t2404

Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19 nM at pH 6.5.

L-erythro-Sphingosine is an L-isomer of sphingosine.

ERDRP-0519 is an orally bioavailable small-molecule inhibitor of the Measles virus (MeV) polymerase. It effectively prevents measles disease in squirrel monkeys (Saimiri sciureus) and exhibits potent inhibition of morbilliviruses in the nanomolar range.

WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.

WNK-IN-11-D3 is an effective, selective, and orally active WNK1 kinase inhibitor.

Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.

WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.