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talmapimod

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Talmapimod
SCIO-469
T12871309913-83-5In house
Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
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Talmapimod hydrochloride
SCIO-469 hydrochloride
T12871L309915-12-6
Talmapimod hydrochloride is a selective and ATP-competitive p38α inhibitor (IC50: 9 nM). It also shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.
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3-6 months
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