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Search Results for " bombesin-receptor "

Targets

20

Compounds

3

Natural Products

Cat No. Product Name Synonyms Targets
T2126 MK-5046 Bombesin Receptor
MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).
T4540 ML-18 Bombesin Receptor
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.
TP1701 RC-3095 TFA RC-3095 (TFA) Bombesin Receptor
RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.
TP1913L1 BA 1 acetate(183241-31-8 free base) Bombesin Receptor
BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 ...
TP1931L1 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base) cholecystokinin
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ...
T20413 Spantide I Spantide
Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.
T71596 Bag-2
Bag-2 is a Novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.
TP2239 [D-Phe12]-Bombesin Others
Bombesin receptor antagonist
T33439 MK-7725 MK7725
Mk-7725 is an effective selective bombesin receptor subtype 3 agonist for the treatment of obesity.
T25522 Ici 216140 m216140,Ici216140,m 216140,Ici-216140,m-216140
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated...
TP1916 [D-Phe12,Leu14]-Bombesin
Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T71595 Bag-1
Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.
T75945 BA 1 TFA
BA 1 TFA acts as a potent agonist for the bombesin (BB) family of receptors, exhibiting high affinity binding to Bombesin receptor subtype-3 (BRS3), gastrin-releasing peptide receptor (GRPR), and neuromedin B receptor (N...
TP1913 BA 1
Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell p...
T35669 Neuromedin C (trifluoroacetate salt)
Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide...
TP2153 RC-3095 acetate Others
RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice.
TP1931 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradyki...
T75707 BIM-26226
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is ut...
T83490 [Lys3]-Bombesin
[Lys3]-Bombesin is a biologically active peptide used in PET (Positron Emission Tomography) imaging to identify GRPR (gastrin-releasing peptide receptor) positive prostate cancer. The compound, when conjugated with a cor...
TP2026 GRP (porcine)
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA re...
Cat No. Product Name Synonyms Targets
TN1849 Kuwanon H GPR , Bombesin Receptor
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP.
T3S1612 Kuwanon G Moracenin B,Kuwanone G Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
T20604L Litorin acetate(55749-97-8 Free base) Bombesin Receptor
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n...
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