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trpm4-in-2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
TRPM4-IN-2
NBA
T61275667411-04-3
TRPM4-IN-2 (NBA), also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an IC 50 value of 0.16 μM. This compound serves as a valuable tool in the investigation of prostate cancer and colorectal cancer [1] [2].
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6-8 weeks
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NMDAR/TRPM4-IN-2
T726622243506-33-2
NMDAR TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR TRPM4 interaction.NMDAR TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.
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6-8 weeks
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TRPM4-IN-1
CBA, 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
T9245351424-20-9
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
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