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Cat No. | Product Name | Synonyms | Targets |
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T2126 | MK-5046 | Bombesin Receptor | |
MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM). | |||
T4540 | ML-18 | Bombesin Receptor | |
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM. | |||
TP1701 | RC-3095 TFA | RC-3095 (TFA) | Bombesin Receptor |
RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity. | |||
TP1913L1 | BA 1 acetate(183241-31-8 free base) | Bombesin Receptor | |
BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 ... | |||
TP1931L1 | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base) | cholecystokinin |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ... | |||
T20413 | Spantide I | Spantide | |
Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist. | |||
T71596 | Bag-2 | ||
Bag-2 is a Novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist. | |||
TP2239 | [D-Phe12]-Bombesin | Others | |
Bombesin receptor antagonist | |||
T33439 | MK-7725 | MK7725 | |
Mk-7725 is an effective selective bombesin receptor subtype 3 agonist for the treatment of obesity. | |||
T25522 | Ici 216140 | m216140,Ici216140,m 216140,Ici-216140,m-216140 | |
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated... | |||
TP1916 | [D-Phe12,Leu14]-Bombesin | ||
Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo. | |||
T71595 | Bag-1 | ||
Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist. | |||
T75945 | BA 1 TFA | ||
BA 1 TFA acts as a potent agonist for the bombesin (BB) family of receptors, exhibiting high affinity binding to Bombesin receptor subtype-3 (BRS3), gastrin-releasing peptide receptor (GRPR), and neuromedin B receptor (N... | |||
TP1913 | BA 1 | ||
Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell p... | |||
T35669 | Neuromedin C (trifluoroacetate salt) | ||
Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide... | |||
TP2153 | RC-3095 acetate | Others | |
RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice. | |||
TP1931 | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P | ||
Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradyki... | |||
T75707 | BIM-26226 | ||
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is ut... | |||
T83490 | [Lys3]-Bombesin | ||
[Lys3]-Bombesin is a biologically active peptide used in PET (Positron Emission Tomography) imaging to identify GRPR (gastrin-releasing peptide receptor) positive prostate cancer. The compound, when conjugated with a cor... | |||
TP2026 | GRP (porcine) | ||
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA re... |
Cat No. | Product Name | Synonyms | Targets |
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TN1849 | Kuwanon H | GPR , Bombesin Receptor | |
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP. | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
T20604L | Litorin acetate(55749-97-8 Free base) | Bombesin Receptor | |
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n... |