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tropical diseases

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    1
    TargetMol | Compound_Libraries
  • Natural Products
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    TargetMol | Natural_Products
AWZ1066S
T104232239272-16-1
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).
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Diarctigenin
T209108
Diarctigenin is a selective inhibitor of Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS), and it is applicable in the study of tropical diseases.
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Antileishmanial agent-26
T209377
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with activity against *Leishmania donovani*, exhibiting an IC50 value of 5.67 μM and a CC50 value of 3.79 μM in THP-1 cells. This compound is applicable for research in tropical diseases.
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Pelorol
(-)-Pelorol
TN11522287974-44-1
Pelorol ((-)-Pelorol) is a sesquiterpene compound identified in the tropical marine sponge Dactylospongia elegans. It exhibits mild trypanocidal activity with an IC50 value of 17.4 μg/mL and demonstrates antimalarial properties against Plasmodium falciparum clones K1 and NF54, with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol shows potential for research in parasitic diseases, including trypanosomiasis and malaria.
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10-14 weeks
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