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t-5224

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
  • PROTAC Products
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    TargetMol | PROTAC
T-5224
T5416530141-72-1
T-5224 is a transcription factor c-Fos AP-1 inhibitor that specifically inhibits the DNA-binding activity of c-Fos c-Jun without affecting other transcription factors.
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FOSL1 degrader 1
T89624
FOSL1 degrader 1 (4) is a potent T-5224-PROTAC that effectively degrades FOSL1 (AP-1), thereby suppressing the expression of cancer stemness genes in HNSCC. By degrading FOSL1, it inhibits tumor growth and effectively eliminates cancer stem cells in HNSCC tumors. This compound demonstrates an efficacy 30 to 100 times greater than that of T-5224.
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