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  • Chloride channel
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spi 0211

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Lubiprostone
SPI-0211, RU-0211
T6307136790-76-6
Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
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Lubiprostone hemiketal
SPI-0211 hemiketal, RU-0211 hemiketa
T88362333963-40-9
Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.
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10-14 weeks
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