Cysteine Protease

Cat No.	product name
T2154	MG132HOT	MG-132 is a potent cell-permeable 20S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
T21616	L 006235	L 006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
T1850	Balicatib	Balicatib is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
T2470	Calpain Inhibitor III	Calpain Inhibitor III is a Cysteine protease.
T6573	Loxistatin Acid	Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
T6037	E64	E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
T6035	Odanacatib	Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
T1080	2-Aminoethanethiol	Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T0448	Dexibuprofen	Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
T0789	PMSF	Phenylmethanesulfonyl fluoride (PMSF) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
T4403	AX-024 HCl	AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interf...
T6015	Cathepsin Inhibitor 1	Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
T6738	Z-FA-FMK	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
T2493	PD 151746	PD 151746 is a selective, cell-permeable calpain inhibitor (Ki: 0.26/5.33 μM, μ-Calpain/m-calpain).
T3420	CA-074 methyl ester	CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
T3088	N-Ethylmaleimide	N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
T6432	Calpeptin	Calpeptin is a potent, cell-permeable calpain inhibitor.
T6040	Aloxistatin	Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibito...
T5211	NSC185058	NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.
T17026	Tecovirimat	Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective a...
T13439	(RS)-Butyryltimolol	(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol is a β-adrenergic blocker.
T17026	Tecovirimat	Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective a...
T6583	MG101	MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
T11896	LV-320	LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo. LV-320 is a potent and uncompetitive ATG...
T11846	LHVS	LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine prote...
T16474	Petesicatib	Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
T16394	ONO-5334	ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 ...
T16106	ML224	ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM).
T15641	K777	K777 is an orally active and irreversible cysteine protease inhibitor. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 is al...
T7451	2-cyano-Pyrimidine	2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM)
T11554	Cathepsin Inhibitor 2	Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
T13705	GLPG2451	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11....
T12909	SID 26681509	SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
T12819	S130	S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 µM).It suppresses autophagy flux.
T10924	Cysteine protease inhibitor-2	Cysteine protease inhibitor 2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor 2 inhibited DCT116...
T12051	MIV-247	MIV-247 is a selective inhibitor of cathepsin S (human, mouse and cynomolgus monkey cathepsin S with Kis of 2.1, 4.2 and 7.5 nM , respectively).
TQ0116	LY 3000328	LY 3000328 is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
T6564	Leupeptin Hemisulfate	Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.