wilfordii

1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.

Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 expression.

Triptonoterpene is a natural product found in Tripterygium wilfordii and Tripterygium doianum. Triptonoterpene is an abietane diterpenoid.

Triptotriterpenic acid A, a natural product isolated from *Tripterygium wilfordii*,

Wilforlide A (3-Epiabruslactone A) is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity.

Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.

Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.

Peritassine A, an alkaloid derived from Tripterygium wilfordii Hook. f., exhibits anti-HIV properties.

Wilforine, a sesquiterpene pyridine alkaloid, is an important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis. Wilforine exhibits an anti-inflammatory effect, which might be mediated by the down-regulation of inflammatory factors TNF-α, IL-6, and NO. Additionally, it has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Triptotriterpenic acid C, an ursolic-type compound, can be isolated from the total glycosides extracted from the root of Tripterygium wilfordii Hook.f [1].

Triptonoterpenol (Compound 6) is a secondary metabolite derived from Tripterygium wilfordii [1].

Triptonoterpene Me ether (compound 5), a rosinane-type diterpenoid, is derived from the traditional Chinese medicinal plant, Tripterygium wilfordii Hook. f [1].

Triptonoditerpenic acid is an aromatic pimarane diterpenoid that can be isolated from Tripterygium wilfordii. It exhibits cytotoxicity against HepG2, Hep3B, and Bcap37 cell lines, with IC50 values of 42.53 μM, 29.74 μM, and 37.63 μM, respectively.

Triptophenolide (Standard) is a reference standard for research and analysis in studies involving Triptophenolide. Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.

Wilforine (Standard) is a reference standard for research and analysis in studies involving Wilforine. Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Demethylzeylasteral (Standard) is a reference standard for research and analysis in studies involving Demethylzeylasteral. Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.

(5R)-5-Hydroxytriptolide, a compound extracted from Tripterygium wilfordii, exhibits lower cytotoxicity and higher immunosuppressive activity. It is useful for research in rheumatoid arthritis.

(-)-Celallocinnine (MOL003209) is an orally active component derived from Tripterygium wilfordii. It is utilized in research related to diabetic nephropathy.

Ejaponine B is a natural compound found in Tripterygium wilfordii and Begonia fimbristipulata.

Celangulin II is a natural product found in Tripterygium wilfordii and Daphniphyllum macropodum.

Celangulatin F is a natural compound found in the plants Tripterygium wilfordii and Begonia grandis.

Celangulin III is a naturally occurring compound found in Tripterygium wilfordii and Begonia fimbristipula.

Regelidine is a diterpenoid constituent of Tripterygium wilfordii Hook. F. (TwHF), a traditional Chinese plant extensively used in the clinical management of rheumatoid arthritis. Regelidine, belonging to a diterpenoid chemical framework composed of four isoprene units, has been found to exert antiviral and antimicrobial activities, supporting its therapeutic potential in infectious and immune-related disease treatment strategies.

Triptinin B (compound 2) is a LTD4 antagonist that can be isolated from Tripterygium wilfordii. Triptinin B (compound 2) is utilized in biochemical research focused on leukotriene signaling pathways, inflammatory mediator receptor modulation, and lipid-derived inflammatory cascade regulation.