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Cat No. | Product Name | Synonyms | Targets |
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T36314 | Wortmannin-Rapamycin Conjugate | ||
Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer. Wortmannin is a potent inhibitor of PI3K enzymes, while rapamycin blocks mTOR Complex 1 TORC1. Wortmannin... | |||
T1661 | Crizotinib | PF-02341066 | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor. | |||
T64164 | Topoisomerase II inhibitor 11 | ||
Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM). Topoisomerase II inhibitor 11 inhibits cell proliferation and has apoptotic activity by blocking the cell cycle in th... |
Cat No. | Product Name | Synonyms | Targets |
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T83435 | 19-Hydroxy-10-deacetylbaccatin III | ||
19-Hydroxy-10-deacetylbaccatin III (compound 13), a taxane potentially active against tumors, exhibits low cytotoxicity towards A498 and NCI-H226 cell lines. At a concentration of 30 μg/mL, it inhibits A498 and NCI-H226 ... | |||
T83471 | 10-Deacetyl-13-oxobaccatin III | ||
10-Deacetyl-13-oxobaccatin III, a taxane isolated from Taxus sumatrana, exhibits cytotoxicity at a concentration of 30 μg/mL, inhibiting A498, NCI-H226, A549, and PC-3 cancer cell lines with respective rates of 29.7%, 49... | |||
T36439 | Gramicidin A | Antibacterial , HIF , Parasite | |
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t... |