HIV Protease
T3199	PTACH	NCH-51,Cpd 51	HIV Protease , HDAC
	PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).		HIV Protease , HDAC
T14489	Azvudine	FNC,RO-0622	HCV Protease , HBV , HIV Protease , Reverse Transcriptase
	Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...		HCV Protease , HBV , HIV Protease , Reverse Transcriptase
T28578	Ro24-7429	Ro 24-7429,Ro-24-7429,Ro 247429	HIV Protease
	Ro24-7429 is an effective and orally active antagonist of HIV-1 transactivator protein Tat and an inhibitor of a runt-related transcription factor 1. Ro24-7429 has anti-HIV, antifibrotic, and anti-inflammatory effects.		HIV Protease
T11074	Dolutegravir intermediate-1	1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid	HIV Protease
	Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope...		HIV Protease
T9854	HIV-1 inhibitor-6	3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.		HIV Protease
T7700	Lersivirine	Lersivirine(UK 453061),UK-453061	HIV Protease , Reverse Transcriptase
	Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.		HIV Protease , Reverse Transcriptase
T6418	BMS-378806	BMS378806,BMS-806	gp120/CD4 , HIV Protease
	BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.		gp120/CD4 , HIV Protease
T0100L	Atazanavir	Zrivada,Reyataz,Latazanavir,BMS-232632	P450 , SARS-CoV , HIV Protease , P-gp
	Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.		P450 , SARS-CoV , HIV Protease , P-gp
T6474	Divalproex Sodium	Valproate semisodium,Epival	HDAC
	Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...		HDAC
T6420	BMS-707035		HIV Protease
	BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.		HIV Protease
T7212	Delavirdine mesylate	U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease , Reverse Transcriptase
	Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).		HIV Protease , Reverse Transcriptase
T27154	Dexelvucitabine	D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase
	Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.		Reverse Transcriptase
T0100	Atazanavir sulfate	BMS-232632,BMS-232632 sulfate	P450 , SARS-CoV , HIV Protease , P-gp
	Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS.		P450 , SARS-CoV , HIV Protease , P-gp
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T28255	Opaviraline	GW420867X,GW-867,HBY-1293,GW867,GW-420867X	HIV Protease
	Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.		HIV Protease
T27260	Emivirine	MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302	HIV Protease
	Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.		HIV Protease
T10570	Fostemsavir Tris	BMS-663068 Tris	HIV Protease
	Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and inter...		HIV Protease
T67804	KM-023		HIV Protease
	KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.		HIV Protease
T7779	Nelfinavir	AG1341	HIV Protease
	Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.		HIV Protease
T3435	Vicriviroc maleate	SCH-D (maleate),SCH-417690 (maleate)	HIV Protease , CCR
	Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment...		HIV Protease , CCR
T29037	UC-781	NSC 675186,UC781,UC 781	Antiviral , HIV Protease
	UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resis...		Antiviral , HIV Protease
T30527	BMS-488043	CHEMBL238103,UNII-MKS21EJ435,BMS 043,BMS488043,BMS 488043	HIV Protease
	BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+) lymphocytes.BMS-488043 is used for the treatment of immune d...		HIV Protease
T2393	Efavirenz	EFV,DMP 266,Sustiva,Stocrin,L-743726	HIV Protease , Reverse Transcriptase , Autophagy
	Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P...		HIV Protease , Reverse Transcriptase , Autophagy
T24374	L-708906	L708906,ARRY 142886,ARRY-142886,ARRY142886,L 708906
	L-708906 is the Human Immunodeficiency Virus Type 1 inhibitor.
T30536	BMS-663749	CHEMBL2219875,SCHEMBL2688950,BMS 663749,UNII-667A5745M0
	BMS-663749 is an attachment inhibitor of human immunodeficiency virus type 1 (HIV-1).
T15483	LEDGIN6	HIV-1 integrase inhibitor 2	Others
	HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.		Others
T70657	Ormosinine
	Ormosinine is an inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
T71763	BMMP
	BMMP is a novel postentry inhibitor of human immunodeficiency virus type 1 (HIV-1) replication.
T70546	HI-346
	HI-346 is a potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1).
T70586	S 2720
	S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.
T30585	Brecanavir	GW-640385,GW-640385X,UNII-E367I8C7FI,CHEMBL206031,GW-0385
	Brecanavir is a tyrosyl-based arylsulfonamide, high affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type 1.
T24794	SJ-3366	SJ 3366
	SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.
T23585	5-Et-ddU	ddEtUrd,D2EtU,5-Ethyl-2',3'-dideoxyuridine
	5-Et-ddU, Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
T34974	U 104489	U104489,PNU-104489,PNU 104489,PNU104489,U-104489
	U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.

Compounds

Reverse transcriptase-IN-1

Target: HIV Protease, Src, Hck

IMB-301

T9212

Synonym:

Target: Others, HIV Protease

Gardiquimod

T15371

Synonym:

Target: TLR, HIV Protease

Lenacapavir

T11465

Synonym: GS-6207

Target: Others, HIV Protease

Des(benzylpyridyl) Atazanavi

Target: Epigenetic Reader Domain, CDK

FGI-106 tetrahydrochloride

T11281L

Synonym:

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

BRD3308

T8233

Synonym:

Target: Apoptosis, HIV Protease, HDAC

HIV-1 Rev (34-50)

TP1149

Synonym: HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)

Target: HIV Protease

Thiamine disulfide

T20062

Synonym: TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Cobicistat

T6246

Synonym: Tybost,GS-9350

Target: P450, HIV Protease

PTACH

T3199

Synonym: NCH-51,Cpd 51

Target: HIV Protease, HDAC

Azvudine

T14489

Synonym: FNC,RO-0622

Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase

Ro24-7429

T28578

Synonym: Ro 24-7429,Ro-24-7429,Ro 247429

Target: HIV Protease

Dolutegravir intermediate-1

T11074

Synonym: 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Target: HIV Protease

HIV-1 inhibitor-6

T9854

Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

Target: HIV Protease

Lersivirine

T7700

Synonym: Lersivirine(UK 453061),UK-453061

Target: HIV Protease, Reverse Transcriptase

BMS-378806

T6418

Synonym: BMS378806,BMS-806

Target: gp120/CD4, HIV Protease

Atazanavir

T0100L

Synonym: Zrivada,Reyataz,Latazanavir,BMS-232632

Target: P450, SARS-CoV, HIV Protease, P-gp

Divalproex Sodium

T6474

Synonym: Valproate semisodium,Epival

Synonym: U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)

Target: HIV Protease, Reverse Transcriptase

Dexelvucitabine

T27154

Synonym: D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC

Target: Reverse Transcriptase

Atazanavir sulfate

T0100

Synonym: BMS-232632,BMS-232632 sulfate

Target: P450, SARS-CoV, HIV Protease, P-gp

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Opaviraline

T28255

Synonym: GW420867X,GW-867,HBY-1293,GW867,GW-420867X

Target: HIV Protease

Emivirine

T27260

Synonym: MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302

Target: HIV Protease

Fostemsavir Tris

T10570

Synonym: BMS-663068 Tris

Synonym: SCH-D (maleate),SCH-417690 (maleate)

Target: HIV Protease, CCR

UC-781

T29037

Synonym: NSC 675186,UC781,UC 781

Target: Antiviral, HIV Protease

BMS-488043

T30527

Synonym: CHEMBL238103,UNII-MKS21EJ435,BMS 043,BMS488043,BMS 488043

Target: HIV Protease

Efavirenz

T2393

Synonym: EFV,DMP 266,Sustiva,Stocrin,L-743726

Target: HIV Protease, Reverse Transcriptase, Autophagy

L-708906

T24374

Synonym: L708906,ARRY 142886,ARRY-142886,ARRY142886,L 708906

Target:

BMS-663749

T30536

Synonym: CHEMBL2219875,SCHEMBL2688950,BMS 663749,UNII-667A5745M0

Target:

LEDGIN6

T15483

Synonym: HIV-1 integrase inhibitor 2

Synonym: GW-640385,GW-640385X,UNII-E367I8C7FI,CHEMBL206031,GW-0385

Synonym: ddEtUrd,D2EtU,5-Ethyl-2',3'-dideoxyuridine

Target:

U 104489

T34974

Synonym: U104489,PNU-104489,PNU 104489,PNU104489,U-104489

Target:

Cat No.	Product Name	Synonyms	Targets
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
T4962	Zingibroside R1	Ginsenoside Z-R1	HIV Protease
	Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity.		HIV Protease
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T22468	1-Deoxymannojirimycin hydrochloride		Others , Influenza Virus , HIV Protease
	α-mannosidase I inhibitor		Others , Influenza Virus , HIV Protease
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T4537	Cholic acid sodium	SodiumCholate	HIV Protease , Endogenous Metabolite
	Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.		HIV Protease , Endogenous Metabolite
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
TL0006	Cichoric Acid	Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species , HIV Protease
	Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...		Reactive Oxygen Species , HIV Protease
TN2231	Soyasaponin II		Influenza Virus , HIV Protease , HSV
	Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.		Influenza Virus , HIV Protease , HSV
TN4109	Ganolucidic acid A		HIV Protease
	Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of...		HIV Protease
TMA1012	Ganoderiol F		Androgen Receptor , HIV Protease , Autophagy
	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced...		Androgen Receptor , HIV Protease , Autophagy

Natural Products

Diphyllin

TN1103

Synonym:

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Zingibroside R1

T4962

Synonym: Ginsenoside Z-R1

Target: HIV Protease

L-Chicoric Acid

T6S2391

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid

Target: Others, HIV Protease

1-Deoxymannojirimycin hydrochloride

T22468

Synonym:

Target: Others, Influenza Virus, HIV Protease

α-Lipoic Acid

T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Cholic acid sodium

T4537

Synonym: SodiumCholate

Target: HIV Protease, Endogenous Metabolite

Rosamultin

T5783

Synonym:

Target: Antioxidant, HIV Protease

Cichoric Acid

TL0006

Synonym: Dicaffeoyltartaric acid,Chicoric Acid

Target: Reactive Oxygen Species, HIV Protease

Soyasaponin II

TN2231

Synonym:

Target: Influenza Virus, HIV Protease, HSV

Target: Androgen Receptor, HIV Protease, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-02257	CCL14 Protein, Human, Recombinant (His)	Human	E. coli
	CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is...
TMPY-02468	CCL14 Protein, Human, Recombinant (aa 28-93, His)	Human	E. coli
	CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is...
TMPY-02357	CLEC-2 Protein, Human, Recombinant (His)	Human	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPH-01555	IFITM1 Protein, Human, Recombinant (GST)	Human	E. coli
	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against ...
TMPY-03963	CALCB Protein, Human, Recombinant (mFc)	Human	HEK293
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, ...
TMPH-01249	ADAR Protein, Human, Recombinant (GST)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293

TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01949	CD19 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01386	CD155/PVR Protein, Human, Recombinant (His)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-04493	BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01055	IL-4R Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03524	B7-H4 Protein, Human, Recombinant (His)	Human	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPY-01834	CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)	Mouse	HEK293
	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional...
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)	Human	Baculovirus-Insect Cells
	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular protei...
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05275	CD79B Protein, Human, Recombinant (His)	Human	HEK293

TMPY-00381	PSMA Protein, Human, Recombinant (His)	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-01431	L1CAM Protein, Human, Recombinant (His)	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-05357	GCDH Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells

TMPY-00828	Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)	Human	HEK293
	Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfat...
TMPY-04730	LAG-3 Protein, Human, Recombinant (His)	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-01885	Human RSV (B1) glycoprotein G/RSV-G Protein (His)	RSV	HEK293
	Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneum...
TMPY-01475	Jagged 1 Protein, Human, Recombinant (His)	Human	HEK293
	Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmemb...
TMPY-05306	TRIM21 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells

TMPY-05131	PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01483	SLAMF7 Protein, Human, Recombinant (His)	Human	HEK293
	SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-01446	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His)	Human	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-04165	FGFR3 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPY-02078	HtrA2/Omi Protein, Human, Recombinant (His)	Human	E. coli
	Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPK-00347	Serum Albumin Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands i...
TMPY-02205	Beta-Catenin Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p...
TMPY-00939	Thrombopoietin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-01126	CD39 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc)	Human	HEK293

TMPY-00853	IL-1RA Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPK-00942	DLK1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu...
TMPY-01257	UPAR/PLAUR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
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