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Results for "
vu-29
" in TargetMol Product Catalog- Inhibitors & Agonists2
VU-29
VU 29
T23515890764-36-0
VU-29 is a positive allosteric mGlu5 receptor modulator with an EC50 of 9 nM and a Ki of 244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes [EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM].
- $29
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QTY
Valiglurax
VU-2957, VU2957, VU-0652957, VU0652957, VU 2957, VU 0652957
T350281976050-09-5
Valiglurax (VU2957), also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in vitro and in vivo pharmacological and DMPK properties across species. VU2957 was evaluated as a preclinical development candidate for the treatment of Parkinson's disease.
- $31
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