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By Target- MDM-2/p53
- p53(1)
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Results for "
usp7in4
" in TargetMol Product Catalog- Inhibitors & Agonists2
USP7-IN-4
USP7-IN-2, USP7 inhibitor ALM4, AD-04
T698202196243-57-7
USP7-IN-4(USP7 inhibitor ALM4) is a non-competitive, potent and selective inhibitor of USP7 (ubiquitin-specific protease 7) with an IC50 = 6 nM, up-regulates p53 and p21, down-regulates MDM2, increases the level of ubiquitination of MDM2, and exhibits anti-proliferative activity in a variety of cancer cell lines, with an EC50 = 2.0 nM in RS4;11 (acute lymphoblastic leukemia cell line) .
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