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(3)
By Target- DUB
- MDM-2/p53(1)
- p53(1)
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By Target By ResearchField- Cancer(3)
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Results for "
usp7-in-6
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- USP7-IN-4USP7-IN-2, USP7 inhibitor ALM4, AD-04T698202196243-57-7USP7-IN-4(USP7 inhibitor ALM4) is a non-competitive, potent and selective inhibitor of USP7 (ubiquitin-specific protease 7) with an IC50 = 6 nM, up-regulates p53 and p21, down-regulates MDM2, increases the level of ubiquitination of MDM2, and exhibits anti-proliferative activity in a variety of cancer cell lines, with an EC50 = 2.0 nM in RS4;11 (acute lymphoblastic leukemia cell line) .
- $333
SizeQTY - USP7-IN-8GNE-6776T92172009273-60-1Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 (GNE-6776) has anticancer effects.
- $40
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