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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19642 | Nilofabicin | CG 0549,CG-0549,CG-400549,CG 400549,CG0549,CG400549 | Antibacterial |
Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute. | |||
T4105 | AFN-1252 | Debio 1452,API-1252 | Others , Antibacterial , Antibiotic |
AFN-1252 (Debio 1452)(Debio 1452) is an effective inhibitor of enoyl-acyl carrier protein reductase (FabI). It (≤0.12 μg/ml) inhibits all Clinicalal isolates of Staphylococcus aureus and Staphylococcus epidermidis. | |||
T70499 | Afabicin diolamine | ||
Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an enoyl-acyl carrier protein reductase (FabI) inhibitor, and is a first-in-class antibiotic with a novel mode of action to specifically tar... | |||
T37070 | Pyridomycin | ||
Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (A... | |||
T73032 | MtInhA-IN-1 | ||
MtInhA-IN-1 is a selective and orally active Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhibitor with an IC 50 of 0.23 μM. MtInhA-IN-1 potently against M. tuberculosis H37Rv ... |
Cat No. | Product Name | Synonyms | Targets |
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T38069 | Aquastatin A | ||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02703 | HEBP1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the ... |