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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2499 | Torcetrapib | CP-529414 | CETP |
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces... | |||
T6262 | Evacetrapib | LY2484595 | CETP |
Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. | |||
T1928 | Anacetrapib | MK-0859 | CETP |
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th... | |||
T6048 | Dalcetrapib | JTT-705,RO4607381 | CETP |
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol. | |||
T28225 | Obicetrapib | TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 | CETP |
Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein. | |||
T68416 | DRL-17822 | ||
DRL-17822 is a Cholesteryl Ester Transfer Protein (CETP) inhibitor. | |||
T14976 | CKD-519 | Others | |
CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM). | |||
T68265 | PF-04445597 | ||
PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP). | |||
T39137 | CETP-IN-4 | ||
CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor. | |||
T69672 | MK-825 | ||
MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor. | |||
T36139 | BMS-795311 | ||
Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable. Qiao... | |||
T13079 | TAP311 | CETP | |
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM). | |||
T68505 | Obicetrapib sodium | ||
Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial ... | |||
T68504 | Obicetrapib calcium | ||
Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial... | |||
T68503 | Obicetrapib potassium | ||
Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible benefici... | |||
T38908 | MK-8262 | ||
MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN5057 | Stachybotramide | LDL | |
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) a... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02264 | TNFSF11 Protein, Human, Recombinant (His) | Human | HEK293 |
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the tria... |
Cat No. | Product Name | ||
---|---|---|---|
L2510 | Lipid Metabolism Compound Library | 496 compounds | |
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). |