Glucosidase

Glucosidase belongs to the glycoside hydrolase family of enzymes and plays a crucial role in breaking down glucosidic bonds to release glucose. Glucosidase is essential for sugar metabolism in organisms, found across a wide range of sources and present in almost all cellular structures that utilize carbohydrates for energy. This enzyme comes in two main types: β-glucosidase, involved in cellulose metabolism and various physiological pathways, and α-glucosidase, which directly participates in starch and glycogen metabolism. Dysfunctions in these enzymes can lead to metabolic disorders. Moreover, glucosidase serves as a target for various drugs and inhibitors aimed at regulating sugar metabolism in the human body.

Cat. No.	Product name	CAS No.	Purity
TWS0787	Oroxin A	31567-75-6
TWS0787	Oroxin A (Baicalin-7-glucoside) is a partial PPARγ agonist that can activate PPARγ transcriptional activation in vitro and in vivo. Oroxin A also exhibited inhib...
T78671	Glucocerebrosidase-IN-1 hydrochloride	2279945-77-4	98%
T78671	Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent, selective GCase (glucocerebrosidase) inhibitor with IC50 and Ki values of 29.3 μM and 18.5 μM, ...
T78731	α-Glucosidase-IN-26		98%
T78731	α-Glucosidase-IN-26 (Compound 7i), with an IC50 value of 4.63 µM, functions as an α-glucosidase inhibitor and is utilized in research related to type 2 diabetes ...
T78740	α-Glucosidase-IN-28	2949513-10-2	98%
T78740	α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM. It interacts with the enzyme's original binding ...
T78741	α-Glucosidase-IN-29	2949513-11-3	98%
T78741	α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM. This compound is utilized in the re...
T78794	α-Glucosidase-IN-31		98%
T78794	α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and antidia...
T78864	α-Glucosidase-IN-33		98%
T78864	α-Glucosidase-IN-33 (compound 7c), with an IC50 of 2.39 μM, is a potent inhibitor of α-glucosidase and is relevant in research on type 2 diabetes and hyperglycem...
T78865	α-Glucosidase-IN-34		98%
T78865	α-Glucosidase-IN-34 (compound 7f) is a potent inhibitor of α-glucosidase, exhibiting an IC50 of 2.90 μM, and is applicable in research related to type 2 diabetes...
T78878	α-Amylase/α-Glucosidase-IN-5		98%
T78878	α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with I...
T78881	α-Glucosidase-IN-36		98%
T78881	α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65 ...
T79225	α-Amylase/α-Glucosidase-IN-3		98%
T79225	α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM, ...
T79237	α-Glucosidase-IN-27		98%
T79237	α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1]....
T79259	α-Glucosidase-IN-25		98%
T79259	α-Glucosidase-IN-25 (Compound (R)-8k) serves as a competitive inhibitor for α-glucosidase, demonstrating an inhibitory concentration 50 (IC50) of 1.19μM, making ...
T79318	α-Glucosidase-IN-30		98%
T79318	α-Glucosidase-IN-30 (compound 8c) is a potent, orally active competitive inhibitor of α-glucosidase, exhibiting a K i of 40.0 µM and an IC50 of 49.0 µM. It is no...
T79402	α-Amylase/α-Glucosidase-IN-4		98%
T79402	α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50 ...
T79644	Antidiabetic agent 2		98%
T79644	Compound 56 (Antidiabetic agent 2) is a glucose-uptake promoter that inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase, with IC50 values of 0.036, 0.042, 0.24...
T79700	α-Glucosidase-IN-32		98%
T79700	α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM. It forms a c...
T79910	Cyclophellitol aziridine	136861-97-7	98%
T79910	Cyclophellitol aziridine, an analogue of cyclophenol, serves as a potent inhibitor of β-glucosidase [1].
T79937	Mortatarin F		98%
T79937	Mortatarin F (Compound 1), a renyleted flavonoid derived from mulberry leaves, functions as an α-glucosidase inhibitor with an IC50 value of 8.7 μM, making it pe...
T79938	Mortatarin G		98%
T79938	Mortatarin G (compound 3), a prenylated flavonoid derived from mulberry leaves, demonstrates potent α-glucosidase inhibition, evidenced by an IC50 value of 20.4±...