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spr-00305
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Ibrexafungerp citrate
SCY-078 citrate, SCY078 citrate, MK3118 citrate, MK 3118 citrate
T700291965291-08-0
Ibrexafungerp citrate is a triterpenoid antifungal agent that inhibits the synthesis of 1,3-β-D-glucan in fungal cell walls, and although its functional outcome is similar to echinocandins, it binds to a distinct site on the glucan synthase enzyme, resulting in limited cross-resistance. Ibrexafungerp citrate exhibit concentration-dependent fungicidal activity against Candida species and retaining strong in vitro efficacy against the majority of fluconazole-resistant strains, supporting its use in antifungal resistance and drug development research.
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