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Search Results for " cytochrome p450 3a4 "

Targets

8

Compounds

1

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1743 Aprepitant MK-869,MK-0869,L-754030,Aprepitant` HIV Protease , Antibacterial , Antibiotic , Neurokinin receptor
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and C...
T2393 Efavirenz EFV,DMP 266,Sustiva,Stocrin,L-743726 HIV Protease , Reverse Transcriptase , Autophagy
Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P...
T1434 Clarithromycin A-56268 P450 , ribosome , MRP , Antibacterial , Antibiotic , Autophagy
Clarithromycin (A-56268) is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classif...
T63954 CYP3A4-IN-1
CYP3A4-IN-1 is a potent inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.085 μM).
T35714 N-Desethyl Vardenafil
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.
T64032 CYP3A4-IN-3
CYP3A4-IN-3 is a specific, highly affinity cytochrome P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) inhibitor (IC50: 0.075 μM). CYP3A4-IN-3 is an analogue of ritonavir with a simpler structure and twice as much inhibi...
T64037 CYP3A4-IN-2
CYP3A4-IN-2 is a specific inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.055 μM). CYP3A4-IN-2 is a ritonavir analogue with a more hydrophobic R2 side group and stronger inhibition than ritonavir. CYP3A4-IN-2 is capab...
T37788 Resorufin benzyl ether
Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4. It is typically used near its apparent Km value of 30 μM to screen the inhibition/activation potential of test compoun...
Cat No. Product Name Synonyms Targets
T82556 Dihydrocubebin (-)-Dihydrocubebin
Dihydrocubebin, isolated from Piper cubeba, serves as a potent and selective inhibitor of cytochrome P450 3A4 (CYP3A4) [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05321 CYP3A4 Protein, Human, Recombinant (His) Human E. coli
CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-dr...
TargetMol