tadalafil

Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby causing prolonged muscle relaxation, vasodilation, and enhanced penile erection.

ent-Tadalafil (ent-IC-351), compound (6S,12aS), is an inactive cis-enantiomer of compound (6R,12aS).

N-Ethyl tadalafil (NEthyl tadalafil) is a CGMP-specific 3',5'-cyclic phosphodiesterase (PDE) inhibitor used in the study of cardiovascular diseases such as angina pectoris, hypertension, and pulmonary hypertension.

cis-Tadalafil (cis-IC-351) is a potent PDE5 inhibitor with an IC50 value of 0.09 μM that can be used to study arterial hypertension.

Tadalafil hydroxypiperidone is an impurity of Tadalafil -- a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction.

Desmethylene Tadalafil is a phosphodiesterase 5 inhibitor.

Tadalafil-D3 is a deuterated compound of Tadalafil. Tadalafil (T1398) has a CAS number of 171596-29-5. Tadalafil (T1398) is a carboline-based compound with vasodilatory activity. Tadalafil (T1398) selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Tadalafil impurity 16 is a constituent impurity of Tadalafil.

Tadalafil impurity 3 (Tadalafil impurity I) is an impurity of Tadalafil.

Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.

Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.

cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure. cis-ent-Tadalafil is a potent and selective PDE5 inhibitor that reduces blood pressure.

Tadalafil-13C-D3 is a carboline-based compound with vasodilatory activity. Tadalafil (T1398) selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Amino Tadalafil (Standard) is the standard substance of Amino Tadalafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.

Nortadalafil (Standard) is the standard substance of Nortadalafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.

Tadalafil (Standard) is the standard substance of Tadalafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

N-phenylpropenyl Tadalafil (Standard) is a reference standard of N-phenylpropenyl Tadalafil intended for quantitative analysis, quality control, and related biochemical research applications.

N-Butyl Tadalafil (Standard) is a reference standard of N-Butyl Tadalafil intended for quantitative analysis, quality control, and related biochemical research applications.

Tadalafil-13C-D3 (Standard) is a reference standard of Tadalafil-13C-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Tadalafil-13C-d3 the 13C and deuterated compound of Tadalafil. Tadalafil has a CAS number of 171596-29-5. Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Tadalafil impurity 1 (Tadalafil impurity D) is an impurity of Tadalafil.

Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.

Acetaminotadalafil is a new analogue of Tadalafil used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor.

Acetaminotadalafil (Standard) is the standard substance of Acetaminotadalafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Acetaminotadalafil is a new analogue of Tadalafil used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor.

Chloropretadalafil (Standard) is a reference standard of Chloropretadalafil intended for quantitative analysis, quality control, and related biochemical research applications.