T2154 |
MG132HOT |
MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
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T27695 |
JTE-607 HCl |
JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.
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T0448 |
Dexibuprofen |
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
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T4403 |
AX-024 HCl |
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interf...
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T6040 |
Aloxistatin |
Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibito...
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T2470 |
Calpain Inhibitor III |
Calpain Inhibitor III is a Cysteine protease.
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T6573 |
Loxistatin Acid |
Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
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T6037 |
E64 |
E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
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T6035 |
Odanacatib |
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
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T1080 |
2-Aminoethanethiol |
Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
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T1850 |
Balicatib |
Balicatib is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
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T7451 |
2-cyano-Pyrimidine |
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM)
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T0789 |
PMSF |
Phenylmethanesulfonyl fluoride (PMSF) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
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T6015 |
Cathepsin Inhibitor 1 |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
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T6738 |
Z-FA-FMK |
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
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T2493 |
PD 151746 |
PD 151746 is a selective, cell-permeable calpain inhibitor (Ki: 0.26/5.33 μM, μ-Calpain/m-calpain).
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T3420 |
CA-074 methyl ester |
CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
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T3088 |
N-Ethylmaleimide |
N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
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T6432 |
Calpeptin |
Calpeptin is a potent, cell-permeable calpain inhibitor.
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T5211 |
NSC185058 |
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.
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TQ0116 |
LY 3000328 |
LY 3000328 is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
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T21616 |
L 006235 |
L 006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
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T16474 |
Petesicatib |
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
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T20626 |
Esomeprazole |
Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibit...
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TJS2216 |
Aurantiamide acetate |
Aurantiamide acetate was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally act...
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T17026 |
Tecovirimat |
Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective a...
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T17026 |
Tecovirimat |
Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective a...
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T6583 |
MG101 |
MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
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T11896 |
LV-320 |
LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo. LV-320 is a potent and uncompetitive ATG...
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T11846 |
LHVS |
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine prote...
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T16394 |
ONO-5334 |
ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 ...
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T12051 |
MIV-247 |
MIV-247 is a selective inhibitor of cathepsin S (human, mouse and cynomolgus monkey cathepsin S with Kis of 2.1, 4.2 and 7.5 nM , respectively).
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T16106 |
ML224 |
ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM).
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T13439 |
(RS)-Butyryltimolol |
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol is a β-adrenergic blocker.
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T15641 |
K777 |
K777 is an orally active and irreversible cysteine protease inhibitor. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 is al...
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T11554 |
Cathepsin Inhibitor 2 |
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
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T13705 |
GLPG2451 |
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11....
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T12909 |
SID 26681509 |
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
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T12819 |
S130 |
S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 µM).It suppresses autophagy flux.
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T10924 |
Cysteine protease inhibitor-2 |
Cysteine protease inhibitor 2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor 2 inhibited DCT116...
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T6564 |
Leupeptin Hemisulfate |
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
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