T0013 |
Mecarbinate |
Mecarbinate is arbidol hydrochloride's chemical intermediate. |
T0392 |
Artemisinin |
Artemisinin is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organi...
|
T10067 |
2',5-Difluoro-2'-deoxycytidine |
2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA. |
T12033 |
Micrococcin P1 |
Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor(EC50 range of 0.1-0.5 μM) |
T12956 |
Sofosbuvir impurity A |
Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity. |
T12961 |
Sofosbuvir impurity F |
Sofosbuvir impurity F is a diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12962 |
Sofosbuvir impurity G |
Sofosbuvir impurity G is a diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12963 |
Sofosbuvir impurity H |
Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is a diastereoisomer of Sofosbuvir.Sofosbuvir is a...
|
T12964 |
Sofosbuvir impurity I |
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12965 |
Sofosbuvir impurity J |
Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12966 |
Sofosbuvir impurity K |
Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12967 |
Sofosbuvir impurity L |
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12968 |
Sofosbuvir impurity M |
Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T12969 |
Sofosbuvir impurity N |
Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
T13281 |
Valopicitabine |
Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic...
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T14095 |
ACH-806 |
ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. |
T14555 |
BI-1230 |
BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine prote...
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T14667 |
BLT-1 |
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor. |
T15573 |
Inarigivir soproxil |
Inarigivir soproxil is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of...
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T16088 |
MK-0608 |
MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay). |
T1643 |
Penciclovir |
Penciclovir is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subs...
|
T16675 |
PSI-352938 |
PSI-352938 is an inhibitor of hepatitis C virus nucleotide. |
T16774 |
RO-9187 |
RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM). |
T17029 |
Tegobuvir |
Tegobuvir is a specific and covalent HCV NS5B polymerase inhibitor. |
T1786 |
Daclatasvir dihydrochloride |
Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiv...
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T19862 |
Voxilaprevir |
Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease. |
T2117 |
PSI6206 |
PSI-6206 (RO2433) is a selective HCV RNA polymerase inhibitor. |
T2162 |
Maribavir |
Maribavir is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the vir...
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T2774 |
Lycorine chloride |
Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity. |
T3226 |
Paritaprevir |
Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein ...
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T3334 |
Velpatasvir |
Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barri...
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T3489 |
Dasabuvir |
Dasabuvir is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activit...
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T4197 |
HZ1157 |
HZ-1157 is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease. |
T4203 |
Ledipasvir acetone |
Ledipasvir (GS5885) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection. |
T4474 |
Asunaprevir |
Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor. |
T4544 |
Elbasvir |
Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infe...
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T4547 |
Grazoprevir |
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0....
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T4686 |
Simeprevir |
Simeprevir is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. |
T4988 |
Boceprevir |
Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell...
|
T5126 |
Glecaprevir |
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM). |
T5127 |
ABT530 |
ABT-530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6. |
T5396 |
Letermovir |
Letermovir (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex. |
T5938 |
4-Phenoxybenzylamine |
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a . |
T6025 |
Danoprevir |
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV). |
T6190 |
Telaprevir |
Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM). |
T6200 |
Ledipasvir |
Ledipasvir is a Hepatitis C Virus NS5A Inhibitor. The mechanism of action of ledipasvir is as a P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein I...
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T6229 |
Daclatasvir |
Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a...
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T6676 |
Sofosbuvir |
Sofosbuvir is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic...
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T6729 |
Lomibuvir |
VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM. |
T7158 |
Ombitasvir |
Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against ...
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T7215 |
NM107 |
NM107 is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, NM 107 in the wild-...
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TN1138 |
gamma-Fagarine |
gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)...
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TN1703 |
Glycyrin |
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice. |
TN2089 |
Platycodin D3 |
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway...
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TN2252 |
Syrosingopine |
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase i...
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TN3438 |
Arborinine |
Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± ...
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TN3809 |
Dehydrojuncusol |
Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is act...
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TN4404 |
Ladanein |
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radi...
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TN5079 |
Sulochrin |
Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytoto...
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TN5263 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic ef...
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TQ0030 |
Tomeglovir |
Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV). |
TQ0064 |
Peretinoin |
Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR. |
TQ0090 |
Nesbuvir |
Nesbuvir (HCV-796) is a nonnucleoside inhibitor of the HCV nonstructural protein 5B (NS5B) polymerase. |
TQ0122 |
VCH-916 |
VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase. |
TQ0162 |
R-1479 |
R-1479 is an HCV replication inhibitor in the HCV subgenomic replicon system (IC50: 1.28 μM). |