| T9424 |
Temgicoluril |
Temgicoluril acts on GABA Receptor.
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| T3927 |
Phellopterin |
Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration f...
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| T4655 |
Pipequaline |
Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure t...
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| T4688 |
Pipequaline hydrochloride |
Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure t...
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| TMS0418 |
Dihydroergotoxine mesylate |
It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
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| T4522 |
SSD114 hydrochloride |
SSD114 is a novel GABAB receptor positive allosteric modulator.
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| T3S2259 |
Methyl eugenol |
1. Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcino...
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| T7064 |
Valproic Acid |
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
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| T4363 |
CGP 52432 |
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
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| T5330 |
Fluralaner |
Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes ...
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| T4440 |
Saclofen |
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7...
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| T4176 |
Rac-BHFF |
Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectivel...
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| T0675 |
Topiramate |
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
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| T2339 |
Apalutamide |
Apalutamide is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
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| T2067 |
NS 11394 |
NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > ...
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| T2983 |
3,4,5-Trimethoxycinnamic acid |
3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex...
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| T4993 |
Afloqualone |
Afloqualone is a agonist of GABA receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. Afloqualone is an analogue of m...
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| T5375 |
Loreclezole |
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
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| T1673 |
Acamprosate calcium |
Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.
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| TQ0040 |
ONO-8590580 |
ONO-8590580 is a negative allosteric modulator of GABAA α5.
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| T8193 |
Thujone |
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
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| T7803 |
Gaboxadol (hydrochloride) |
Gaboxadol (hydrochloride) is a GABAA receptor agonist.
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| T7793 |
6-(4-Methoxyphenyl)-3-pyridazinamine |
6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
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| T7794 |
Zuranolone |
Zuranolone is an agonist of GABAA receptor.
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| TQ0151 |
L-655708 |
L-655708 is an effective inverse agonist of the α5 subunit-selective GABAA receptor (Ki: 0.45 nM).
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| TQ0119 |
Cirsimaritin |
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors. It has antibacterial, anti-inflammation, anti-tumor, antioxidant, renal protection.
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| TQ0023 |
Lorediplon |
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
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| T5734 |
(+)-BORNEOL |
(+)-BORNEOL is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of ...
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| T7557 |
Guvacine hydrochloride |
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
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| T7721 |
GANAXOLONE |
Ganaxolone is a positive allosteric modulator of the action of the GABAA receptor, acts on well-characterized targets in the brain known to have anxiolytic and a...
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| T7595 |
L-DAB HBR |
L-DAB HBR is an inhibitor of GABA transaminase (IC50 > 500 μM).
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| T7622 |
Gabazine |
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
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| T7136 |
AZD6280 |
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
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| T7165 |
Basmisanil |
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment o...
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| T5880 |
Aminooxyacetic acid hemihydrochloride |
Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
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| T1240 |
Flumazenil |
Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS),...
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| T0169 |
Nefiracetam |
Nefiracetam are underway in Phase 2 trials. Nefiracetam, a GABAergic、 cholinergic、and monoaminergic neuronal system enhancer, is used for Ro 5-4864-induced c...
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| T8036 |
6-Methylflavone |
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
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| T7000 |
Tiagabine hydrochloride |
Tiagabine Hydrochloride is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric aci...
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| T2775 |
Baicalin |
Baicalin is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.
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| T1860 |
AWD 131-138 |
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
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| T0349 |
Riluzole |
Riluzole is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LA...
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| T2749 |
Ginkgolide A |
Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inf...
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| T3644 |
U93631 |
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GA...
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| T0954 |
Anestan |
Halothane is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adeq...
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| T0128L |
Vigabatrin Hydrochloride |
Vigabatrin HCl is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA ...
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| T1089 |
Etomidate |
Etomidate is a GABAA receptor agonist, with a short-acting sedative, hypnotic, and general anesthetic properties.
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| T0024 |
Primidone |
Primidone is an anticonvulsant of the pyrimidinedione class.
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| T2196 |
Fipronil |
Fipronil is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central...
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| T2407 |
Tiagabine |
Tiagabine is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
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| T1065 |
Baclofen |
Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen act...
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| T0627 |
Beta-Alanine |
β-Alanine is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating...
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| T2990 |
Phenibut |
Phenibut is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).
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| T2998 |
Dihydromyricetin |
Dihydromyricetin is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of ...
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| T0710 |
L-Cycloserine |
L-cycloserine irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in inc...
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| T0958 |
Penicillin G sodium salt |
Penicillin G sodium is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effe...
|
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| T6507 |
Gabapentin HCl |
Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
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| T6355 |
(R)-baclofen |
(R)-baclofena, a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.
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| T2940 |
6-Hydroxyflavone |
6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prioni...
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| T1396 |
Bemegrid |
Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.
|
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| T1128 |
Oxiracetam |
Oxiracetam, a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
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| T0128 |
Vigabatrin |
Vigabatrin, an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate transaminase responsible for the catabolism of γ-aminobutyri...
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| T0702 |
Gabapentin |
Gabapentin is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical Activity.
|
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| T3403 |
Glabridin |
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
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| T0883 |
Homotaurine |
Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. H...
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| T0048 |
Nikethamide |
Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth cen...
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| T0508 |
4-Aminobutyric acid |
4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
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| T1413 |
Pentetrazol |
Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.
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| T0051 |
Urethane |
Urethane was an antineoplastic agent .Now is used for other medicinal purposes.
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| T3318 |
Wogonoside |
Wogonoside acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
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| T2850 |
(+)-Bicuculline |
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated...
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| T3741 |
(-)-borneol |
(-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.
|
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| T8268 |
6,2'-Dihydroxyflavone |
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
|
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| T8040 |
Cholesterol myristate |
Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic ace...
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| T9255 |
Zolpidem tartrate |
Zolpidem is a prescription medication used for the treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the...
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| T17306 |
Arbaclofen hydrochloride |
Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to...
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| T8630 |
Baclofen hydrochloride |
Baclofen hydrochloride is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, es...
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| T8568 |
Suritozole |
Suritozole is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
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| T8639 |
Phenibut (hydrochloride) |
Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulate...
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| T8572 |
CL 218872 |
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 ...
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| T22348 |
Isonipecotic acid |
Isonipecotic acid is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
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| T22301 |
L-838417 D9 |
L-838417 is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
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| T17215 |
Valnoctamide |
Valnoctamide inhibits benzodiazepine-refractory status epilepticus. Valnoctamide acts directly on GABAA receptors.
|
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| T9113 |
Myristicin |
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also ...
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| T17144 |
TPA 023 |
TPA 023 is an agonist of the GABAA α2/α3 subtype-selective (Ki: 0.19-0.41 nM).
|
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| T12867L |
SCH 50911 |
SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, ...
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| T16811 |
RWJ-51204 |
RWJ-51204 is a partial agonist of GABA(A) receptor (Ki: 0.2-2 nM).
|
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| T16794 |
RO 4938581 |
RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3...
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| T11822 |
LAU159 |
LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
|
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| T16717 |
Radequinil |
Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
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| T4S1616 |
Sanggenone D |
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamm...
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|
| TN3351 |
Aflatrem |
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocam...
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| T15775 |
Lotilaner |
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA rec...
|
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| T20242 |
Chlorothymol |
Chlorothymol is a disinfectant used in oral.
|
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| TN6773 |
Acetoxyvalerensre |
Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
|
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| TN6773 |
Acetoxyvalerensre |
Acetoxyvalerensre (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
|
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| TN6765 |
Etiocholanone |
Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid p...
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| T21802 |
Etomidate hydrochloride |
Etomidate hydrochloride is a potent agonist of GABAA receptor. It is a neurological drug and effective parenteral medication and has the potential for management...
|
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| T8971 |
Imidazenil |
Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
|
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| T8887 |
2'MeO6MF |
2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved function...
|
|
| T8664 |
SSD114 hydrochloride |
SSD114 hydrochloride is a GABAB receptor positive allosteric modulator.
|
|
| TN3702 |
(-)-Corlumine |
Corlumine exhibits spasmolytic and GABA antagonist activity.
|
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| T23104 |
Ocinaplon |
Ocinaplon is a GABAA receptors modulator.
|
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| TN5147 |
Tilifodiolide |
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
|
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| TN5089 |
Tabernanthine |
Tabernanthine shows affinity for opiate receptors, it can decrease morphine and cocaine self-administration in rats, it may be effective in treating addiction to...
|
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| TN4440 |
Limonexic acid |
Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively prote...
|
|
| TN4322 |
Isopulegol |
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
|
|
| TN4298 |
Isohyenanchin |
Isohyenanchin is the potent antagonist of RDLac homo-oligomers, it is also a weak antagonist of ionotropic GABA receptors.
|
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| TN3868 |
Dihydroxyaflavinine |
Dihydroxyaflavinine is a fungal toxin, it inhibits non-competitively GABAA receptor channel expressed in Xenopus oocytes.Dihydroxyaflavinine shows oral toxicity ...
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| T16581 |
Progabide |
Progabide is an agonist of the gamma-aminobutyric acid receptor.
|
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| T11686 |
Isotanshinone I |
Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and...
|
|
| T3S2100 |
Securinine |
(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.
|
|
| TN1842 |
Kushenol I |
Kushenol I is a GABAA receptor modulator, it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).Kushenol I is shown to be activ...
|
|
| T11061 |
DMCM hydrochloride |
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA zaerxep3 receptor s...
|
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| T12492 |
Pivagabine |
Pivagabine is a derivative of hydrophobic 4-aminobutyric acid, with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine a...
|
|
| T12207 |
NEO 376 |
NEO 376 is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
|
|
| T12044 |
(-)-Bicuculline methochloride |
(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
|
|
| T12043 |
(-)-Bicuculline methobromide |
(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
|
|
| TN2268 |
Tetrahydromagnolol |
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
|
|
| TN1717 |
Guvacine |
Guvacine can enhance the inhibition of spinal neurones by GABA.
|
|
| T13536 |
Afoxolaner |
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
|
|
| TN1591 |
DL-Menthol |
DL-Menthol has short term toxicity in rats, it plays a role in the induction of surgical anesthesia in fishes, related at least in part to the activation of GABA...
|
|
| TN1432 |
Bacopasaponin C |
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
|
|
| TN1420 |
Bacopaside I |
Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS...
|
|
| TN1217 |
2'-O-Methylisoliquiritigenin |
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-re...
|
|
| TN1202 |
(1S)-(-)-Alpha-Pinene |
(1S)-(-)-Alpha-Pinene enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial ...
|
|
| T7699 |
AZD-7325 |
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
|
|
| T8162 |
Cannabidivarin |
Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood absence epilep...
|
|
| T14571 |
Bifenazate |
Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm[1] and it also is a positive allosteric modulator of GABA receptor[2]...
|
|
| T14938 |
CGP 36742 |
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is usef...
|
|
| T11684 |
Isoguvacine hydrochloride |
Isoguvacine hydrochloride is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α...
|
|
| T11307 |
Fluxametamide |
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- an...
|
|
| T19624 |
Fasoracetam |
Fasoracetam is a modulator of GABA receptor potentially for the treatment of attention deficit hyperactivity disorder.
|
|
| T15737 |
Lesogaberan |
Lesogaberan is an effective and selective GABAB receptor agonist (EC50: 8.6 nM for human recombinant GABAB receptors). For rat brain GABAB and GABAA receptors, t...
|
|
| T10618 |
Broflanilide |
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
|
|
| T10456 |
Bamaluzole |
Bamaluzole is an agonist of GABA receptor extracted from patent WO 2012064642 A1.
|
|
| T11350 |
GABAB receptor antagonist 1 |
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective a...
|
|
| T11349 |
GABAA receptor agent 1 |
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
|
|
| T11277 |
FG 7142 |
FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation an...
|
|
| T14983 |
Clomethiazole |
Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlorm...
|
|
| T13690 |
Etifoxine hydrochloride |
Etifoxine is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, etifoxine appears to produce its anxiolytic effects by binding to β2 and β3 subuni...
|
|
| T11137 |
(E)-GABAB receptor antagonist 1 |
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.(E)-GABAB receptor antagonist 1 is a trans-G...
|
|
| T13150 |
THIP |
THIP has a strong affinity for the δ subunit of GABAA receptors. THIP is a functionally selective GABAAR ligand, agonistic to α4β1δ, α4β3δ, and weakly ant...
|
|
| T12867 |
SCH 50911 hydrochloride |
SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).
|
|
| T15380 |
Gidazepam |
Gidazepam is an GABA receptor channels agonist.
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| T15212 |
Emamectin Benzoate |
Emamectin Benzoate, by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as ...
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| T10869L |
CP-409092 |
CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.
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| T1602 |
Valproic acid sodium salt |
Valproate Sodium is the sodium salt form of valproic acid with anti-epileptic activity. Valproate sodium is converted into its active form, valproate ion, in blo...
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