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By Target- Cholinesterase (ChE)
- mTOR(1)
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Results for "
timosaponin aiii
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Timosaponin AIII
Timosaponin A3, Filiferin B, AneMarsaponin A3
T339541059-79-4
Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
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