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Results for "
zio-201
" in TargetMol Product Catalog- Inhibitors & Agonists3
Palifosfamide
ZIO-201, Isophosphoramide mustard, Isophosphamide mustard
T435031645-39-3
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines except OS222 (IC50=31.5 μM).
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Palifosfamide tromethamine
ZIO-201 tromethamine, Isophosphoramide mustard tromethamine, IPM tromethamine
T715001070409-31-2
Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide.
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