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Search Result

Search Results for " glutathione-reductase "

11

Compounds

2

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T78342 Glutathione reductase EC 1.6.4.2
Glutathione reductase (EC 1.6.4.2) is an enzyme that ensures the availability of reduced glutathione [1].
T5481 TRi-1 Others
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
T10339 Antitrypanosomal agent 1 Parasite
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
T8452 Dantrolene Others
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
T60446 LCS3 Apoptosis , Glutathione reductase
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in...
TP1604L Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base) Others
Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active...
T69828 Melarsen oxide
Melarsen oxide is a glutathione reductase inhibitor.
T69010 Hemustine
Hemustine is an inhibitor of human glutathione reductase and widely used as an anti-tumor agent.
T67498 3-Amino-1,2,4-triazole Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B Reactive Oxygen Species
3-Amino-1,2,4-triazole (Trapidil impurity B) is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves increasing the activities of glutathi...
TP1604 Thioredoxin reductase peptide
Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi...
T36173 L-Glutathione, oxidized (sodium salt)
Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized fo...
Cat No. Product Name Synonyms Targets
T5372 L-SelenoMethionine L-(+)-Selenomethionine Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
T36448 (E)-Ajoene
(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fu...

Natural Products

L-SelenoMethionine
T5372
Synonym: L-(+)-Selenomethionine
Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite
(E)-Ajoene
T36448
Synonym:
Target:

Recombinant Proteins

Species：
Human (3)
Expression System：
E. coli (2)
Yeast (1)
Tag：
N-terminal 6xHis-tagged (2)
His (1)
Cat No. Product Name Species Expression System
TMPY-03605 Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His) Human E. coli
Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatica...
TMPH-01040 CBR1 Protein, Human, Recombinant (His) Human Yeast
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction...
TMPH-01039 CBR1 Protein, Human, Recombinant (E. coli, His) Human E. coli
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction...
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