this compound sodium

DIDS sodium salt (MDL101114ZA) is a small molecule inhibitor that acts as a dual-target inhibitor of both ABCA1 and VDAC1, suppressing RAD51-mediated homologous recombination. This compound inhibits anion exchange and Caspase-3/-9 activation, and is used in cancer research.

CGamF is a fluorescent probe designed for bile acid transport, consisting of a bile acid (Product No. 20250) linked to fluorescein via a glycine connecting group. In aqueous solution at pH 7.4, the excitation/emission wavelengths of this probe are 492/515 nm, respectively. The fluorescence intensity of CGamF increases with rising pH when excited at 495 nm, while the intensity is unaffected by pH changes when excited at 440 nm. Sodium-dependent uptake of CGamF by hepatocytes increases with the concentration of the compound, with reduced absorption at lower sodium levels. CGamF has been utilized in vitro to study drug interactions and toxicity mediated by hepatic transporters.

BP Fluor 405 acid is a water-soluble blue fluorescent dye frequently utilized in multicolor applications, such as flow cytometry and super-resolution microscopy with STORM. It is optimally excited by either the 407 nm spectral line of a krypton laser or a 408 nm violet laser diode. This compound is pH insensitive across the range of pH 4 to pH 10. The carboxylic acid form of BP Fluor 405 serves as an ideal reagent for synthesizing custom active esters not typically available commercially, such as sulfo-NHS, TFP (2,3,5,6-tetrafluorophenol), and STP (4-sulfo-2,3,5,6-tetrafluorophenol, sodium salt). Another prevalent use of non-activated carboxylic acids is in peptide modification during solid-phase synthesis, often requiring in situ activation with peptide coupling reagents like HATU. Additionally, BP Fluor 405 acid is commonly used for control experiments and calibration.

4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium serves as a fluorescent substrate for iduronate-2-sulfatase (I2S). This compound can be hydrolyzed by the lysosomal enzyme α-L-iduronidase (IDUA), liberating the fluorophore 4-Methylumbelliferone. It is utilized in the detection of Hurler syndrome.

Rhodamine-Alginate is a Rhodamine B-labeled sodium alginate. This compound merges the polysaccharide characteristics of sodium alginate with the fluorescent properties of Rhodamine B, playing a crucial role in fluorescence labeling, cell imaging, and drug delivery research (Ex/Em = 546/610 nm).

CY5-Alginate is a sodium alginate labeled with CY5. This compound merges the polysaccharide properties of sodium alginate with the fluorescent characteristics of CY5, playing a crucial role in fields such as fluorescence labeling, cell imaging, and drug delivery research (Ex/Em = 633/670 nm).

CY7.5-Alginate is a CY7.5-labeled sodium alginate. This compound merges the polysaccharide characteristics of sodium alginate with the fluorescent properties of CY7.5, playing a crucial role in fields such as fluorescence labeling, cell imaging, and drug delivery research (Ex/Em = 770/820 nm).

CY5.5-Alginate is a CY5.5-labeled sodium alginate. This compound merges the polysaccharide properties of sodium alginate with the fluorescent characteristics of CY5.5, making it significant in areas such as fluorescence labeling, cell imaging, and drug delivery research (Ex/Em = 680/710 nm).

FITC-Alginate is an FITC-labeled sodium alginate. This compound combines the polysaccharide characteristics of sodium alginate with the fluorescent properties of FITC, playing a significant role in areas such as fluorescence labeling, cell imaging, and drug delivery research (Ex/Em = 488/525 nm).

ING-2 AM is a membrane-permeable fluorescent indicator specifically designed for sodium ions (Na+), exhibiting a binding affinity with a dissociation constant (Kd) of 20 mM. With excitation and emission maxima (λ) at 525 nm and 545 nm respectively, this compound achieves a 20-fold selectivity over potassium ions (K+). It is utilized both in vitro and in situ to monitor real-time sodium influx.

IPG-4 AM, a membrane-permeable fluorescent indicator, specifically binds to potassium ions (K+) with a dissociation constant (Kd) of 7 mM. This compound exhibits excitation and emission maxima (λ) at 525 nm and 545 nm, respectively, and displays a 100:1 selectivity for K+ over sodium ions (Na+). It is utilized for real-time detection of intracellular K+ levels, as well as monitoring extracellular K+ changes in vivo.

Bathophenanthroline disulfonic acid sodium, a versatile dye, plays a crucial role across various domains, from basic scientific research to clinical diagnostics. This compound aids in observing and analyzing cell structures, tracking biomolecules, evaluating cellular functions, differentiating cell types, detecting biomolecules, examining tissue pathology, and monitoring microorganisms. Its usage extends beyond the confines of biological experiments into traditional arenas such as textile dyeing, as well as emerging areas like functional textile processing, food pigments, and dye-sensitized solar cells.

BODIPY FL Ethylamine, a fluorescent dye, forms a reversible Schiff base when it reacts with aldehydes or ketones. This compound can be converted into a stable amine derivative through reduction with either sodium borohydride or sodium cyanoborohydride [1].

Rhodizonic Acid Disodium (Sodium Rhodizonate Dibasic) serves as an indicator for the volumetric analysis of barium and sulfates. This compound is categorized as a biological material or organic compound, extensively utilized in life science research.