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By Target- Thyroid hormone receptor(THR)
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Results for "
tr antagonist 1
" in TargetMol Product Catalog- Inhibitors & Agonists2
TR antagonist 1
T13435500794-88-7
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities.
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CELT-133
T83956
CELT-133 is a selective fluorescent antagonist for the hα1A adrenergic receptor, demonstrating complete selectivity towards α1A over α2A receptors, with a Ki of 5 nM and 15% displacement at 1 μM in radioligand binding assays, respectively. It displays equivalent affinity across all α1 adrenergic receptor subtypes. Notably, CELT-133 features excitation and emission maxima (λ) at 560 and 571 nm, respectively, making it suitable for use as an acceptor dye in time-resolved Förster resonance energy transfer (TR-FRET) assays when paired with the CoraFluor 1 TR-FRET donor.
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